Showing 1-30 of 35 results for "C9080"
Cancer cell motility is affected through 3D cell culturing and SCF/c-Kit pathway but not by X-irradiation
Eberle F, et al.
Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology, 119(3) (2016)
Nidheesh Dadheech et al.
Stem cell research & therapy, 11(1), 327-327 (2020-08-01)
Despite the potential, bone marrow-derived mesenchymal stem cells (BMSCs) show limitations for beta (ß)-cell replacement therapy due to inefficient methods to deliver BMSCs into pancreatic lineage. In this study, we report TGF-ß family member protein, Activin-a potential to stimulate efficient...
HaYeun Ji et al.
Biomaterials, 85, 180-194 (2016-02-14)
Access to smooth muscle cells (SMC) would create opportunities for tissue engineering, drug testing, and disease modeling. Herein we report the direct conversion of human endothelial progenitor cells (EPC) to induced smooth muscle cells (iSMC) by induced expression of MYOCD....
Morphology of the myoepithelial cell: immunohistochemical characterization from resting to motile phase
Beha G, et al.
TheScientificWorldJournal, 2012 (2012)
Endometrial stromal and epithelial cells exhibit unique aberrant molecular defects in patients with endometriosis
Logan PC, et al.
Reproductive Sciences, 25(1) (2018)
Annette Schmidt et al.
Stem cells (Dayton, Ohio), 24(7), 1750-1758 (2006-07-11)
Little is known about the migration of mesenchymal stem cells (MSCs). Some therapeutic approaches had demonstrated that MSCs were able to regenerate injured tissues when applied from different sites of application. This implies that MSCs are not only able to...
Loraine L Y Chiu et al.
Tissue engineering. Part A, 17(11-12), 1465-1477 (2008-09-12)
The main objectives of current work were (1) to compare the effects of monophasic or biphasic electrical field stimulation on structure and function of engineered cardiac organoids based on enriched cardiomyocytes (CM) and (2) to determine if electrical field stimulation...
Intermediate filaments of the vimentin and prekeratin type in human epidermis
Mahrle G, et al.
The Journal of Investigative Dermatology, 81(1), 46-48 (1983)
Minhua H Wang et al.
Journal of neuroscience methods, 177(2), 403-419 (2008-12-06)
Direct protein transfection is a potentially valuable tool for studying protein function in basic and clinical research. A major challenge is to enable a sufficiently large amount of protein to penetrate the plasma membrane of the transfected cells. Pep-1, a...
Munehiro Yuhki et al.
Reproductive biology and endocrinology : RB&E, 9, 104-104 (2011-08-02)
Studies on the mechanisms of decidualization and endometriosis are often hampered by lack of primary endometrial cells. To facilitate in vitro studies, we established a human endometrial stromal cell line, KC02-44D, immortalized with human telomerase reverse transcriptase. Upon exposure to...
Basic fibroblast growth factor controls migration in human mesenchymal stem cells
Schmidt A, et al.
Stem Cells, 24(7), 1750-1758 (2006)
Nicolas Christoforou et al.
Scientific reports, 7, 40285-40285 (2017-01-11)
Transdifferentiation has been described as a novel method for converting human fibroblasts into induced cardiomyocyte-like cells. Such an approach can produce differentiated cells to study physiology or pathophysiology, examine drug interactions or toxicities, and engineer cardiac tissues. Here we describe...
Tanja Piatkowski et al.
Stem cells and development, 22(13), 1921-1931 (2013-02-13)
Adult newts efficiently regenerate the heart after injury in a process that involves proliferation of cardiac muscle and nonmuscle cells and repatterning of the myocardium. To analyze the processes that underlie heart regeneration in newts, we characterized the structural changes...
Michaela Graf et al.
Human reproduction (Oxford, England), 26(1), 59-66 (2010-11-30)
Dysfunction of cellular processes in the testes can lead to infertility, tumourigenesis or other testicular disorders. 14-3-3 proteins are known to play pivotal roles in cellular communication, signal transduction, intracellular trafficking, cell-cycle control, transcription and cytoskeletal structure and have been...
Ze-Wei Tao et al.
ASAIO journal (American Society for Artificial Internal Organs : 1992), 64(5), e105-e114 (2018-03-15)
Bioengineering cardiac tissue constructs with adult cardiomyocytes may help treat adult heart defects and injury. In this study, we fabricated cardiac tissue constructs by seeding adult rat cardiomyocytes on a fibrin gel matrix and analyzed the electromechanical properties of the...
Qianyi Luo et al.
