Showing 1-29 of 29 results for "98-46-4"
R Carella et al.
The American journal of surgical pathology, 25(1), 43-50 (2001-01-06)
Immunohistochemistry provides an important indicator for differential diagnosis between pleural malignant mesothelioma and lung adenocarcinoma, which have complex therapeutic and medicolegal implications. To pinpoint a reliable, restricted panel of markers, the authors evaluated the efficacy of select commercial antibodies in...
R S Solomons et al.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 19(1), 74-80 (2014-12-19)
Early treatment is critical to reducing tuberculous meningitis (TBM) related morbidity and mortality. Diagnosis based on cerebrospinal fluid (CSF) culture is impractical due to slow turnaround times, while microscopy has poor sensitivity. Enhanced detection methods are essential to guide early...
J M Carr et al.
Journal of molecular endocrinology, 13(2), 219-236 (1994-10-01)
Three different molecular mass forms of IGF-binding proteins (IGFBPs) were purified from ovine plasma by IGF-I affinity chromatography and reverse-phase HPLC: a 46 kDa doublet and 29 kDa and 24 kDa forms. Amino-terminal sequence analysis confirmed that these proteins were...
A Franco et al.
Transplantation proceedings, 47(8), 2364-2367 (2015-11-01)
Calcineurin inhibitors (CNI) have failed to improve long-term outcomes in renal transplantation. Anti-proliferative and anti-angiogenic effects of mammalian target of rapamycin inhibitors (m-TOR) without nephrotoxicity could improve long-term survival in selected transplant recipients. We examined the evolution of 98 low-immunological...
W K Sonnenburg et al.
The Journal of biological chemistry, 270(52), 30989-31000 (1995-12-29)
Using a bovine 61-kDa (PDE1A2) calmodulin-stimulated phosphodiesterase (CaM-PDE) cDNA and a bovine lung 59-kDa (PDE1A1) CaM-PDE cDNA reported here, we have identified two new regions within the primary structure of these two related isozymes that are important for regulation by...
F S Kibenge et al.
The Journal of general virology, 81(Pt 1), 143-150 (2000-01-21)
Infectious salmon anaemia virus (ISAV) is a new orthomyxovirus-like virus. Thirteen isolates of ISAV (11 from Canada, one from Norway and one from Scotland) were studied for their replication in the CHSE-214 cell line compared with that in the SHK-1...
Christina R Phares et al.
The American journal of tropical medicine and hygiene, 85(4), 612-615 (2011-10-07)
During May 4, 2007-February 29, 2008, the United States resettled 6,159 refugees from Tanzania. Refugees received pre-departure antimalarial treatment with sulfadoxine-pyrimethamine (SP), partially supervised (three/six doses) artemether-lumefantrine (AL), or fully supervised AL. Thirty-nine malaria cases were detected. Disease incidence was...
C Bosc et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(5), 2125-2130 (1996-03-05)
Nerve cells contain abundant subpopulations of cold-stable microtubules. We have previously isolated a calmodulin-regulated brain protein, STOP (stable tubule-only polypeptide), which reconstitutes microtubule cold stability when added to cold-labile microtubules in vitro. We have now cloned cDNA encoding STOP. We...
Todd W Kelley et al.
American journal of clinical pathology, 128(6), 958-965 (2007-11-21)
We studied the prognostic importance of tumor-infiltrating regulatory T lymphocytes (Tregs) and cytotoxic T/NK lymphocytes (CTLs) in 98 diagnostic biopsy specimens from patients with classical Hodgkin lymphoma (cHL). Immunohistochemical analysis was performed for FOXP3 to identify Tregs and for granzyme...
David E Lanfear et al.
JAMA, 294(12), 1526-1533 (2005-09-29)
Previous data support an association between polymorphisms of the beta1- and beta2-adrenergic receptors (ADRB1 and ADRB2) and surrogate end points of response to beta-adrenergic blocker therapy. However, no associations between these polymorphisms and mortality have been demonstrated. To evaluate the...
Vicky A Cameron et al.
Hypertension (Dallas, Tex. : 1979), 47(6), 1155-1161 (2006-05-03)
Oxidative stress plays a critical role in the pathogenesis of cardiovascular disease and diabetes. Studies in vascular cells and experimental animals have demonstrated that the angiotensin type-1 receptor (AT1R) contributes to formation of reactive oxygen species by activating nicotinamide-adenine dinucleotide...
Mitsuaki Kitano et al.
Cancer science, 97(6), 478-483 (2006-06-01)
Expression of TGF-alpha during promotion of neoplastic development from GST-P-positive foci in rat chemical hepatocarcinogenesis was investigated. One-hundred male F344 rats were given a single intraperitoneal injection of DEN (200 mg/kg bodyweight) and subjected to two-thirds partial hepatectomy at week...
G W Hutchinson et al.
Veterinary parasitology, 162(3-4), 278-284 (2009-04-21)
The objective was to compare the efficacy against artificially induced 2- and 4-week old early immature triclabendazole-susceptible liver flukes (Fasciola hepatica) of an injectable combination of nitroxynil, clorsulon and ivermectin with oral and pour-on combination formulations containing triclabendazole. Groups of...
Umashankar Vetrivel et al.
Lipids in health and disease, 11, 109-109 (2012-09-05)
Brain-derived neurotrophic factor (BDNF) is a potent neurotrophic factor that is implicated in the regulation of food intake and body weight. Polyunsaturated fatty acids (PUFAs) localised in cell membranes have been shown to alter the levels of BDNF in the...
