Showing 1-30 of 355 results for "

A3678

"
Tae Hoon Kwon et al.
Molecules and cells, 38(7), 616-623 (2015-05-28)
P2 receptors are membrane-bound receptors for extracellular nucleotides such as ATP and UTP. P2 receptors have been classified as ligand-gated ion channels or P2X receptors and G protein-coupled P2Y receptors. Recently, purinergic signaling has begun to attract attention as a...
Ye Fan et al.
Colloids and surfaces. B, Biointerfaces, 123, 8-14 (2014-09-15)
Unsaturated fatty acid liposomes (Ufasomes) have attracted interests because of the ready availability of unsaturated fatty acids and the simple assembly strategy. However, the colloidal instability of the ufasomes hinders them from applying in the fields of drug delivery and...
Anna Poltronieri et al.
La Medicina del lavoro, 101(6), 403-408 (2010-12-15)
Hairdressers are exposed to irritants and allergenic compounds that may cause contact dermatitis, rhinitis and asthma. In this paper we describe the case of a female, age 33 years, who developed contact dermatitis after 10 years of exposure to ammonium...
Duygu Çimen et al.
Materials science & engineering. C, Materials for biological applications, 56, 318-324 (2015-08-08)
The aim of this study is to prepare megaporous dye-affinity cryogel discs for the purification of plasmid DNA (pDNA) from bacterial lysate. Poly(hydroxyethyl methacrylate) [PHEMA] cryogel discs were produced by free radical polymerization initiated by N,N,N',N'-tetramethylene diamine (TEMED) and ammonium...
Céline Labouesse et al.
Biophysical journal, 108(10), 2437-2447 (2015-05-21)
The mechanical interaction between adherent cells and their substrate relies on the formation of adhesion sites and on the stabilization of contractile acto-myosin bundles, or stress fibers. The shape of the cell and the orientation of these fibers can be...
Ryan C Hill et al.
Molecular & cellular proteomics : MCP, 14(4), 961-973 (2015-02-11)
The use of extracellular matrix (ECM) scaffolds, derived from decellularized tissues for engineered organ generation, holds enormous potential in the field of regenerative medicine. To support organ engineering efforts, we developed a targeted proteomics method to extract and quantify extracellular...
Nor Saadah Mohd Yusof et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 16(4), 775-781 (2015-01-20)
The sonochemical synthesis of gold nanoparticles (GNPs) with different shapes and size distributions by using high-intensity focused ultrasound (HIFU) operating at 463 kHz is reported. GNP formation proceeds through the reduction of Au(3+) to Au(0) by radicals generated by acoustic...
Lucia Cenci et al.
Journal of nanobiotechnology, 13, 51-51 (2015-08-28)
Molecularly imprinted polymer (MIP) technique is a powerful mean to produce tailor made synthetic recognition sites. Here precipitation polymerization was exploited to produce a library of MIP nanoparticles (NPs) targeting the N terminus of the hormone Hepcidin-25, whose serum levels...
Carolina Parra et al.
Journal of nanobiotechnology, 13, 82-82 (2015-11-18)
Biofouling, the colonization of artificial and natural surfaces by unwanted microorganisms, has an important economic impact on a wide range of industries. Low cost antifouling strategies are typically based on biocides which exhibit a negative environmental impact, affecting surrounding organisms...
Alisha Geldert et al.
Scientific reports, 10(1), 8768-8768 (2020-05-31)
Diverse assays spanning from immunohistochemistry (IHC), to microarrays (protein, DNA), to high-throughput screens rely on probe-target hybridization to detect analytes. These large-format 'chips' array numerous hybridization sites across centimeter-scale areas. However, the reactions are prone to intra-assay spatial variation in...
Rongrong Li et al.
International journal of medical sciences, 12(5), 432-440 (2015-06-17)
Intermittent hypoxia preconditioning (IHP) has been shown to protect neurons against ischemic stroke injury. Studying how proteins respond to IHP may identify targets that can help fight stroke. The objective of the present study was to investigate whether mitochondrial dihydrolipoamide...
Avijit Paul et al.
Nanoscale research letters, 10, 140-140 (2015-04-09)
With advancements in nanotechnology, silver has been engineered into a nanometre size and has attracted great research interest for use in the treatment of wounds. Silver nanoparticles (AgNPs) have emerged as a potential alternative to conventional antibiotics because of their...
Gerard H Bode et al.
PloS one, 10(5), e0126136-e0126136 (2015-05-23)
The aim of the current study was to develop a method to detect peptide-linked nanoparticles in blood plasma. A convenient enzyme linked immunosorbent assay (ELISA) was developed for the detection of peptides functionalized with biotin and fluorescein groups. As a...
Nicholas M Bedford et al.
ACS nano, 9(5), 5082-5092 (2015-04-24)
Peptide-enabled synthesis of inorganic nanostructures represents an avenue to access catalytic materials with tunable and optimized properties. This is achieved via peptide complexity and programmability that is missing in traditional ligands for catalytic nanomaterials. Unfortunately, there is limited information available...
Shixuan Chen et al.
Scientific reports, 5, 18104-18104 (2015-12-09)
The purpose of this study was to permit bone marrow mesenchymal stem cells (BMSCs) to reach their full potential in the treatment of chronic wounds. A biocompatible multifunctional crosslinker based temperature sensitive hydrogel was developed to deliver BMSCs, which improve...
Wei-Jiunn Lee et al.
