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C1791

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R Intartaglia et al.
Physical chemistry chemical physics : PCCP, 15(9), 3075-3082 (2012-12-01)
A picosecond laser ablation approach has been developed for the synthesis of ligand-free AuAg bimetallic NPs where the relative amount of Ag is controlled in situ through a laser shielding effect. Various measurements, such as optical spectroscopy, transmission electron microscopy...
Estelle Rousselet et al.
Journal of visualized experiments : JoVE, (69)(69), doi:10-doi:10 (2012-11-22)
Stroke is the third cause of mortality and the leading cause of disability in the World. Ischemic stroke accounts for approximately 80% of all strokes. However, the thrombolytic tissue plasminogen activator (tPA) is the only treatment of acute ischemic stroke...
Mario Villa González et al.
Glia, 68(12), 2471-2485 (2020-06-10)
Ischemic stroke is a major cause of death and the first leading cause of long-term disability worldwide. The only therapeutic strategy available to date is reperfusion and not all the patients are suitable for this treatment. Blood flow blockage or...
Derin Birch et al.
Pediatric research, 76(4), 334-340 (2014-07-09)
Hypoxic-ischemic injury (HI) to preterm brain results in white matter loss. The endogenous oligodendroglial response to perinatal HI is characterized by increased oligodendroglial progenitor cells (OPCs). MicroRNAs (miRs) are important post-transcriptional regulators of gene expression, and a few miRs have...
Yelena Golubeva et al.
Methods in molecular biology (Clifton, N.J.), 931, 213-257 (2012-10-03)
Laser capture microdissection (LCM) allows the precise procurement of enriched cell populations from a heterogeneous tissue, or live cell culture, under direct microscopic visualization. Histologically enriched cell populations can be procured by harvesting cells of interest directly or isolating specific...
Erina Hara et al.
PloS one, 7(1), e29457-e29457 (2012-01-13)
Spoken language and learned song are complex communication behaviors found in only a few species, including humans and three groups of distantly related birds--songbirds, parrots, and hummingbirds. Despite their large phylogenetic distances, these vocal learners show convergent behaviors and associated...
C A Smith et al.
Neuroscience, 193, 100-108 (2011-07-26)
The distribution of CA3 hippocampal axonal terminal fields undergo a period of widespread connectivity-based changes in the early postnatal stages of life. The purpose of the current study was to examine the effect of acute phthalate exposure during this period...
Priscilla Hirst et al.
Neural plasticity, 2012, 197264-197264 (2012-07-14)
Recent studies suggest that exposure to only one component of audiovisual events can lead to cross-modal cortical activation. However, it is not certain whether such crossmodal recruitment can occur in the absence of explicit conditioning, semantic factors, or long-term associations....
Sung In Cho et al.
Bioelectromagnetics, 33(7), 568-574 (2012-04-13)
Our previous study has shown that an extremely low-frequency magnetic field (ELF-MF) induces nitric oxide (NO) synthesis by Ca(2+) -dependent NO synthase (NOS) in rat brain. The present study was designed to confirm that ELF-MF affects neuronal NOS (nNOS) in...
Bing Chun Yan et al.
Journal of the neurological sciences, 303(1-2), 100-108 (2011-02-01)
Circulating leptin crosses blood-brain barrier to provide control of feeding behavior and energy balance. We investigated changes in leptin and leptin receptor (ObR) in the gerbil hippocampal CA1 region (CA1) after transient cerebral ischemia, and examined effects of leptin on...
Sébastien Desgent et al.
PloS one, 7(8), e42622-e42622 (2012-08-11)
During development, the risk of developing mesial temporal lobe epilepsy (MTLE) increases when the developing brain is exposed to more than one insult in early life. Early life insults include abnormalities of cortical development, hypoxic-ischemic injury and prolonged febrile seizures....
Shailaja Kesaraju et al.
Journal of neurochemistry, 109(5), 1413-1426 (2009-05-30)
Freshwater turtles survive prolonged anoxia and reoxygenation without overt brain damage by well-described physiological processes, but little work has been done to investigate the molecular changes associated with anoxic survival. We examined stress proteins and apoptotic regulators in the turtle...
D Marcellino et al.
Neuroscience, 226, 324-347 (2012-09-19)
The anterior and rostral paracapsular intercalated islands (AIC and PIC, respectively) were studied in the context of the amygdaloid modulation of fear/anxiety using horizontal sections. The structural analysis carried out using silver-impregnated specimens revealed that the AIC is composed of...
George Dragoi et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(22), 9100-9105 (2013-05-15)
The activity of ensembles of hippocampal place cells represents a hallmark of an animal's spatial experience. The neuronal mechanisms that enable the rapid expression of novel place cell sequences are not entirely understood. Here we report that during sleep or...
Kelly A Dunham et al.
Journal of neurotrauma, 27(11), 2091-2106 (2010-11-23)
Most experimental models of spinal cord injury (SCI) in rodents induce damage in the thoracic cord and subsequently examine hindlimb function as an indicator of recovery. In these models, functional recovery is most attributable to white-matter preservation and is less...
Stefan Jean-Pierre Haas et al.
