Showing 1-30 of 1868 results for "88071"
Jing-Kun Yan et al.
Carbohydrate polymers, 176, 11-18 (2017-09-21)
A novel proteoglycan, named CFPS-11, was isolated from Corbicula fluminea, which is a food source of freshwater bivalve mollusk. CFPS-11 had an average molecular weight of 807.7kDa and consisted of d-glucose and d-glucosamine in a molar ratio of 12.2:1.0. The...
Lamiaa M A Ali et al.
Life sciences, 245, 117361-117361 (2020-02-01)
Evaluation of the anti-diabetic effect of superparamagnetic iron oxide nanoparticles (SPIONs) on Type 2 diabetic rats and compared their effect to metformin treatment. Diabetic rats were treated with different doses of nanoparticles one time per week for 4 weeks. Fasting blood...
Katharina R Beck et al.
The Journal of steroid biochemistry and molecular biology, 190, 19-28 (2019-03-25)
Oxysterols are cholesterol metabolites derived through either autoxidation or enzymatic processes. They consist of a large family of bioactive lipids that have been associated with the progression of multiple pathologies. In order to unravel (patho-)physiological mechanisms involving oxysterols, it is...
Arman Jafari et al.
Journal of the mechanical behavior of biomedical materials, 88, 395-405 (2018-09-14)
This study focuses on the evaluation and modification of polyurethane (PU) membranes containing organic and inorganic nanoparticles for potential use as a wound dressing. For the purpose of PU nanocomposite preparation, chitosan (CS) was converted into nanoparticles by the ionic-gelation...
Yuya Nakashima et al.
Free radical biology & medicine, 108, 300-310 (2017-03-21)
Skin damage from exposure to sunlight induces aging-like changes in appearance and is attributed to the ultraviolet (UV) component of light. Photosensitized production of reactive oxygen species (ROS) by UVA light is widely accepted to contribute to skin damage and...
Kumar Sangeetha Selvan et al.
Materials science & engineering. C, Materials for biological applications, 98, 657-665 (2019-03-01)
A novel sensor of a square wave anodic stripping voltammetric (SWASV) determination of Pb(II) and Cd(II) with a Multiwall carbon nanotube MWCNT/(H2bpabza) novel tetradentate carboxamide ligand modified electrode is reported. The ligand was synthesized and prepared by the condensation of...
Bushra T ALQuadeib et al.
International journal of nanomedicine, 15, 857-869 (2020-02-28)
Lidocaine (LID) is a local anesthetic that is administered either by injection and/or a topical/transdermal route. However, there is a current need to develop efficacious methods for the oral delivery of LID with optimized bioavailability. We developed oral LID biodegradable...
Wenjie Wang et al.
Carbohydrate polymers, 157, 1246-1253 (2016-12-19)
For improving stability of fruit anthocyanins (ACN), this study investigated the use of cellulose nanocrystal (CNC) as a macroion crosslinking agent to develop blueberry anthocyanin extract (BB)-loaded chitosan (CH)-CNC microcapsules, and compared with CH-sodium tripolyphosphate (TPP) ones. The yield of...
Hien Minh Nguyen et al.
Natural product research, 33(8), 1175-1181 (2018-04-24)
A new sterol, langcosterol A (1), together with two known sterols 2 and 3, were isolated from the marine sponge Xestospongia testudinaria collected in Vietnam. Their chemical structures were elucidated on the basis of extensive spectroscopic analyses and comparisons with...
Ena Gupta et al.
Pharmacognosy magazine, 13(51), 345-350 (2017-08-26)
This study aimed to investigate the cytotoxicity, apoptosis induction, and mechanism of action of steviol on human breast cancer cells (Michigan Cancer Foundation-7 [MCF-7]). Sulforhodamine-B assay was performed to analyze cytotoxic potential of Steviol whereas flow cytometer was used to...
Natascha Schmidt et al.
Environmental science & technology, 53(13), 7513-7521 (2019-06-28)
The release of emerging organic contaminants is identified among the most critical hazards to the marine environment, and plastic additives have received growing attention due to their worldwide distribution and potential deleterious effects. Here, we report dissolved surface water concentrations...
Jana Liskova et al.
Microscopy research and technique, 80(8), 936-942 (2017-04-30)
Collagen often acts as an extracellular and intracellular marker for in vitro experiments, and its quality defines tissue constructs. To validate collagen detection techniques, cardiac valve interstitial cells were isolated from pigs and cultured under two different conditions; with and...
Marie-Estelle Losfeld et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(10), 4623-4635 (2017-07-07)
To study how the interaction between
Hoi Yee Chu et al.
BMC evolutionary biology, 18(1), 54-54 (2018-04-21)
Recombination is widespread across the tree of life, because it helps purge deleterious mutations and creates novel adaptive traits. In prokaryotes, it often takes the form of horizontal gene transfer from a donor to a recipient bacterium. While such transfer...
Giovanni K Zorzi et al.
Colloids and surfaces. B, Biointerfaces, 135, 533-541 (2015-08-25)
Cationized polymers have been proposed as transfection agents for gene therapy. The present work aims to improve the understanding of the potential use of different cationized proteins (atelocollagen, albumin and gelatin) as nanoparticle components and to investigate the possibility of...
R S Leena et al.
