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Anil K Philip et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 658-666 (2008-01-22)
In the present study, both disintegrating and non-disintegrating polymeric capsular system in achieving delayed as well as improved osmotic flow for the model drug cefadroxil was developed. Asymmetric membrane in membrane capsule (AMMC) was prepared on a glass mold pin
Detection limits of ?-lactam antibiotics in ewe milk by Penzym enzymatic test
Althaus.L.R, et al.
Journal of Food Protection, 64(11), 1844-1847 (2001)
Elham Shoghi et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(1-2), 291-300 (2012-11-28)
The solubility vs. pH profiles of five ionizable drugs of different nature (a monoprotic acid, a monoprotic base, a diprotic base and two amphoteric compounds showing a zwitterionic species each one) have been determined through two different methodologies: the classical
I Fujimori
The Japanese journal of antibiotics, 35(12), 2736-2747 (1982-12-01)
Mohamed A Kamal et al.
Drug metabolism and pharmacokinetics, 23(4), 236-242 (2008-09-03)
Pept2 knockout mice are an important tool to evaluate the evolving role and relevance of this proton-coupled oligopeptide transporter beyond drug disposition, where the transporter also modulates the pharmacodynamic and toxicodynamic effects of drug substrates. Our in vivo studies with
Mikihisa Takano et al.
Life sciences, 93(17), 630-636 (2013-08-31)
The purpose of this study was to clarify the expression and function of peptide transporter 2 (PEPT2) in primary cultured alveolar type II epithelial cells and in transdifferentiated type I-like cells. Real-time PCR analysis, uptake study of [(3)H]Gly-Sar, and immunostaining
[Multifocal osteoarticular infection caused by Staphylococcus aureus: when antibiotic resistance is not the problem].
Andrés Pérez et al.
Enfermedades infecciosas y microbiologia clinica, 26(9), 599-600 (2008-12-23)
DRESS syndrome from cefadroxil confirmed by positive patch test.
M Hernanto et al.
Allergy, 62(10), 1216-1217 (2007-06-21)
Najma Sultana et al.
Pakistan journal of pharmaceutical sciences, 20(4), 305-310 (2007-07-03)
Evidences supporting the introduction of metallic elements in several biological processes are rapidly accumulating. Likewise, many drugs possess modified toxicological and pharmacological properties when in the form of metal complexes. In order to ascertain the role of various essential and
Baboon syndrome.
Bhawana Dhingra et al.
Indian pediatrics, 44(12), 937-937 (2008-01-08)
Generalized pustulosis.
Sudip Kumar Ghosh et al.
Indian pediatrics, 45(11), 934-935 (2008-11-26)
Harry G Brittain
Journal of pharmaceutical sciences, 96(10), 2757-2764 (2007-07-11)
Although cefadroxil does not exhibit the phenomenon of photoluminescence when dissolved in a fluid medium, the compound has been found to exhibit fluorescence in its solid-state monohydrate crystal form. The monohydrate was found to exhibit complicated photoluminescence, where two different
Bei Yang et al.
Drug metabolism and disposition: the biological fate of chemicals, 41(3), 608-614 (2012-12-25)
The purpose of this study was to quantitatively determine the contribution of PepT1 [peptide transporter 1 (SLC15A1)] to the intestinal permeability of valacyclovir, an ester prodrug of the antiviral drug acyclovir. In situ single-pass intestinal perfusions were employed (pH 6.5
D S Bhalerao et al.
Indian journal of leprosy, 82(4), 205-207 (2011-03-26)
Female aged 55 years presented with signs and symptoms of borderline lepromatous leprosy and presence of a non-healing ulcer and multiple haemorrhagic blisters over dorsum of both feet. Discharge from the various lesions was subjected to microbiological examination and an
[Deep vein thrombosis and septic pulmonary emboli associated with acute paediatric osteomyelitis due to methicillin-sensitive Staphylococcus aureus producing Panton-Valentine leukocidin].
Ignacio Obando et al.
Enfermedades infecciosas y microbiologia clinica, 29(7), 550-551 (2011-04-19)
Sayed H Auda et al.
Electrophoresis, 30(6), 1066-1070 (2009-02-21)
The present study describes the application of CE to investigate the interaction between a cephalosporin, cefadroxil and different metal ions. This study aims at quantifying the interaction of cefadroxil with Zn(2+), Al(3+), Fe(3+), Cu(2+) and Co(2+) ions using the effective
Zhuming Wang et al.