Qaiser Bashir et al.
The Lancet. Haematology, 6(5), e266-e275 (2019-03-27)
Retrospective studies suggest that conditioning therapy with busulfan plus melphalan could result in longer progression-free survival compared with melphalan alone in patients with multiple myeloma undergoing autologous haemopoietic cell transplantation (auto-HCT). We aimed to test this hypothesis in a randomised...
Monika Sparber-Sauer et al.
Pediatric blood & cancer, 65(12), e27405-e27405 (2018-08-21)
Patients with metastatic alveolar soft-part sarcoma (ASPS) are known to have a very poor prognosis. Little is known about best treatment of primary metastatic disease (MD) or relapsed metastatic disease (rMD). Patients with localized disease (LD), primary MD, and metastatic...
Martina Montagnana et al.
Journal of clinical laboratory analysis, 23(5), 331-335 (2009-09-24)
Although CA125 is the most widely used cancer marker in the diagnostic approach of pelvic masses in women, its clinical usefulness is limited because it lacks expression of the antigen in the early stages of disease. The human epididymis protein...
Cory M Resnick et al.
Prenatal diagnosis, 38(5), 357-364 (2018-02-21)
Infants with Robin sequence (RS) may present with airway compromise at delivery. Prenatal diagnosis would improve preparation and postnatal care. The purpose of this study was to devise a predictive algorithm for RS based on fetal magnetic resonance imaging (MRI)....
Julian M Stewart et al.
American journal of physiology. Heart and circulatory physiology, 301(3), H704-H711 (2011-06-07)
Models of microgravity are linked to excessive constitutive nitric oxide (NO) synthase (NOS), splanchnic vasodilation, and orthostatic intolerance. Normal-flow postural tachycardia syndrome (POTS) is a form of chronic orthostatic intolerance associated with splanchnic hyperemia. To test the hypothesis that there...
Mathieu Anheim et al.
Archives of neurology, 69(7), 912-916 (2012-03-14)
Friedreich ataxia (FA) is the most frequent type of autosomal recessive cerebellar ataxia, occurring at a mean age of 16 years. Nearly 98% of patients with FA present with homozygous GAA expansions in the FXN gene. The remaining patients are...
Jérôme Verine et al.
PloS one, 5(4), e10421-e10421 (2010-05-11)
We have previously shown that angiopoietin-like 4 (angptl4) mRNA, a hypoxia-inducible gene, is highly expressed in clear cell renal-cell carcinoma (ccRCC), the most common subtype of RCC for which no specific marker is available. We here investigated whether angptl4 mRNA...
C Delaunay
Orthopaedics & traumatology, surgery & research : OTSR, 100(7), 739-744 (2014-09-28)
The effect of hydroxyapatite (HA) coating on the fixation of a cementless femoral stem is discussed, in particular in cases of primary fixation with geometrically stable components. Therefore, we performed a comparative retrospective study of a series of Alloclassic-SL™ stems...
Michaela Artwohl et al.
American journal of physiology. Endocrinology and metabolism, 293(3), E681-E689 (2007-06-15)
Lipoic acid was recently demonstrated to improve endothelial dysfunction or retinopathy not only in rats but also in diabetic patients. We tested the hypothesis that R-(+)-alpha-lipoic acid (LA) directly affects human endothelial cell (EC) function (e.g., apoptosis, proliferation, and protein...
D R Jollie et al.
The Journal of biological chemistry, 266(32), 21853-21863 (1991-11-15)
NAD(+)-coupled formate dehydrogenase has been purified to near-homogeneity from the obligate methanotroph Methylosinus trichosporium OB3b. The inclusion of stabilizing reagents in the purification buffers has resulted in a 3-fold increase in specific activity (98 microM/min/mg; turnover number 600 s-1) and...
Renate B Schnabel et al.
Lancet (London, England), 386(9989), 154-162 (2015-05-12)
Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years. We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation...
Yan-hua Li et al.
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 45(8), 645-651 (2010-11-09)
To study mtDNA, GJB2, GJB3 and determine gene mutation situs and frequency in Uighur and Han people with hereditary nonsyndromic hearing loss, and to compare the differences of gene mutation situs and frequency between Uighur and Han people. Blood samples...
M S Hazelton et al.
Journal of dairy science, 103(12), 11844-11856 (2020-09-29)
Replacement dairy heifers exposed to Mycoplasma bovis as calves may be at risk of future clinical disease and pathogen transmission, both within and between herds; however, little information is available about these risks. We conducted a 2-yr longitudinal (panel) study...
Mikhail Kosiborod et al.
JAMA, 312(21), 2223-2233 (2014-11-18)
Hyperkalemia is a common electrolyte abnormality that may be difficult to manage because of a lack of effective therapies. Sodium zirconium cyclosilicate is a nonabsorbed cation exchanger that selectively binds potassium in the intestine. To evaluate the efficacy and safety...
Yanjun Zhang et al.
The Lancet. Infectious diseases, 21(2), 181-192 (2020-11-21)
With the unprecedented morbidity and mortality associated with the COVID-19 pandemic, a vaccine against COVID-19 is urgently needed. We investigated CoronaVac (Sinovac Life Sciences, Beijing, China), an inactivated vaccine candidate against COVID-19, containing inactivated severe acute respiratory syndrome coronavirus 2...

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