Showing 1-26 of 26 results for "88-05-1"
R Chen et al.
Journal of clinical pharmacy and therapeutics, 40(1), 110-115 (2014-09-25)
Research on genetic factors associated with antitubercular drug-induced liver injuries (ATLI) has been reported. However, most of the research has focused on genetic polymorphisms of genes encoding metabolic enzymes, including NAT2, GST and CYP450. It is probable that the immune...
Magdolna Kovács et al.
Peptides, 31(10), 1839-1846 (2010-07-17)
GHRH receptor antagonists inhibit growth and metastasis of a large number of experimental tumors expressing the pituitary GHRH receptor (pGHRH-R) and its major splice variant SV1. In this study, using Western blot, we demonstrated that DBTRG-05 and U-87MG human glioblastoma...
Micong Jin et al.
Se pu = Chinese journal of chromatography, 25(2), 214-216 (2007-06-22)
A simple, accurate and sensitive method has been developed for the simultaneous determination of warfarin, coumatetralyl, bromadiolone, flocoumafen and brodifacoum in whole blood by high performance liquid chromatography (HPLC) with fluorescence detection. The five 4-hydroxycoumarin rodenticides in whole blood were...
Yuan-Kai Cheng et al.
Archives of otolaryngology--head & neck surgery, 132(3), 285-290 (2006-03-22)
To assess the association of the interleukin (IL)-1beta and the IL-1 receptor antagonist (IL-1Ra) gene polymorphisms with chronic rhinosinusitis (CRS). Genotyping of the 2 IL-1beta gene (IL1B) polymorphisms (promoter and exon) and the IL-1Ra gene (IL1RN) polymorphism (intron 2) was...
Sönke Detlefsen et al.
Medicine, 97(31), e11641-e11641 (2018-08-05)
The diagnosis of autoimmune pancreatitis (AIP) and its differential diagnosis from pancreatic cancer (PC) can be challenging. In this retrospective study, we aimed to evaluate the value of anti-plasminogen binding peptide (a-PBP), immunoglobulin G4 (IgG4), and anti-carbonic anhydrase-II (a-CA-II), together...
Leah Winer et al.
JAMA neurology, 70(2), 201-207 (2012-11-14)
Therapies designed to decrease the level of SOD1 are currently in a clinical trial for patients with superoxide dismutase (SOD1)-linked familial amyotrophic lateral sclerosis (ALS). To determine whether the SOD1 protein in cerebral spinal fluid (CSF) may be a pharmacodynamic...
Stefan Dudli et al.
The spine journal : official journal of the North American Spine Society, 18(5), 831-844 (2017-12-19)
Modic changes (MCs) are magnetic resonance imaging (MRI) evidence of inflammatory and fibrotic vertebral bone marrow lesions that associate with adjacent disc degeneration and end plate damage. Although MC etiology is uncertain, historical data suggest a linkage to an autoimmune...
Lynne Lennard et al.
British journal of haematology, 169(2), 228-240 (2014-12-03)
The impact of thiopurine methyltransferase (TPMT) genotype on thiopurine dose intensity, myelosuppression and treatment outcome was investigated in the United Kingdom childhood acute lymphoblastic leukaemia (ALL) trial ALL97. TPMT heterozygotes had significantly more frequent cytopenias and therefore required dose adjustments...
Marije N van Doorn-van Atten et al.
The British journal of nutrition, 119(10), 1185-1194 (2018-05-16)
This study aimed to evaluate the effects of an intervention including nutritional telemonitoring, nutrition education, and follow-up by a nurse on nutritional status, diet quality, appetite, physical functioning and quality of life of Dutch community-dwelling elderly. We used a parallel...
J-E Eom et al.
Vox sanguinis, 107(2), 181-187 (2014-02-13)
Transplantation of cryopreserved umbilical cord blood (UCB) can be used to treat a multitude of haematologic and immunological diseases. In this study, we examined the quality of UCB cryopreserved for 2 (group I), 4 (group II) and 6 (group III)...
Limin Fan et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 35(2), 88-95 (2019-02-12)
To observe the epithelial remodeling over a 9-mm diameter cornea induced by topography-guided femtosecond laser-assisted in situ keratomileusis (FS-LASIK) for myopia correction using spectral-domain optical coherence tomography (SD-OCT). Forty-three eyes of 22 patients who underwent topography-guided FS-LASIK for myopic correction...
Niikee C Schoendorfer et al.
European journal of clinical investigation, 42(7), 768-776 (2012-02-04)
Methylation cycle and folate-mediated one-carbon metabolism maintenance is important for many physiological processes including neurotransmitter regulation, nerve myelination and DNA synthesis. These processes play an indispensible role in growth and development, as well as in cognitive function and neuromuscular stability...
Angelo Di Leo et al.
The Lancet. Oncology, 12(12), 1134-1142 (2011-09-16)
Prediction of response to anthracycline-based therapy for breast cancer is challenging. We aimed to assess the value of HER2 and TOP2A as predictive markers of response to anthracycline-based adjuvant therapy in patients with early breast cancer. We did a meta-analysis...
