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Organism
Showing 1-30 of 123 results for "cell_division"
BOD1
biorientation of chromosomes in cell division 1
Synonyms:
FAM44B
Species:
Human BOD1 (91272), Mouse Bod1 (69556), Rat Bod1 (287173), Zebrafish bod1 (767743), chicken BOD1 (416210), domestic cat BOD1 (101092914), cow BOD1 (540063), dog BOD1 (612987), sheep BOD1 (101107045), domestic guinea pig Bod1 (100727784), naked mole-rat Bod1 (101723040)
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CDCA5
cell division cycle associated 5
Synonyms:
SORORIN
Species:
Human CDCA5 (113130), Mouse Cdca5 (67849), Rat Cdca5 (684771), naked mole-rat Cdca5 (101701382), domestic guinea pig Cdca5 (100724921), Zebrafish cdca5 (559398), domestic cat CDCA5 (101083033), cow CDCA5 (613318), dog CDCA5 (612071)
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CDCA3
cell division cycle associated 3
Synonyms:
GRCC8, TOME-1
Species:
Human CDCA3 (83461), Mouse Cdca3 (14793), Rat Cdca3 (297594), naked mole-rat Cdca3 (101719596), domestic guinea pig Cdca3 (100725438), sheep CDCA3 (101110222), chicken CDCA3 (770517), dog CDCA3 (611617), cow CDCA3 (614434), domestic cat CDCA3 (101085049)
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CDCA4
cell division cycle associated 4
Synonyms:
HEPP, SEI-3/HEPP
Species:
Human CDCA4 (55038), Mouse Cdca4 (71963), Rat Cdca4 (500727), chicken CDCA4 (423500), cow CDCA4 (527837), domestic cat CDCA4 (101100819), dog CDCA4 (612703), sheep CDCA4 (101105444), domestic guinea pig Cdca4 (100715479), naked mole-rat Cdca4 (101697404)
Summary:
This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulaton of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, Sep 2008
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CDCA8
cell division cycle associated 8
Synonyms:
BOR, BOREALIN, DasraB, MESRGP
Species:
Human CDCA8 (55143), Mouse Cdca8 (52276), Rat Cdca8 (500545), domestic guinea pig Cdca8 (100723828), naked mole-rat Cdca8 (101700921), sheep CDCA8 (101115324), Zebrafish cdca8 (492815), cow CDCA8 (508022), domestic cat CDCA8 (101091294), dog CDCA8 (608164), chicken CDCA8 (425084), chicken CDCA8 (777014)
Summary:
This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16. [provided by RefSeq, Apr 2013
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CDCA2
cell division cycle associated 2
Synonyms:
Repo-Man
Species:
Human CDCA2 (157313), Mouse Cdca2 (108912), Rat Cdca2 (305984), chicken CDCA2 (419524), cow CDCA2 (515287), Horse CDCA2 (100059371), domestic cat CDCA2 (101081798), dog CDCA2 (477377), sheep CDCA2 (101111159), domestic guinea pig Cdca2 (100733006), naked mole-rat Cdca2 (101706363)
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CDC20
cell division cycle 20
Synonyms:
CDC20A, bA276H19.3, p55CDC
Species:
Human CDC20 (991), Mouse Cdc20 (107995), Rat Cdc20 (64515), Zebrafish cdc20 (406353), cow CDC20 (281675), cow CDC20 (515376), Horse CDC20 (100053348), domestic cat CDC20 (101097259), dog CDC20 (482534), chicken CDC20 (424563), naked mole-rat Cdc20 (101707229), domestic guinea pig Cdc20 (100718545), sheep CDC20 (101110548)
Summary:
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008
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CDC26
cell division cycle 26
Synonyms:
ANAPC12, APC12, C9orf17
Species:
Human CDC26 (246184), Mouse Cdc26 (66440), Rat Cdc26 (366381), Zebrafish cdc26 (445501), cow CDC26 (777693), domestic cat CDC26 (101095692), dog CDC26 (481679), chicken CDC26 (417269), naked mole-rat Cdc26 (101705159), domestic guinea pig Cdc26 (100732729), sheep CDC26 (101108105)
