Showing 1-30 of 51 results for "

95220

"
Makoto Makishima et al.
Science (New York, N.Y.), 296(5571), 1313-1316 (2002-05-23)
The vitamin D receptor (VDR) mediates the effects of the calcemic hormone 1alpha,25-dihydroxyvitamin D3 [1,25(OH)2D3]. We show that VDR also functions as a receptor for the secondary bile acid lithocholic acid (LCA), which is hepatotoxic and a potential enteric carcinogen....
Natasha Khazai et al.
Current rheumatology reports, 10(2), 110-117 (2008-05-08)
Vitamin D is known for its role in calcium homeostasis for optimal skeletal health. It was previously believed that only elderly or hospitalized patients were at risk for vitamin D insufficiency, but many people in the general US population have...
Lisa A Houghton et al.
The American journal of clinical nutrition, 84(4), 694-697 (2006-10-07)
Supplemental vitamin D is available in 2 distinct forms: ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Pharmacopoeias have officially regarded these 2 forms as equivalent and interchangeable, yet this presumption of equivalence is based on studies of rickets prevention in...
Alexander Ströhle et al.
Inflammation & allergy drug targets, 10(1), 54-63 (2010-12-28)
As elements of the antioxidant system, cofactors of enzymes, components of transcription factors, and epigenetic modulators, micronutrients, such as vitamins and trace elements, influence various metabolic processes that are directly associated with immune functions. Specifically, the vitamins C and D...
Shaochun Bai et al.
Current opinion in nephrology and hypertension, 15(4), 381-385 (2006-06-16)
In idiopathic hypercalciuria, patients have increased intestinal Ca absorption and decreased renal Ca reabsorption, with either elevated or normal serum levels of 1,25-dihydroxyvitamin D. As 1,25-dihydroxyvitamin D exerts its biologic effects through interactions with the vitamin D receptor, we examine...
Denise R. Ferrier
Biochemistry, 386-386 (2013)
R Jorde et al.
European journal of endocrinology, 152(1), 39-45 (2005-03-15)
Smoking is associated with reduced bone density and calcium absorption, and reduced serum levels of vitamin D. A compensatory increase in serum parathyroid hormone (PTH) would therefore be expected as a result of an altered calcium balance. However, reports on...
Daniela Max et al.
Molecular nutrition & food research, 58(2), 343-352 (2013-08-22)
Epidemiologic data reveal associations between low serum concentrations of 25-hydroxyvitamin D (25(OH)D) and higher risk of falls and muscle weakness. Fetal stage is critical for the development of skeletal muscle, but little information is available on the impact of maternal...
Veena L Venkat et al.
Journal of pediatric gastroenterology and nutrition, 59(6), 702-707 (2014-11-25)
Fat-soluble vitamin (FSV) deficiency is a well-recognized consequence of cholestatic liver disease and reduced intestinal intraluminal bile acid. We hypothesized that serum bile acid (SBA) would predict biochemical FSV deficiency better than serum total bilirubin (TB) level in infants with...
The influence of the menstruum on the effectiveness of vitamin D obtained from the livers of the percomorphi order of fish
Lewis JM
The Journal of Pediatrics, 14(5), 559-569 (1939)
Jack C Cappozzo et al.
Journal of dairy science, 98(8), 5068-5079 (2015-06-01)
As a result of growing interest to nonthermal processing of milk, the purpose of this study was to characterize the chemical changes in raw milk composition after exposure to a new nonthermal turbulent flow UV process, conventional thermal pasteurization process...
Kaori Taguchi et al.
Journal of chromatography. A, 1362, 270-277 (2014-09-10)
Chromatography techniques usually use a single state in the mobile phase, such as liquid, gas, or supercritical fluid. Chromatographers manage one of these techniques for their purpose but are sometimes required to use multiple methods, or even worse, multiple techniques...
Amanda J Samanek et al.
The Medical journal of Australia, 184(7), 338-341 (2006-04-06)
To examine the influence of geographical and seasonal factors on duration of solar ultraviolet (UV) radiation exposure of skin to produce recommended vitamin D levels without producing erythema. An ecological study using daily Ultraviolet Index (UVI) data collected in major...
B L Salle et al.
The American journal of clinical nutrition, 71(5 Suppl), 1317S-1324S (2000-05-09)
During pregnancy, maternal serum concentrations of 25-hydroxyvitamin D, the circulating form of vitamin D, correlate with dietary vitamin D intake. Maternal serum concentrations of 1,25-dihydroxyvitamin D, the hormonal circulating and active form of vitamin D, are elevated during pregnancy; 1,25-dihydroxyvitamin...
Lilian Cuppari et al.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 21(1), 113-116 (2011-01-05)
Vitamin D was discovered and had its chemical structure described in the early years of the last century. Although classified as a nutrient because it was found in small quantities in butter, it soon became clear that exposure of skin...
G S Hiremath et al.
