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acetonitrile

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UHPLC Analysis of Cannabinoids on Ascentis Express C18
As the popularity of cannabis-infused products increases, there is a growing need to characterize the type and content of the cannabinoids found in the product. This application demonstrates the ability of the Ascentis Express C18 column to baseline resolve
Determination of Formaldehyde and Acetaldehyde in Air Using DNPH Cartridges and Automated On-Line Desorption Followed by HPLC
Carbonyl compounds react within the DNPH cartridge to form immobilized hydrazones, which can be subjected to automated desorption and HPLC analysis with UV detection.
Isolation and LC-MS Characterization of Illicit Bath Salts in Urine
The combination of ion-exchange SPE with the HILIC HPLC separation provides a novel approach for the testing of problematic bath salt compounds.
Comparison of QuEChERS Products for the Extraction of Planar Pesticides from Spinach
Supel™ QuE Verde combines a novel carbon with zirconia coated silica (Z-Sep+) to provide an optimum balance between planar pesticide recovery and color removal.
Complete Workflow for the Analysis of California List of Pesticides in Cannabis by LC-MS/MS and GC-MS/MS
To show product safety, it is mandatory to test cannabis flowers for the presence of pesticides. In this article, we show a complete workflow for sample preparation and analysis of cannabis for the pesticides registered in California, by LC-MS/MS and
Ion-Exchange SPE Methodology
Normal-Phase Methodology in Solid Phase Extraction Microbiology. In order g003572 for polar retention to occur between the sorbent and the sample, the analyte must be introduced to the SPE device in a non-polar sample or mobile phase environment.
Cannabis Potency Testing: Method Development and Cost Considerations
An overview of gradient HPLC-based analysis of cannabinoids, optimized for key method parameters such as column temperature, mobile phase pH, and methanol as low-cost organic modifier. Learn more here.
How to Maximize Sensitivity in LC-MS
Various measures and options for maximized LC-MS sensitivity and low limit of detection (LOD) are shown on this page. Each and every tip avoids contaminations causing signal suppression, adduct formation, elevated background noise and increased spectrum complexity.
HPLC Analysis of Active Cannabinoid Compounds in Gummy Bear Candy on Ascentis® Express Biphenyl with UV Detection after Extraction
Tetrahydrocannabinolic acid A solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material.
LC/MS Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC
The benefit of HILIC over traditional reversed-phase chromatography is two-fold for both sample introduction and analyte detection. First, the high acetonitrile concentration of HILIC mobile phases allows for direct analysis of precipitated plasma samples without the need for additional sample
radiello® Diffusive Air Sampling Applications - Aldehydes
Learn about radiello® Diffusive Sampling Aldehydes Applications & Methods.
Certified Reference Materials: Synthesis and Characterization of Cocaine N-oxide HCl
Cocaine is one of the most widespread illicit drugs of abuse in the US. Cocaine N-oxide is a metabolite of cocaine formed by cytochrome P-450 mediated oxidation of cocaine.1,2
Improve Pigment Removal and Decrease Matrix Interferences for Pesticide Determination in Oranges Using Supel QuE Z-Sep/C18 QuEChERS Sorbent
The comparison of Supel™ QuE Z-Sep/C18, PSA/C18, and PSA QuEChERS sorbents, in terms of color removal and analyte recovery, is described for the cleanup of oranges prior to pesticide analysis.
Molecularly Imprinted Polymer SPE- Acid NSAIDs from Muscle
A new, successfully developed and validated LC-MS-MS method allowing the extraction of NSAIDs from poultry muscle tissue using Molecularly Imprinted Polymer (MIP) SPE.
Hydrophilic Interaction Liquid Chromatography
An introduction to the HILIC separation technique and an overview of the strategies for developing robust methods for separation of polar and hydrophilic compounds.
LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC
HILIC mobile phases consist of a high composition of acetonitrile, which facilitates the direct analysis of precipitated plasma samples without the need for additional sample solvent exchange.
HPLC Analysis of Protein Standards (1) on BIOshell™ A400 Protein C4
For use as a marker in SDS-PAGE; Albumin from chicken egg white, For use as a marker in SDS-PAGE; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein
HPLC Analysis of Proteins on BIOshell™ A400 Protein C4, Rapid Separation at Elevated Temperature
For use as a marker in SDS-PAGE; lactate dehydrogenase; contaminant; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein
Method Optimization for LC-MS Analysis of Vitamin D Metabolite Critical Pairs in Serum
Using HybridSPE-Phospholipid, Ascentis Express, and Other LC-MS Workflow Components
Method Optimization for LC-MS Analysis of Vitamin D Metabolite Critical Pairs in Serum
Novel sample prep technique coupled with the unique selectivity of the Ascentis Express F5 column enables a fast and simplified bioanalytical method for associated vitamin D metabolites.
Analysis of Remdesivir and other Antiviral Drugs Using LC-MS/MS
We present a fast and robust HPLC-MS/MS method that can be used for Remdesivir and three structural antiviral analogues
Analysis of California Cannabis List of Pesticides, Mycotoxins, and Pyrethrins Using Ascentis® Express Biphenyl Column
Cannabis testing regulations include analysis of purity, potency, and contaminants. Learn more about analysis of cannabis for pesticides, mycotoxins, and pyrethrins registered in California using Ascentis® Express Biphenyl
HPLC Analysis of Caseins on BIOshell™ A400 Protein C4
-casein basis (electrophoresis), lyophilized powder; β-Casein from bovine milk, BioUltra, ≥98% (PAGE)
Investigating Matrix Interference in Analysis of Antiarrhythmic Cardiac Drugs in Plasma
For efficient therapeutic drug monitoring, it is important for clinicians to have access to fast and robust analytical methods for accurate assessment of drug efficacy. Industrial trends toward highly specific LC/MS applications over traditional immunoassay have resulted in the need
Solid Phase Extraction: Reversed-Phase Methodology
Reversed-phase interaction will retain most molecules with hydrophobic character; it is very useful for extracting analytes that are very diverse in structure within the same sample.
UHPLC analysis of Benzoyl peroxide and degradation products on Purospher® STAR RP-18e Hibar® HR
UHPLC analysis of Benzoyl peroxide and degradation products on Purospher®STAR RP-18e Hibar® HR - Conditions & Description
Extraction of Permethrin Pesticides from Spinach Using QuEChERS Methodology with Automated Shaking
Extraction of Permethrin Pesticides from Spinach Using QuEChERS Methodology with Automated Shaking
Improving the Chromatographic Separation of DMB-Labeled Sialic Acids for the Comparison of Biosimilars to Reference Materials
A significantly improved HPLC-fluorescence method for DMB-NANA and -NGNA, and application of this method to compare 2 candidate biosimilar therapeutic proteins to their respective RMs.
A Comparison of Two Solid Phase Extraction Methods for the Analysis of Polyaromatic Hydrocarbons in Butter
Analysis of PAHs in butter can pose a special challenge due to the high fat content and the lipophilic nature of PAHs.
Ascentis® Express UHPLC Columns with 2.0 μm Fused-Core Particles
Ascentis® Express columns with 2.0 μm particles show comparable efficiency at a significantly lower pressure than competitor columns that use smaller particles.
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