Journal of anatomy, 212(1), 19-30 (2007-11-27)
Neural progenitor cell grafting is a promising therapeutic option in the treatment of Parkinson's disease. In previous experiments we grafted temperature-sensitive immortalized CSM14.1 cells, derived from the ventral mesencephalon of E14-rats, bilaterally in the caudate putamen of adult hemiparkinsonian rats....
Dae Young Yoo et al.
Cellular and molecular neurobiology, 31(5), 729-736 (2011-03-02)
In this study, we observed neuroblast differentiation in the somatosensory cortex (SSC) and hippocampal CA1 region (CA1), which is vulnerable to oxidative stress, of the mouse at various early postnatal days (P) 1, 7, 14, and 21 using doublecortin (DCX...
Simon C Spanswick et al.
PloS one, 7(8), e43698-e43698 (2012-08-29)
Recent evidence suggests that the medial prefrontal cortex (MFC) is important for processing contextual information. Here we evaluate the performance of mice with MFC damage in a discrimination task that requires an association between an object and the context in...
Rui Ting Liu et al.
Behavioural brain research, 210(1), 24-31 (2010-02-02)
Considerable evidence has emerged supporting the neuroprotective and cognition-preserving effects of estrogen, but these benefits are complicated by the evidence that estrogen increases the risk of certain cancers. Selective estrogen receptor modulators (SERMs) that specifically target the brain while avoiding...
M R Williams et al.
European archives of psychiatry and clinical neuroscience, 263(1), 25-39 (2012-05-23)
Decreased cortical thickness and reduced activity as measured by fMRI in the grey matter of the subgenual cingulate cortex have been reported in schizophrenia and bipolar disorder, and cortical grey matter loss has been reliably reported in the frontal and...
William C Kwan et al.
The Journal of comparative neurology, 527(3), 558-576 (2018-01-03)
The primate visual brain possesses a myriad of pathways, whereby visual information originating at the retina is transmitted to multiple subcortical areas in parallel, before being relayed onto the visual cortex. The dominant retinogeniculostriate pathway has been an area of...
G Pavlíková et al.
International journal of oral and maxillofacial surgery, 40(8), 840-844 (2011-06-17)
Piezosurgery is a promising meticulous system for bone cutting, based on ultrasound microvibrations. It is thought that the impact of piezosurgery on the integrity of soft tissue is generally low, but it has not been examined critically. The authors undertook...
Maria Thom et al.
Epilepsy research, 102(1-2), 45-59 (2012-05-23)
Detailed neuropathological studies of the extent of hippocampal sclerosis (HS) in epilepsy along the longitudinal axis of the hippocampus are lacking. Neuroimaging studies of patients with temporal lobe epilepsy support that sclerosis is not always localised. The extent of HS...
Sachin Dev Verma et al.
Analytical chemistry, 84(16), 7218-7226 (2012-07-24)
The study of ligand interaction with G-quadruplex DNA is an active research area, because many ligands are shown to bind G-quadruplex structures, showing anticancer effects. Here, we show, for the first time, how fluorescence correlation spectroscopy (FCS) can be used...
Christos Zavos et al.
Ophthalmic research, 47(3), 150-156 (2011-11-19)
To investigate the role of Helicobacter pylori in primary open-angle glaucoma (POAG) pathophysiology by detecting its presence in eye biopsies of POAG patients during trabeculectomy. Fifty-one consecutive patients who underwent trabeculectomy for POAG not responsive to antiglaucoma therapy, and 35...
D Shukla et al.
The Journal of forensic odonto-stomatology, 30(1), 29-37 (2012-09-25)
Dental cementum is a specialized calcified structure covering the root of a tooth. This study aims to investigate cementum using various stains which can be exceedingly useful in investigation, observation and diagnosis. 4µm sections of 25 extracted normal teeth, 25...
P Perez-Mendes et al.
Epilepsy research, 96(1-2), 45-57 (2011-05-31)
Here we describe a new non-human primate model of temporal lobe epilepsy (TLE) to better investigate the cause/effect relationships of human TLE. Status epilepticus (SE) was induced in adult marmosets by pilocarpine injection (250mg/kg; i.p.). The animals were divided in...
G A Romanova et al.
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine, 45(3), 39-43 (2011-09-16)
Effects of 14-d suspension on the processes of rats' nervous cells conjugation in the brain cognitive cortex were studied. Signs of cognitive functions degradation and decrease of the number of conjugated nervous cells were found in the experimental group after...
Gobind Das et al.
The Analyst, 137(8), 1785-1792 (2012-02-23)
We propose a large-area SERS device with efficient fluorescence quenching capability. The substrate is based on anodic porous alumina templates with various pore size and wall thickness as small as 15 and 36 nm, respectively. The nano-patterned SERS substrate, with...
N Pamidi et al.
Bratislavske lekarske listy, 113(10), 583-588 (2012-10-26)
The present study was designed to evaluate the diabetes induced neuronal damage in the hippocampus of the rat brain. Diabetes mellitus is an endocrine metabolic disorder of impaired carbohydrate, fat and protein metabolisms characterized by chronic hyperglycemia. The neurological consequences...
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