Multiple sclerosis (Houndmills, Basingstoke, England), 15(6), 735-740 (2009-04-23)
Vitamin D is important for bone health and immune regulation, and has been shown to be low in multiple sclerosis (MS). We sought to determine the effect of over the counter low dose cholecalciferol (LDC) and high dose ergocalciferol (HDE)...
Jim Bartley
Expert review of anti-infective therapy, 8(12), 1359-1369 (2010-12-08)
In the preantibiotic era, TB of the skin was treated successfully with UV light. By the 1920s, pulmonary TB was being treated with regular sun exposure. During the last decade, basic laboratory research into the antimicrobial actions of vitamin D...
G Jones et al.
Physiological reviews, 78(4), 1193-1231 (1998-10-28)
The important reactions that occur to the vitamin D molecule and the important reactions involved in the expression of the final active form of vitamin D are reviewed in a critical manner. After an overview of the metabolism of vitamin...
H A Bischoff-Ferrari et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 19(2), 265-269 (2004-02-19)
Intracellular 1,25-dihydroxyvitamin D receptor (VDR) is expressed in human skeletal muscle tissue. However, it is unknown whether VDR expression in vivo is related to age or vitamin D status, or whether VDR expression differs between skeletal muscle groups. We investigated...
Pentti Tuohimaa et al.
International journal of cancer, 108(1), 104-108 (2003-11-18)
Vitamin D inhibits the development and growth of prostate cancer cells. Epidemiologic results on serum vitamin D levels and prostate cancer risk have, however, been inconsistent. We conducted a longitudinal nested case-control study on Nordic men (Norway, Finland and Sweden)...
H A Bischoff et al.
The Histochemical journal, 33(1), 19-24 (2001-05-16)
Growing evidence suggests that intracellular vitamin D receptors are present in skeletal muscle tissue mediating vitamin D hormone response. The aim of the work reported here was to investigate the in situ expression of 1,25-dihydroxyvitamin D3 receptor in human skeletal...
D B Gomis et al.
Journal of chromatography. A, 891(1), 109-114 (2000-09-22)
The fat-soluble vitamins A, D2, D3, E and K1, retinyl acetate, retinyl palmitate, tocopherol acetate, ergosterol and 7-dehydrocholesterol in milk were separated on a packed reversed-phase fused-silica microcolumn, and determined with UV detection. Conventional liquid chromatographic equipment was adapted for...
Michael P Boyle et al.
American journal of respiratory and critical care medicine, 172(2), 212-217 (2005-04-30)
Treatment guidelines for vitamin D monitoring and supplementation in cystic fibrosis (CF) have recently been developed and published by a consensus committee, but have not been prospectively tested. To use these guidelines to determine the percentage of adults with CF...
Minjun Chen et al.
Drug discovery today, 16(15-16), 697-703 (2011-06-01)
Drug-induced liver injury (DILI) is a leading cause of drugs failing during clinical trials and being withdrawn from the market. Comparative analysis of drugs based on their DILI potential is an effective approach to discover key DILI mechanisms and risk...
Wei-Jie Wu et al.
PloS one, 9(4), e95359-e95359 (2014-04-17)
Response surface methodology (RSM) was used to determine the optimum vitamin D2 synthesis conditions in oyster mushrooms (Pleurotus ostreatus). Ultraviolet B (UV-B) was selected as the most efficient irradiation source for the preliminary experiment, in addition to the levels of...
Sejal Shah et al.
The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 57(1), 19-23 (2015-04-16)
Vitamin D deficiency and cardiometabolic risk factors are common in obese adolescents. Observational studies demonstrate an inverse relationship among serum 25-hydroxyvitamin D (25OHD) and obesity, insulin resistance, and inflammatory cytokines. This pilot study explores if vitamin D supplementation could reduce...
Nirav Shah et al.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 25(4), 362-366 (2005-07-19)
Peritoneal dialysis (PD) patients are at risk for 25(OH) vitamin D deficiency due to effluent loss in addition to traditional risk factors. To measure 25(OH) vitamin D deficiency in prevalent PD patients, to evaluate a replacement dose, and to determine...
Rodrigo O Moreira et al.
Arquivos brasileiros de endocrinologia e metabologia, 48(4), 443-450 (2005-03-12)
Disturbances in Calcium-PTH-Vitamin D axis are frequently associated with chronic liver diseases (CLD). In patients with CLD, a trend toward decreased serum calcium and vitamin D has already been demonstrated with compensatory increases in PTH levels. Even though reduced vitamin...
Dean M Robinson et al.
Treatments in endocrinology, 4(3), 185-186 (2005-05-19)
Paricalcitol (Zemplar) is a synthetic vitamin D2 analog that inhibits the secretion of parathyroid hormone (PTH) through binding to the vitamin D receptor. It is approved in the US and in most European nations for intravenous use in the prevention...
A A Toropov et al.
European journal of medicinal chemistry, 43(4), 714-740 (2007-07-17)
Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and organic compounds of different classes by optimal descriptors. Statistical characteristics of the best model (vitamins) are the...