Investigative ophthalmology & visual science, 60(6), 1928-1936 (2019-05-03)
Diabetes leads to the downregulation of the retinal Kir4.1 channels and Müller cell dysfunction. The insulin receptor substrate-1 (IRS-1) is a critical regulator of insulin signaling in Müller cells. Circadian rhythms play an integral role in normal physiology; however, diabetes...
Guangheng Li et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 20(9), 1611-1623 (2005-08-02)
After intramuscular implantation, BMP4-expressing NIH/3T3 fibroblasts and BMP4-expressing C2C12 myoblasts can promote ectopic cartilage and bone formation. Fibroblasts tend to undergo chondrogenesis, whereas myoblasts primarily undergo osteogenesis. These results suggest that endochondral bone formation may involve different cell types, a...
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Jule K Michler et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 93(1), 104-114 (2017-09-03)
The easily accessible niche represented by skin and its appendages may serve as a promising source to complement modern regenerative medicine for horses. In humans and in animal models for human medicine, the hair follicle and its stem cell niches...
Celimene Galiger et al.
Journal of cellular and molecular medicine, 18(7), 1321-1333 (2014-06-04)
Octamer binding trascription factor 4 (Oct4) is a transcription factor of POU family specifically expressed in embryonic stem cells (ESCs). A role for maintaining pluripotency and self-renewal of ESCs is assigned to Oct4 as a pluripotency marker. Oct4 can also...
Weiyong Shen et al.
Journal of neuroscience research, 88(7), 1485-1499 (2009-12-24)
Glial dysfunction is found in a number of retinal vascular diseases but its link with blood-retinal barrier (BRB) breakdown remains poorly understood. The present study tested the hypothesis that glial dysfunction is a major contributor to the BRB breakdown that...
Coexpression of keratin-and vimentin-type intermediate filaments in human metastatic carcinoma cells
Ramaekers FC, et al.
Proceedings of the National Academy of Sciences of the USA, 80(9), 2618-2622 (1983)
Arun Satelli et al.
Cellular and molecular life sciences : CMLS, 68(18), 3033-3046 (2011-06-04)
Vimentin, a major constituent of the intermediate filament family of proteins, is ubiquitously expressed in normal mesenchymal cells and is known to maintain cellular integrity and provide resistance against stress. Vimentin is overexpressed in various epithelial cancers, including prostate cancer...
Prakash Chelladurai et al.
Scientific reports, 10(1), 12864-12864 (2020-08-01)
Pharmacological modulation of class I histone deacetylases (HDAC) has been evaluated as a therapeutic strategy for pulmonary hypertension (PH) in experimental models of PH. However, information of their expression, regulation and transcriptional targets in human PH and the therapeutic potential...
Evaluation of nonperfused retinal vessels in ischemic retinopathy
Powner MB, et al.
Investigative Ophthalmology & Visual Science, 57(11) (2016)
Michael B Powner et al.
Ophthalmology, 117(12), 2407-2416 (2010-08-04)
To assess the histopathologic changes in a postmortem sample derived from an eye donor with macular telangiectasia (MacTel) type 2 to gain further insight into the cause of the disease. Clinicopathological case report. Postmortem tissue was collected from 5 different...
Engineering microenvironment for human cardiac tissue assembly in heart-on-a-chip platform.
Zhao, et al.
Matrix Biology, 189-204 (2021)
Jose Oca-Cossio et al.
Genetics, 165(2), 707-720 (2003-10-24)
The possibility of expressing mitochondrial DNA-coded genes in the nuclear-cytoplasmic compartment provides an attractive system for genetic treatment of mitochondrial disorders associated with mitochondrial DNA mutations. In theory, by recoding mitochondrial genes to adapt them to the universal genetic code...
Izabela Nita et al.
Scientific reports, 7, 41901-41901 (2017-02-06)
Idiopathic Pulmonary Fibrosis (IPF) is a progressive, irreversible lung disease with complex pathophysiology. Evidence of endoplasmic reticulum (ER) stress has been reported in alveolar epithelial cells (AEC) in IPF patients. Secreted mediators from bone marrow stem cells (BMSC-cm) have regenerative...
Weiyong Shen et al.
PloS one, 9(8), e104759-e104759 (2014-08-15)
Royal College of Surgeons (RCS) rats develop vasculopathy as photoreceptors degenerate. The aim of this study was to examine the effect of erythropoietin (EPO) on retinopathy in RCS rats. Fluorescein angiography was used to monitor retinal vascular changes over time....

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