Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 63(1), 154-159 (2005-12-14)
Pr(III) and Nd(III) are hard acceptors in HSAB (hard and soft acid base) sense and hence are known to exhibit practically a little affinity towards electrons. At the same time these metal ions show strong preference for oxygen donor chelating...
A highly efficient and flexible synthesis of substituted carbazoles by rhodium?catalyzed inter?and intramolecular alkyne cyclotrimerizations.
Witulski B and Alayrac C
Angewandte Chemie (International Edition in English), 114(17), 3415-3418 (2002)
Enantioselective total synthesis of bistramide A.
Crimmins M T and DeBaillie A C
Journal of the American Chemical Society, 128(15), 4936-4937 (2006)
Solid state nuclear magnetic resonance, 21(1-2), 86-104 (2002-04-13)
The alkynyl carbon chemical shift (CS) tensors for 2-butyne-1,4-diol are reported, based on analyses of the carbon-13 NMR spectra of stationary-powder and slow magic-angle spinning (MAS) samples for which the alkynyl carbon nuclei are enriched in 13C. NMR spectra of...
Total synthesis of (?)-amphidinolide P.
Williams D R, et al.
Organic Letters, 2(7), 945-948 (2000)
Irreversible inactivation of the flavoenzyme alcohol, oxidase with acetylenic alcohols.
C S Nichols et al.
Biochemical and biophysical research communications, 97(1), 216-221 (1980-11-17)
Allergic contact dermatitis from 2-butin-1,4-diol.
V Blaschke et al.
Allergy, 56(3), 264-265 (2001-03-17)
Synthesis of silafluorenes by iridium-catalyzed [2+ 2+ 2] cycloaddition of silicon-bridged diynes with alkynes.
Derived No Effect Level (DNEL(inh)) has been set for occupational exposure to but-2-yno-1,4-diol according to REACH principles. Maximum allowable concentration (MAC) and DNEL(inh) have been compared. Experimental data from two inhalation studies on rats and three oral studies have been...
Journal of applied toxicology : JAT, 12(2), 117-122 (1992-04-01)
2-Butyne-1,4-diol was given to male and female Wistar Imp:DAK rats by oral gavage for 28 consecutive days in daily doses of 1, 10 or 50 mg kg-1 day-1. After 28 days all animals were necropsied. Blood samples were obtained and...
The Journal of organic chemistry, 73(4), 1605-1607 (2008-01-17)
The conversion of 2-butyn-1,4-diol to (Z)-2,4-diiodobut-2-en-1-ol proceeded efficiently using in situ generated trimethylsilyl iodide. Coupling with Grignard reagents and other nucleophiles delivered (2Z)-2-iodo allylic alcohols. The geometry of the products was established by nOe.
But-2-yne-1,4 diol, primary gloss improver and contact sensitizer in a nickel plating bath.
Journal of applied toxicology : JAT, 12(2), 113-115 (1992-04-01)
Acute toxicity of 2-butyne-1,4-diol (BYD) was evaluated in laboratory animals. The evaluation involved acute oral and dermal toxicity in rats, dermal and ocular irritation in rabbits and skin sensitization in guinea pigs. The oral LD50 values for BYD were 132...
Homologation method for preparation of substituted pentacenes and naphthacenes.
Takahashi T, et al.
The Journal of Organic Chemistry, 71(21), 7967-7977 (2006)
Developmental toxicity of 2-butin-1,4-diol was determined in groups of 18-22 pregnant Wistar rats at dose levels of 10, 40 and 80 mg/kg bw/day administered by gavage from days 6 to 15 pc. At 80 mg/kg bw/day food consumption and maternal...
Morpholine- and bis(2-methoxyethyl)amine-substituted 1,3,5-triazine derivatives containing an alkoxy-o-carborane in the 6-position of the triazine ring were successfully synthesized. The molecular structures of the methoxy- and ethoxy-o-carboranyl-1,3,5-triazines were established by X-ray crystallography. In vitro studies showed that the methylene bridged morpholine-...
We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.