Showing 1-11 of 11 results for "a3188"
Laura Andreoli et al.
Journal of autoimmunity, 30(1-2), 51-57 (2008-01-15)
Antinucleosome antibodies (anti-NCS) are reported to be highly sensitive and specific for systemic lupus erythematosus (SLE) and to correlate with disease activity. They may appear in early stages of the disease, in particular before anti-dsDNA antibodies, being a potential marker...
Niurys de Castro-Suárez et al.
Journal of clinical pharmacology, 59(6), 863-871 (2019-01-12)
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disease characterized by an overexpression and mislocalization of epidermal growth factor receptor (EGFR) to the apical membranes of cystic epithelial cells. Nimotuzumab is a humanized antibody that recognizes an extracellular domain...
Miryan Margot Sánchez-Jiménez et al.
Heliyon, 6(7), e04393-e04393 (2020-07-21)
Brucella canis, a Gram-negative coccobacilli belonging to the genus Brucellae, is a pathogenic bacterium that can produce infections in dogs and humans. Multiple studies have been carried out to develop diagnostic techniques to detect all zoonotic Brucellae. Diagnosis of Brucella...
Birgit Simell et al.
The Journal of infectious diseases, 186(8), 1106-1114 (2002-10-02)
Mucosal immunity likely plays an important role in the defense against Streptococcus pneumoniae. This study examined whether pneumococcal carriage and acute otitis media induce mucosal antibodies to pneumococcal capsular polysaccharides (Pnc-PSs) of types 1, 6B, 11A, 14, 19F, and 23F....
Sadanori Akita et al.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 12(2), 252-259 (2004-04-17)
To facilitate bone healing in difficult circumstances, and to replace conventional therapeutic modalities, highly purified bone marrow-derived human mesenchymal stem cells (hMSCs) were investigated for induction of their osteogenic lineage upon provision of cytokine cues in vitro and in the...
Christopher P Landowski et al.
PloS one, 10(8), e0134723-e0134723 (2015-08-27)
The filamentous fungus Trichoderma reesei has tremendous capability to secrete proteins. Therefore, it would be an excellent host for producing high levels of therapeutic proteins at low cost. Developing a filamentous fungus to produce sensitive therapeutic proteins requires that protease...
R G Hamilton
Clinical chemistry, 33(10), 1707-1725 (1987-10-01)
Complement activation, cell surface-receptor binding, blocking activity, and possibly placental transfer are among the biologically important functional differences that have been detected between the four human IgG subclasses by use of polyclonal antisera. In 1985, a IUIS/WHO panel of immunologists...
Christian Loch et al.
Journal of pharmaceutical sciences, 103(2), 517-526 (2013-12-07)
Intravitreal injections and drug-loaded implants are current approaches to treat diseases of the posterior eye. To investigate the release of active agents and their distribution in the vitreous body, a new test system was developed that enables a realistic simulation...
M Korkeila et al.
Vaccine, 18(13), 1218-1226 (2000-01-29)
Saliva samples of infants and children immunised with pneumococcal vaccines were analysed for anti-polysaccharide (PS) antibodies against the Streptococcus pneumoniae (Pnc) vaccine serotypes 6B, 14, 19F, and 23F. The children received Pnc conjugate vaccine (1, 3, or 10 micrograms of...
Sönke Detlefsen et al.
Medicine, 97(31), e11641-e11641 (2018-08-05)
The diagnosis of autoimmune pancreatitis (AIP) and its differential diagnosis from pancreatic cancer (PC) can be challenging. In this retrospective study, we aimed to evaluate the value of anti-plasminogen binding peptide (a-PBP), immunoglobulin G4 (IgG4), and anti-carbonic anhydrase-II (a-CA-II), together...
Denise Dorvignit et al.
mAbs, 4(4), 488-496 (2012-06-01)
The CD20 molecule is a non-glycosylated protein expressed mainly on the surface of B lymphocytes. In some pathogenic B cells, it shows an increased expression, thus becoming an attractive target for diagnosis and therapy. Rituximab is a chimeric antibody that...

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