Talanta, 83(2), 312-319 (2010-11-30)
The luminol-bovine serum albumin chemiluminescence system was proposed for the first time. It was found that the hydrophilic luminol bound to the hydrophilic domain at Trp(134) of BSA with accelerating the electrons transferring rate of excited 3-aminophthalate, which led to
B Tanrisever et al.
Drugs, 32 Suppl 3, 1-16 (1986-01-01)
Cefadroxil is an oral cephalosporin which is similar to cephalexin and cephradine in structure and spectrum of antibacterial activity, but has different pharmacokinetic properties. Not only does cefadroxil exhibit a longer serum half-life, and thus a prolonged duration of activity
Dirk R de Waart et al.
Drug metabolism and disposition: the biological fate of chemicals, 40(3), 515-521 (2011-12-15)
Some cephalosporins, such as cefadroxil, are orally available. H(+)-coupled peptide transporter 1 mediates the transport of cephalosporins across the apical membrane of enterocytes. It is not known which mechanism(s) is responsible for the subsequent transport of cephalosporins across the basolateral
Monica Sala-Rabanal et al.
American journal of physiology. Renal physiology, 294(6), F1422-F1432 (2008-03-28)
The human proton/oligopeptide cotransporters hPEPT1 and hPEPT2 have been targeted to enhance the bioavailability of drugs and prodrugs. Previously, we established the mechanisms of drug transport by hPEPT1. Here, we extend these studies to hPEPT2. Major variants hPEPT2*1 and hPEPT2*2
Eunice Kazue Kano et al.
Arzneimittel-Forschung, 58(1), 42-47 (2008-03-29)
Two different cefadroxil (CAS 50370-12-2) formulations were evaluated for their relative bioavailability in 24 healthy volunteers who received a single 500 mg oral dose of each preparation. An open, randomized clinical trial designed as a two-period crossover study with a
Maria M Posada et al.
Pharmaceutical research, 30(4), 1017-1025 (2012-12-12)
To determine the contribution of intestinal PepT1 on the permeability and oral absorption of the β-lactam antibiotic drug cefadroxil. The effective permeability (P eff ) of cefadroxil was evaluated in wild-type and PepT1 knockout mice following in situ single-pass intestinal
G Lamba et al.
The West Indian medical journal, 60(3), 346-348 (2012-01-10)
We report a life-threatening anaphylactic reaction to cefadroxil in a 60-year old female with no previous history of allergies to penicillins. Cefadroxil is a first-generation cephalosporin and anaphylactic reactions to it in patients with no previous history of penicillin allergy
Scleredema following scabies infestation.
Amit K Malhotra et al.
Pediatric dermatology, 25(1), 136-138 (2008-02-29)
Detection limits of antimicrobials in ewe milk by Delvotest photometric measurements
Althaus R, et al.
Journal of Dairy Science, 86(2), 457-463 (2003)
Robert Six et al.
Journal of the American Veterinary Medical Association, 233(3), 433-439 (2008-08-05)
To evaluate the efficacy and safety of administration of cefovecin, compared with cefadroxil, for treatment of naturally occurring secondary superficial pyoderma, abscesses, and infected wounds in dogs. Multicenter, randomized, positive-controlled clinical trial. 235 client-owned dogs. Dogs with clinical signs of
Liquid-chromatographic determination of five orally active cephalosporins--cefixime, cefaclor, cefadroxil, cephalexin, and cephradine--in human serum
McAteer.AJ, et al.
Clinical Chemistry, 33(10), 1788-1790 (1987)
David E Smith et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 31(1), 250-261 (2010-06-24)
The purpose of this study was to define the cerebrospinal fluid (CSF) clearance kinetics, choroid plexus uptake, and parenchymal penetration of PEPT2 substrates in different regions of the brain after intracerebroventricular administration. To accomplish these objectives, we performed biodistribution studies
Anil K Philip et al.
Pharmaceutical development and technology, 16(5), 457-465 (2010-05-21)
In the present study, an intestinal pH, disintegrating and non-disintegrating dual capsular system using formaldehyde vapor and phase transition technique, respectively, was developed to achieve delayed as well as improved osmotic flow for the model drug cefadroxil. Formaldehyde vapor was
Mounira Krifa et al.
Environmental science and pollution research international, 20(6), 3836-3842 (2012-11-28)
Among all the pharmaceutical drugs that contaminate the environment, antibiotics occupy an important place due to their high consumption rates in both veterinary and human medicine. The present study examined the ability of Pseudomonas putida to grow on the antibiotic
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