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animal free*

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H Malenovská
Journal of applied microbiology, 117(6), 1810-1819 (2014-09-25)
To make a comparative evaluation of the effects of different stabilizers and freezing rates on structurally different viruses during lyophilization and storage. Two virus strains from each of six animal virus families, including both enveloped and nonenveloped viruses, were lyophilized...
Samia Rourou et al.
Vaccine, 32(24), 2767-2769 (2014-03-04)
IPT-AFM is a proprietary animal component free medium that was developed for rabies virus (strain LP 2061) production in Vero cells. In the present work, we demonstrated the versatility of this medium and its ability to sustain the growth of...
Anup Kumar et al.
Journal of chromatography. A, 1627, 461416-461416 (2020-08-22)
Animal feeds are often reported to be contaminated with chemical residues, and when present above the maximum legal limit, these compounds can cause harmful effects to consumers of animal produce. Thus, animal feed safety is an important regulatory concern. The...
Sonja Axmann et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 32(7), 1089-1098 (2015-04-03)
Since June 2013 the total feed ban of processed animal proteins (PAPs) was partially lifted. Now it is possible to mix fish feed with PAPs from non-ruminants (pig and poultry). To guarantee that fish feed, which contains non-ruminant PAPs, is...
Nathalie Belot et al.
ALTEX, 34(4), 560-564 (2017-04-14)
Skin sensitization is the process by which a substance induces an allergic reaction following skin contact. The process has been described as an adverse outcome pathway (AOP), including several key events, from skin penetration and covalent protein binding, to keratinocyte...
Monika Gibis et al.
Journal of food science, 80(11), C2430-C2439 (2015-10-08)
The impact of precursors such as creatine, creatinine, and glucose on the formation of mutagenic/carcinogenic heterocyclic amines (HAs) were studied in patties of 9 different animal species equally heat treated with a double-plate contact grill. All grilled patties of the...
Rosaria Santoro et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 104(2), 345-356 (2015-03-27)
Glutaraldehyde-fixed pericardium of animal origin is the elective material for the fabrication of bio-prosthetic valves for surgical replacement of insufficient/stenotic cardiac valves. However, the pericardial tissue employed to this aim undergoes severe calcification due to chronic inflammation resulting from a...
Werner J Struss et al.
The Prostate, 77(13), 1356-1365 (2017-08-09)
The vast majority of prostate cancer presents clinically localized to the prostate without evidence of metastasis. Currently, there are several modalities available to treat this particular disease. Despite radical prostatectomy demonstrating a modest prostate cancer specific mortality benefit in the...
Peng Li et al.
Amino acids, 52(4), 523-542 (2020-03-13)
We analyzed the composition of amino acids (AAs) in oligopeptides, proteins, and the free pool, as well as creatine, agmatine, polyamines, carnosine, anserine, and glutathione, in animal- and plant-derived feedstuffs. Ingredients of animal origins were black soldier fly larvae meal...
J R Bertolín et al.
Food chemistry, 257, 182-188 (2018-04-07)
An accurate, fast, economic and simple method to determine carotenoids, tocopherols, retinol and cholesterol in lyophilised samples of ovine milk, muscle and liver and raw samples of fat, which are difficult to lyophilise, is sought. Those analytes have been studied...
Marjory B Brooks et al.
Veterinary clinical pathology, 46(3), 496-507 (2017-08-26)
Thrombin generation assays (TGA) have potential applications as measures of hemostatic balance in animal models. However, variations in plasma processing greatly influence human TGA, and may also impact on the translational value of TGA in animal studies. The purpose of...
Ihab Atallah et al.
Head & neck, 38 Suppl 1, E246-E255 (2014-12-30)
Appropriate animal models are required to test novel therapeutics for head and neck squamous cell carcinoma (HNSCC) such as near-infrared (NIR) imaging-guided surgery. We developed an optimized animal model of orthotopic HNSCC (in female athymic NMRI (Naval Medical Research Institute)...
Alexander Frolov et al.
Journal of neurophysiology, 113(1), 369-379 (2014-10-17)
The nucleus accumbens (NAc) has been shown to play a key role in the brain's response to methylphenidate (MPD). The present study focuses on neuronal recording from this structure. The study postulates that repetitive exposure to the same dose of...
David J Schaeffer et al.
NeuroImage, 193, 126-138 (2019-03-19)
Marmosets are small New World primates that are posited to become an important preclinical animal model for studying intractable human brain diseases. A critical step in the development of marmosets as a viable model for human brain dysfunction is to...
Gen Zhang et al.
Proteomics, 15(22), 3854-3864 (2015-09-01)
Nitric oxide (NO) is a universal signaling molecule and plays a negative role in the metamorphosis of many biphasic organisms. Recently, the NO/cGMP (cyclic guanosine monophosphate) signaling pathway was reported to repress larval settlement in the barnacle Amphibalanus amphitrite. To...
Jutta K H Skau et al.