Colloids and surfaces. B, Biointerfaces, 158, 308-318 (2017-07-16)
Silibinin is a plant derived flavonolignan known for its multiple biological properties, but its role in the promotion of bone formation has not yet been well studied. Moreover, the delivery of Silibinin is hindered by its complex hydrophobic nature, which...
Lindsey K Ly et al.
The Journal of steroid biochemistry and molecular biology, 199, 105567-105567 (2019-12-25)
The adrenal gland has traditionally been viewed as a source of "weak androgens"; however, emerging evidence indicates 11-oxy-androgens of adrenal origin are metabolized in peripheral tissues to potent androgens. Also emerging is the role of gut bacteria in the conversion...
Shuai Zhou et al.
Analytical chemistry, 90(13), 7982-7988 (2018-06-05)
In this paper, novel calcium-selective nanospheres incorporating Pluronic F127 and (4-carboxybutyl) triphenylphosphonium bromide (TPP) as shell layers were designed to monitor the level of free calcium ion in mitochondria and lysosomes at living cells simultaneously. TPP as a target for...
Maria Abdul Ghafoor Raja et al.
PloS one, 10(6), e0128963-e0128963 (2015-06-13)
Chitosan (CS) nanoparticles have been extensively studied for siRNA delivery; however, their stability and efficacy are highly dependent on the types of cross-linker used. To address this issue, three common cross-linkers; tripolyphosphate (TPP), dextran sulphate (DS) and poly-D-glutamic acid (PGA)...
Lobke Bastings et al.
Journal of assisted reproduction and genetics, 33(12), 1605-1614 (2016-10-08)
Different protocols are being used worldwide for the cryopreservation of human ovarian tissue for fertility preservation purposes. The efficiency and efficacy of the majority of these protocols has not been extensively evaluated, possibly resulting in sub-optimally cryopreserved ovarian tissue. To...
Franziska Gerwien et al.
Frontiers in microbiology, 8, 1055-1055 (2017-06-24)
Iron acquisition is a crucial virulence determinant for many bacteria and fungi, including the opportunistic fungal pathogens
Renjun Ma et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 18(20), 2881-2889 (2017-08-24)
Modulating the heterogeneous microenvironment in room-temperature ionic liquids (RTILs) by external stimuli is an important approach for understanding and designing external field-induced chemical reactions in natural and applied systems. Here, we report for the first time the redistribution of oxygen...
Jiangtao Li et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 234, 58-67 (2019-05-12)
Although previous studies have shown that salinity exposure affects shrimp respiration, little is known of the properties and variation of anaerobic and aerobic metabolism in tissues, and in particular of the relationship between energy metabolism and shrimp locomotion. To examine...
Brijesh Shah et al.
International journal of biological macromolecules, 89, 206-218 (2016-05-01)
The objective of the present investigation was to optimize and develop quetiapine fumarate (QF) loaded chitosan nanoparticles (QF-NP) by ionic gelation method using Box-Behnken design. Three independent variables viz., X1-Concentration of chitosan, X2-Concentration of sodium tripolyphosphate and X3-Volume of sodium...
Alexander Pompermayer Jardine et al.
Clinical oral investigations, 23(3), 1367-1372 (2018-07-20)
To assess the viability of multispecies microcosm biofilm after contact with NeoMTA Plus, Biodentine, and MTA Angelus. Fifty-four human dentin blocks (4 × 5 × 4 mm) were allocated to Hawley retainers, worn by six volunteers for 72 h. The blocks were then individually incubated in...
Patrick Schaub et al.
Journal of agricultural and food chemistry, 65(31), 6588-6598 (2017-07-14)
Provitamin A biofortification, the provision of provitamin A carotenoids through agriculture, is regarded as an effective and sustainable intervention to defeat vitamin A deficiency, representing a global health problem. This food-based intervention has been questioned in conjunction with negative outcomes...
Un-Jung Kim et al.
Environmental science & technology, 51(14), 7872-7880 (2017-06-13)
The occurrence and fate of 14 triester organophosphate flame retardants (OPFRs) and plasticizers and their two diester metabolites were investigated in a wastewater treatment plant (WWTP) in the Albany area of New York State. All target OPFRs were found in...
Jieyao Yuan et al.
Journal of animal science and biotechnology, 11, 49-49 (2020-05-16)
The benefits of using the oxidized oils from rendering and recycling as an economic source of lipids and energy in animal feed always coexist with the concerns that diverse degradation products in these oxidized oils can negatively affect animal health...
Petr Masner et al.
Environmental science and pollution research international, 24(4), 3748-3758 (2016-11-27)
The present study demonstrates development of a rapid testing protocol based on a small portable luminometer using flash kinetic assessment of bacterial bioluminescence. The laboratory comparisons based on six model organic toxicants and two metals showed significant correlations between responses...
Kelly G Bryant et al.
Oncotarget, 8(68), 112184-112198 (2018-01-20)
Reprogramming of mitochondrial functions sustains tumor growth and may provide therapeutic opportunities. Here, we targeted the protein folding environment in mitochondria by coupling a purine-based inhibitor of the molecular chaperone Heat Shock Protein-90 (Hsp90), PU-H71 to the mitochondrial-targeting moiety, triphenylphosphonium...

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