Showing 1-14 of 14 results for "A0420"
Grégoire Couvrat-Desvergnes et al.
The Journal of clinical investigation, 125(12), 4655-4665 (2015-11-10)
Rabbit-generated antithymocyte globulins (ATGs), which target human T cells, are widely used as immunosuppressive agents during treatment of kidney allograft recipients. However, ATGs can induce immune complex diseases, including serum sickness disease (SSD). Rabbit and human IgGs have various antigenic...
The importance of natural IgM: scavenger, protector and regulator
Ehrenstein MR and Notley, Clare A
Nature Reviews: Immunology, 10(11), 778-778 (2010)
C T Hughey et al.
Journal of immunology (Baltimore, Md. : 1950), 161(8), 4091-4097 (1998-10-21)
Secreted IgM is predominantly found as pentameric molecules, but IgM can also be secreted as hexamers by B cell lines. Murine hexamers activate the complement cascade more efficiently than pentamers, but the physiologic significance of hexameric IgM remains unknown. Here...
Sharad P Adekar et al.
Hybridoma (2005), 27(2), 65-69 (2008-07-23)
Affinity-matured human antibodies have demonstrated efficacy as countermeasures for exposure to botulinum neurotoxin (BoNT), which is the cause of the disease botulism category A select bioterror agent. Little is known, however, about the potential role of natural (un-mutated) antibodies in...
Kioa L Wijnsma et al.
Pediatric nephrology (Berlin, Germany), 31(11), 2163-2170 (2016-06-01)
In the majority of pediatric patients, the hemolytic-uremic syndrome (HUS) is caused by an infection with Shiga toxin-producing Escherichia coli (STEC), mostly serotype O157. It is important to discriminate between HUS caused by STEC and complement-mediated HUS (atypical HUS) due...
Xiaoran Wu et al.
Protein & cell, 4(11), 863-871 (2013-11-12)
Graft-versus-host disease (GVHD) is a prevalent and potential complication of hematopoietic stem cell transplantation. An animal model, xenogeneic GVHD (X-GVHD), that mimics accurately the clinical presentation of GVHD would provide a tool for investigating the mechanism involved in disease pathogenesis....
Flávia Fonseca Bagno et al.
Viruses, 12(9) (2020-08-30)
Chikungunya virus (CHIKV) is a mosquito-borne pathogen that causes a disease characterized by the acute onset of fever accompanied by arthralgia and intense joint pain. Clinical similarities and cocirculation of this and other arboviruses in many tropical countries highlight the...
Fully human IgG and IgM antibodies directed against the carcinoembryonic antigen (CEA) Gold 4 epitope and designed for radioimmunotherapy (RIT) of colorectal cancers
Garambois V, et al.
BMC Cancer, 4(1), 75-75 (2004)
The influence of tonsillectomy on total serum antibody levels.
G Pidelaserra Martí et al.
Scandinavian journal of immunology, 80(5), 377-379 (2014-07-22)
Cancer marker detection in human serum with a point-of-care low-cost system
Grosso P, et al.
Sensors and Actuators B, Chemical, 147(2), 475-480 (2010)
Emerging functions of natural IgM and its Fc receptor FCMR in immune homeostasis
Wang H, et al.
Frontiers in Immunology, 7, 99-99 (2016)
Asfia Qureshi et al.
Mycopathologia, 173(5-6), 419-425 (2011-10-06)
We have developed an ELISA to determine the value of anti-glucosylceramide antibody for the prediction of disseminated cryptococcosis in immunocompromised subjects and performed a clinical prospective study at the Medical University of South Carolina. The study enrolled a total of...
Véronique Garambois et al.
BMC cancer, 4, 75-75 (2004-10-19)
Human monoclonal antibodies (MAbs) are needed for colon cancer radioimmunotherapy (RIT) to allow for repeated injections. Carcinoembryonic antigen (CEA) being the reference antigen for immunotargeting of these tumors, we developed human anti-CEA MAbs. XenoMouse-G2 animals were immunized with CEA. Among...
FulmFulminant Amoebic Colitis: Role of the Innate and Adaptive Immune Responses (2012)

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