The American journal of clinical nutrition, 101(4), 742-751 (2015-04-04)
Poor nutritional quality of complementary foods often limits growth. Animal source foods, such as milk or meat, are often unaffordable. Local affordable alternatives are needed. We evaluate the efficacy of 2 newly developed, rice-based complementary food products: WinFood (WF) with...
Aung Soe Lin et al.
mBio, 11(3) (2020-07-02)
The Helicobacter pylori Cag type IV secretion system (T4SS) translocates the effector protein CagA and nonprotein bacterial constituents into host cells. In this study, we infected Mongolian gerbils with an H. pylori strain in which expression of the cagUT operon...
Kelly Bowden-Davies et al.
Proteomics, 15(13), 2342-2349 (2015-03-12)
Divergent selection has created rat phenotypes of high- and low-capacity runners (HCR and LCR, respectively) that have differences in aerobic capacity and correlated traits such as adiposity. We analyzed visceral adipose tissue of HCR and LCR using label-free high-definition MS...
Jonathan E Millar et al.
American journal of respiratory and critical care medicine, 202(3), 383-392 (2020-04-16)
Rationale: Mesenchymal stromal cell (MSC) therapy is a promising intervention for acute respiratory distress syndrome (ARDS), although trials to date have not investigated its use alongside extracorporeal membrane oxygenation (ECMO). Recent preclinical studies have suggested that combining these interventions may...
Xianmin Feng et al.
Anatomical record (Hoboken, N.J. : 2007), 298(8), 1509-1517 (2015-03-15)
Acanthamoeba species are ubiquitous, free-living protozoa that can invade the cornea and result in Acanthamoeba keratitis (AK), a painful progressive sight-threatening corneal disease. Disease progression in current animal models is too rapid to mimic AK in humans accurately. This study...
Bom Soo Kim et al.
Connective tissue research, 56(6), 452-460 (2015-06-16)
Achilles tendinopathy is a common degenerative condition without a definitive treatment. An adequate chronic animal model of Achilles tendinopathy has not yet been developed. The purpose of this study was to evaluate the individual and combined effects of dry needling...
Louise Roberts et al.
Biology open, 8(7) (2019-07-12)
Chemical cues and signals enable animals to sense their surroundings over vast distances and find key resources, like food and shelter. However, the use of chemosensory information may be impaired in aquatic habitats by anthropogenic activities, which produce both water-borne...
Takeshi Yanagisawa et al.
Stroke, 51(10), 3083-3094 (2020-09-12)
Intracranial aneurysm formation and rupture risk are, in part, determined by genetic factors and sex. To examine their role, we compared 3 mouse strains commonly used in cerebrovascular studies in a model of intracranial aneurysm formation and rupture. Intracranial aneurysms...
Joanna Nynca et al.
Proteomics, 15(15), 2643-2654 (2015-03-18)
The aim of this study was to detect cryopreservation-induced alterations in the protein composition of rainbow trout semen using two independent methods 1DE SDS-PAGE prefractionation combined with LC-MS/MS and 2D difference gel electrophoresis followed by MALDI-TOF/TOF identification. Here, we show...
Jonathan L Falconer et al.
International journal of pharmaceutics, 498(1-2), 187-194 (2015-12-26)
Ballistic delivery capability is essential to delivering vaccines and other therapeutics effectively to both livestock and wildlife in many global scenarios. Here, lyophilized poly(ethylene glycol) (PEG)-glycolide dimethacrylate crosslinked but degradable hydrogels were assessed as payload vehicles to protect and deliver...
Ketamine-medetomidine regimen for chemical immobilisation of free-ranging chimpanzees (Pan troglodytes schweinfurthii) in Uganda.
D Hyeroba et al.
The Veterinary record, 172(18), 475-475 (2013-04-02)
Joaquín Valdés et al.
ALTEX, 33(4), 459-464 (2016-11-04)
Diabetic retinopathy (DR) is a major cause of vision loss and one of the most common and debilitating complications of diabetes. Research to prevent DR is hindered by a lack of experimental model systems that faithfully reproduce the disease pathology...
Mária Lódi et al.
Journal of translational medicine, 18(1), 470-470 (2020-12-11)
Cardiomyopathy is a common side effect of doxorubicin (DOX) chemotherapy. Despite intensive research efforts in the field, there is still no evidence available for routine cardioprotective prophylaxis to prevent cardiotoxicity in the majority of oncological patients at low risk of...
C-Y Kao et al.
The European journal of neuroscience, 41(9), 1139-1148 (2015-02-28)
This study measured changes in brain extracellular norepinephrine (NE) and free corticosterone (CORT) levels in a mouse model of post-traumatic stress disorder and related them to hyperarousal and fear memory retention. To this end, microdialysis in the medial prefrontal cortex...
Ashling Holland et al.
Proteomics, 15(13), 2318-2331 (2015-03-05)
Proteomic profiling plays a decisive role in the identification of novel biomarkers of muscular dystrophy and the elucidation of new pathobiochemical mechanisms that underlie progressive muscle wasting. Building on the findings of recent comparative analyses of tissue samples and body...
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