Archives of toxicology, 89(7), 1103-1117 (2014-08-21)
Quercetin is a plant-derived bioflavonoid that was recently shown to have multiple anticancer activities in various solid tumors. Here, novel molecular mechanisms through which quercetin exerts its anticancer effects in acute myeloid leukemia (AML) cells were investigated. Results from Western...
David S Demos et al.
ASAIO journal (American Society for Artificial Internal Organs : 1992), 61(4), 474-479 (2015-04-09)
Donation from uncontrolled circulatory determination of death donors (uDCD) is impractical in United States because of the time needed to organize procurement before irreversible organ damage. Salvaging organs after prolonged warm ischemic time (WIT) may address this limitation. We evaluated...
Efrat Naaman et al.
Scientific reports, 10(1), 20954-20954 (2020-12-03)
Amyloid-β (Aβ), reported as a significant constituent of drusen, was implicated in the pathophysiology of age-related macular degeneration (AMD), yet the identity of the major pathogenic Aβ species in the retina has remained hitherto unclear. Here, we examined the in-vivo retinal...
Liuxing Feng et al.
Analytica chimica acta, 884, 19-25 (2015-06-16)
Species-specific (SS) isotope dilution analysis with gel electrophoresis (GE)-laser ablation (LA)-ICP-MS is a promising technique for the quantification of particular metal-binding proteins in biological samples. However, unavailable isotopically enriched spike and metal losses in GE separation are main limitations for...
George S D Gordon et al.
Journal of biomedical optics, 24(12), 1-13 (2019-12-17)
Phase and polarization of coherent light are highly perturbed by interaction with microstructural changes in premalignant tissue, holding promise for label-free detection of early tumors in endoscopically accessible tissues such as the gastrointestinal tract. Flexible optical multicore fiber (MCF) bundles...
Jeanette Beers et al.
Scientific reports, 5, 11319-11319 (2015-06-13)
Factors limiting the adoption of iPSC technology include the cost of developing lines and the time period that it takes to characterize and bank them, particularly when integration free, feeder free, and Xeno-free components are used. In this manuscript we...
Gerrit Müller et al.
Autophagy, 16(8), 1380-1395 (2019-11-02)
Oxidative stress and Th17 cytokines are important mediators of inflammation. Treatment with beta-adrenoceptor (ADRB) antagonists (beta-blockers) is associated with induction or aggravation of psoriasis-like skin inflammation, yet the underlying mechanisms are poorly understood. Herein, we identify lysosomotropic beta-blockers as critical...
Alison Su et al.
Analytical chemistry, 92(1), 875-883 (2019-11-23)
Thermodynamic partitioning dictates solute loading and release from a hydrogel. Design of drug delivery vehicles, cell and tissue matrices, and immunoassay scaffolds that utilize hydrogel materials is informed by an understanding of the thermodynamic partitioning properties of those hydrogels. We...
Keun-Young Shin et al.
Scientific reports, 5, 13615-13615 (2015-09-05)
Highly omnidirectional and frequency controllable carbon/polyaniline (C/PANI)-based, two- (2D) and three-dimensional (3D) monopole antennas were fabricated using screen-printing and a one-step, dimensionally confined hydrothermal strategy, respectively. Solvated C/PANI was synthesized by low-temperature interfacial polymerization, during which strong π-π interactions between...
Jonas Van Rie et al.
Journal of materials science. Materials in medicine, 26(3), 123-123 (2015-02-19)
The present work describes the development and the evaluation of cryogel-poly-ε-caprolactone combinatory scaffolds for bone tissue engineering. Gelatin was selected as cell-interactive biopolymer to enable the adhesion and the proliferation of mouse calvaria pre-osteoblasts while poly-ε-caprolactone was applied for its...
Yuanyuan Yang et al.
Macromolecular rapid communications, 32(7), 593-597 (2011-03-26)
A novel crosslinked conductive polyaniline (PANI) was prepared by chemically copolymerizing aniline (An) and p-phenylenediamine (PPDA) with triphenylamine (TPA) as crosslinker, using ammonium peroxydisulfate (APS) as an oxidant. The effects of different preparation conditions on the electrical conductivity of polymers...
Fabio Fuselli et al.
Journal of the science of food and agriculture, 95(13), 2757-2762 (2014-11-27)
Prevention of food fraud in the dairy field is a difficult issue for researchers, industries and policy makers, both for commercial and health reasons. Currently, no analytical method allows detection of the addition of bovine whey to water buffalo ricotta...
Yo Murofushi et al.
Molecular immunology, 64(1), 63-75 (2014-12-04)
The radioprotective 105 (RP105)/MD1 complex is a member of the Toll-like receptor (TLR) family. It was reported that RP105/MD1 cooperates with the lipopolysaccharide (LPS) receptor TLR4/MD2 complex and plays a crucial role in the response of immune cells to LPS....
Ji Liu et al.
Nature communications, 11(1), 1071-1071 (2020-02-28)
The adhesion of soft connective tissues (tendons, ligaments, and cartilages) on bones in many animals can maintain high toughness (∽800 J m-2) over millions of cycles of mechanical loads. Such fatigue-resistant adhesion has not been achieved between synthetic hydrogels and engineering materials...
Karin Taylor et al.
mAbs, 7(1), 53-65 (2014-12-20)
There are many design formats for bispecific antibodies (BsAbs), and the best design choice is highly dependent on the final application. Our aim was to engineer BsAbs to target a novel nanocell (EnGeneIC Delivery Vehicle or EDV(TM)nanocell) to the epidermal...