Hector Chinoy et al.
Rheumatology (Oxford, England), 48(10), 1213-1217 (2009-08-20)
The HLA 8.1 ancestral haplotype (HLA-B*08/DRB1*03/DQA1*05/DQB1*02) is associated with adult/juvenile idiopathic inflammatory myopathy (IIM), but confers a greater strength of association in patients possessing anti-Jo-1 or anti-PM-Scl antibodies. The HLA-DPB1 gene is centromeric to other HLA class II loci and...
J Glenn et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 6(3), 462-468 (1988-03-01)
By radioimmunoassay we determined circulating levels of a tumor-associated antigen, CA 19-9, in 47 patients with pancreatic adenocarcinoma, to learn if serial testing was useful in predicting prognosis or in detecting disease progression. Before treatment, 42 (89%) had an abnormal...
Z M Estrada-Reyes et al.
Parasite immunology, 37(9), 446-452 (2015-06-23)
Haemonchus contortus is a parasitic nematode of Pelibuey sheep, a meat breed used in tropical regions. Due to anthelmintic problems, the identification of hosts resistant to H. contortus is another option of control. The aim of this study was to analyse...
Laeticia Kolly et al.
The Journal of allergy and clinical immunology, 131(6), 1635-1643 (2012-09-26)
The exact pathogenesis of the pediatric disorder periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) syndrome is unknown. We hypothesized that PFAPA might be due to dysregulated monocyte IL-1β production linked to genetic variants in proinflammatory genes. Fifteen patients with...
Daniel Brugger et al.
The British journal of nutrition, 121(8), 849-858 (2019-01-30)
The effects of subclinical Zn deficiency on depletion and redistribution of body Zn were studied in weaned piglets. Forty-eight weaned piglets (German-Large-White×Land-Race×Piétrain; 50 % female, 50 % male-castrated; body weight 8·5 (sd 0·27) kg) were fed restrictively (450 g/d) a...
Efstathios P Papadakis et al.
Journal of minimally invasive gynecology, 22(7), 1203-1207 (2015-07-01)
To evaluate the feasibility and impact of levonorgestrel intrauterine system (LNG-IUS) on treatment failure after endometrial ablation (EA) in women with heavy menstrual bleeding (HMB) and dysmenorrhea at 4 years. Cohort study (Canadian Task Force II-2). An academic institution in...
Kirsten Neudoerffer Kangelaris et al.
Chest, 141(5), 1160-1169 (2011-12-31)
Acute lung injury (ALI) mortality is increased among African Americans compared with Americans of European descent, and genetic factors may be involved. A functional T-46C polymorphism (rs2814778) in the promoter region of Duffy antigen/receptor for chemokines (Darc) gene, present almost...
Bryan M H Keng et al.
Journal of the American Geriatrics Society, 67(12), 2568-2573 (2019-08-17)
The link between skeletal muscle and heart disease remains intriguing. It is unknown how skeletal muscle may be associated with aspects of myocardial structure and function, particularly in the presence of aging-related sarcopenia. We hypothesize that among aging adults with...
Liesbeth V Maggiotto et al.
Molecular genetics and metabolism, 127(2), 166-173 (2019-06-12)
We examined Red Blood Cell (RBC) Glucose Transporter isoform 1 (GLUT1) and White Blood Cell (WBC) Glucose Transporter isoform 3 (GLUT3) protein concentrations to assess their potential as surrogate biomarkers for the presence of hypoxic-ischemic encephalopathy (HIE) and response to...
Sally N Adebamowo et al.
International journal of stroke : official journal of the International Stroke Society, 10(7), 1093-1100 (2015-06-06)
Intakes of magnesium, potassium, and calcium have been inversely associated with the incidence of hypertension, a known risk factor for stroke. However, only a few studies have examined intakes of these cations in relation to risk of stroke. The aim...
Saghi Riahizadeh et al.
Helicobacter, 15(6), 497-504 (2010-11-16)
Furazolidone is a much cheaper drug with a very low resistance against Helicobacter pylori compared to clarithromycin. We aim to evaluate safety and efficacy of a sequential furazolidone-based regimen versus clarithromycin-based therapy in H. pylori eradication for ulcer disease. Patients...
Gian Luca Di Tanna et al.
The Lancet. Global health, 7(2), e191-e199 (2019-01-27)
Xpert MTB/RIF, the most widely used automated nucleic acid amplification test for tuberculosis, is available in more than 130 countries. Although diagnostic accuracy is well documented, anticipated improvements in patient outcomes have not been clearly identified. We performed an individual...
Karim Fizazi et al.
The Lancet. Oncology, 15(13), 1442-1450 (2014-12-03)
Poor prognosis germ-cell tumours are only cured in about half of patients. We aimed to assess whether treatment intensification based on an early tumour marker decline will improve progression-free survival for patients with germ-cell tumours. In this phase 3, multicentre...

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