Showing 1-20 of 20 results for "C5789"
Kunikazu Tsuji et al.
Cell transplantation, 26(6), 1089-1102 (2017-02-01)
Flow cytometric analysis of cell surface antigens is a powerful tool for the isolation and characterization of stem cells residing in adult tissues. In contrast to the collection of hematopoietic stem cells, the process of enzymatic digestion is usually necessary...
Rosa G M Lammerts et al.
Frontiers in immunology, 11, 1643-1643 (2020-08-28)
Introduction: Proteinuria contributes to progression of renal damage, partly by complement activation on proximal tubular epithelial cells. By pattern recognition, properdin has shown to bind to heparan sulfate proteoglycans on tubular epithelium and can initiate the alternative complement pathway (AP)....
Natalia Ronkina et al.
Journal of immunology (Baltimore, Md. : 1950), 203(8), 2291-2300 (2019-09-19)
Tristetraprolin (TTP) is an RNA-binding protein and an essential factor of posttranscriptional repression of cytokine biosynthesis in macrophages. Its activity is temporally inhibited by LPS-induced p38MAPK/MAPKAPK2/3-mediated phosphorylation, leading to a rapid increase in cytokine expression. We compared TTP expression and...
Liang Sun et al.
Biochimica et biophysica acta, 1854(5), 365-380 (2015-01-24)
The identification of the activator of heat shock protein 90 (Hsp90) ATPase's (Aha1) protein-protein interaction (PPI) network will provide critical insights into the relationship of Aha1 with multi-molecular complexes and shed light onto Aha1's interconnections with Hsp90-regulated biological functions. Flag-tagged...
S K Kavoussi et al.
Molecular human reproduction, 15(10), 687-692 (2009-08-01)
The aim of this study was to investigate whether peroxisome proliferator-activated receptor (PPAR)-gamma activation has an effect on the attachment of endometrial cells to peritoneal mesothelial cells in a well-established in vitro model of the early endometriotic lesion. The endometrial...
Vesna Nikolova-Krstevski et al.
BMC genomics, 9, 240-240 (2008-05-24)
Endothelial differentiation occurs during normal vascular development in the developing embryo. This process is recapitulated in the adult when endothelial progenitor cells are generated in the bone marrow and can contribute to vascular repair or angiogenesis at sites of vascular...
Impact of integrin-matrix matching and inhibition of apoptosis on the survival of purified human beta-cells in vitro
Ris F, et al.
Diabetologia, 45(6), 841-850 (2002)
Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells
Oak PS, et al.
International Journal of Cancer. Journal International Du Cancer, 131(12), 2808-2819 (2012)
Evidence for lipopolysaccharide induced differentiation of RAW264. 7 murine macrophage cell line into dendritic like cells
Saxena RK, et al.
Journal of Biosciences, 28(1), 129-134 (2003)
Philip Robinson et al.
PloS one, 6(6), e19802-e19802 (2011-06-23)
Voltage-gated calcium channels (Ca(v)) exist as heteromultimers comprising a pore-forming α(1) with accessory β and α(2)δ subunits which modify channel trafficking and function. We previously showed that α(2)δ-1 (and likely the other mammalian α(2)δ isoforms--α(2)δ-2, 3 and 4) is required...
Grégory Verdeil et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(43), 16683-16688 (2008-10-22)
Because of mechanisms of self-tolerance, many tumor-specific CD8 T cells exhibit low avidity for tumor antigens and would benefit from strategies that enhance their numbers and effector function. Here we demonstrate that the combined use of two different types of...
Comparison of enzymatic and non-enzymatic means of dissociating adherent monolayers of mesenchymal stem cells
Heng BC, et al.
Biological Procedures Online, 11(1), 161-161 (2009)
Umut Gazi et al.
The Journal of biological chemistry, 286(10), 7822-7829 (2011-01-06)
The mannose receptor (MR) is an endocytic type I membrane molecule with a broad ligand specificity that is involved in both hemostasis and pathogen recognition. Membrane-anchored MR is cleaved by a metalloproteinase into functional soluble MR (sMR) composed of the...
Maria Bogdanova et al.
Scientific reports, 9(1), 12934-12934 (2019-09-12)
Valve interstitial cells (VICs) are crucial in the development of calcific aortic valve disease. The purpose of the present investigation was to compare the phenotype, differentiation potential and stem cell-like properties of cells from calcified and healthy aortic valves. VICs...
Ji-Hee Kim et al.
Experimental & molecular medicine, 52(8), 1298-1309 (2020-08-10)
Endothelial progenitor cell (EPC) dysfunction impairs vascular function and remodeling in inflammation-associated diseases, including preeclampsia. However, the underlying mechanism of this inflammation-induced dysfunction remains unclear. In the present study, we found increases in TNF-α and miR-31/155 levels and reduced numbers...
Andrew M Edwards et al.
PloS one, 6(4), e18899-e18899 (2011-04-29)
Staphylococcus aureus is a commensal organism and a frequent cause of skin and soft tissue infections, which can progress to serious invasive disease. This bacterium uses its fibronectin binding proteins (FnBPs) to invade host cells and it has been hypothesised...
Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells.
Junttila TT, Li J, Johnston J, et al.
Cancer Research, 74(19), 5561-5571 (2014)
Giacomo Canesin et al.
Scientific reports, 10(1), 13958-13958 (2020-08-20)
Cancer stem cells (CSCs) are a small subpopulation of quiescent cells with the potential to differentiate into tumor cells. CSCs are involved in tumor initiation and progression and contribute to treatment failure through their intrinsic resistance to chemo- or radiotherapy...
Differential effects of RU486 reveal distinct mechanisms for glucocorticoid repression of prostaglandin E2 release
Chivers JE, et al.
European Journal of Biochemistry, 271(20), 4042-4052 (2004)
Richard Apps et al.
Immunology, 124(3), 322-328 (2008-01-22)
Human leucocyte antigen (HLA)-C is expressed at lower levels than other classical HLA-I molecules on somatic cells. Surface HLA-C proteins can occur as conventionally beta(2)-microglobulin (beta2m)-associated complexes or as open conformers dissociated from peptide and/or beta(2)m. We investigated the conformation...

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