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Showing 1-6 of 6 results for "alzheimer_disease"
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Anti-Amyloid β Antibody, clone W0-2 clone WO2, from mouse
Anti-Amyloid β Antibody, clone W0-2
Anti-Amyloid β Antibody, clone W0-2
Product NumberProduct DescriptionSDS
MABN10clone WO2, from mouse
Match Criteria:Product Name
Anti-Amyloid β40 Antibody, clone G2-10 clone G2-10, from mouse
Anti-Amyloid β40 Antibody, clone G2-10
Anti-Amyloid β40 Antibody, clone G2-10
Product NumberProduct DescriptionSDS
MABN11clone G2-10, from mouse
Match Criteria:Product Name
Anti-Amyloid β42 Antibody, clone G2-13 clone G2-13, from mouse
Anti-Amyloid β42 Antibody, clone G2-13
Anti-Amyloid β42 Antibody, clone G2-13
Product NumberProduct DescriptionSDS
MABN13clone G2-13, from mouse
Match Criteria:Product Name
Anti-Amyloid β42 Antibody, clone G2-11 clone G2-11, from mouse
Anti-Amyloid β42 Antibody, clone G2-11
Anti-Amyloid β42 Antibody, clone G2-11
Product NumberProduct DescriptionSDS
MABN12clone G2-11, from mouse
Match Criteria:Product Name
Anti-Collagen XXV α1 antibody produced in rabbit affinity isolated antibody
Anti-Collagen XXV α1 antibody produced in rabbit
Anti-Collagen XXV α1 antibody produced in rabbit
Synonyms:
AMY, Collagen-like Alzheimer amyloid plaque component, Alzheimer disease amyloid-associated protein, CLAC-P, Collagen α-1(XXV) chain
Product NumberClonalityApplicationSpecies ReactivityCitationsSDS
SAB4503368polyclonalELISA, WBhuman, mouse
Match Criteria:Product Name
Anti-APP Antibody, clone 1F22 ZooMAb® Rabbit Monoclonal
Anti-APP Antibody, clone 1F22 ZooMAb® Rabbit Monoclonal
enhanced validationgreener alternative
Synonyms:
ABPP, Protease nexin-II, CVAP, Cerebral vascular amyloid peptide, PN-II, Amyloid-beta precursor protein, PreA4, Alzheimer disease amyloid protein, APPI, Amyloid precursor protein, Amyloid-beta A4 protein
Product NumberClonalityApplicationSpecies ReactivityCitationsSDS
ZRB15161F22, monoclonal
recombinant monoclonal
affinity binding assay, WB, IHC (p)mouse, human, rat
Match Criteria:Product Name
PSEN2
presenilin 2 (Alzheimer disease 4)
Synonyms:
AD3L, AD4, CMD1V, PS2, STM2
Species:
Human PSEN2 (5664), Mouse Psen2 (19165), Rat Psen2 (81751), Zebrafish psen2 (58026), dog PSEN2 (490382), domestic cat PSEN2 (101081693), chicken PSEN2 (374188), Domestic Rabbit PSEN2 (100343671), cow PSEN2 (282010), sheep PSEN2 (101113776)
Summary:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified. [provided by RefSeq, Jul 2008
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