Summary:
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex (APC). APC is composed of a group of highly conserved proteins and functions as a cell cycle-regulated ubiquitin-protein ligase. APC thus is responsible for the cell cycle regulated proteolysis of various proteins. [provided by RefSeq, Jul 2008
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CDC40
cell division cycle 40
Synonyms:
EHB3, PRP17, PRPF17
Species:
Human CDC40 (51362), Mouse Cdc40 (71713), Rat Cdc40 (361859), Zebrafish cdc40 (494534), cow CDC40 (514003), domestic cat CDC40 (101080793), dog CDC40 (475025), chicken CDC40 (421760), naked mole-rat Cdc40 (101706880), domestic guinea pig Cdc40 (100716434), sheep CDC40 (101112230)
Summary:
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008
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CDCA7
cell division cycle associated 7
Synonyms:
JPO1
Species:
Human CDCA7 (83879), Mouse Cdca7 (66953), Rat Cdca7 (311742), chicken CDCA7 (425630), cow CDCA7 (614893), Horse CDCA7 (100064197), domestic cat CDCA7 (101094441), dog CDCA7 (488403), chicken CDCA7 (776142), domestic guinea pig Cdca7 (100730407), naked mole-rat Cdca7 (101708827), sheep CDCA7 (101111162)
Summary:
This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008
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CDC123
cell division cycle 123
Synonyms:
C10orf7, D123
Species:
Human CDC123 (8872), Mouse Cdc123 (98828), Rat Cdc123 (116656), Zebrafish cdc123 (393694), cow CDC123 (514926), Horse CDC123 (100056777), domestic cat CDC123 (101084888), dog CDC123 (478005), chicken CDC123 (426366), naked mole-rat Cdc123 (101724853), domestic guinea pig Cdc123 (100723172), sheep CDC123 (101117525)
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CDC45
cell division cycle 45
Synonyms:
CDC45L, CDC45L2, PORC-PI-1
Species:
Human CDC45 (8318), Mouse Cdc45 (12544), Rat Cdc45 (287961), Zebrafish cdc45 (406695), cow CDC45 (507122), chicken CDC45 (416776), dog CDC45 (486421), Horse CDC45 (100050871), domestic cat CDC45 (101097519), Thale Cress CDC45 (822101), naked mole-rat Cdc45 (101714952), domestic guinea pig Cdc45 (100728375), sheep CDC45 (101121376)
Summary:
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013
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CDCA7L
cell division cycle associated 7-like
Synonyms:
JPO2, R1, RAM2
Species:
Human CDCA7L (55536), Mouse Cdca7l (217946), Rat Cdca7l (619566), chicken CDCA7L (420608), domestic cat CDCA7L (101095241), cow CDCA7L (514631), Horse CDCA7L (100067524), dog CDCA7L (482347), sheep CDCA7L (101108042), naked mole-rat Cdca7l (101701569), domestic guinea pig Cdca7l (100733412)
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CDC27
cell division cycle 27
Synonyms:
ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2
Species:
Human CDC27 (996), Mouse Cdc27 (217232), Rat Cdc27 (360643), Zebrafish cdc27 (30450), cow CDC27 (540660), Horse CDC27 (100054552), chicken CDC27 (419960), domestic cat CDC27 (101091234), dog CDC27 (490924), fruit fly Cdc27 (38798), sheep CDC27 (101121276), domestic guinea pig Cdc27 (100731091), naked mole-rat Cdc27 (101717421)
Summary:
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008
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CDC34
cell division cycle 34
Synonyms:
E2-CDC34, UBC3, UBCH3, UBE2R1
Species:
Human CDC34 (997), Mouse Cdc34 (216150), Rat Cdc34 (299602), chicken CDC34 (425483), dog CDC34 (476759), domestic cat CDC34 (101090492), cow CDC34 (616156), naked mole-rat Cdc34 (101722410), domestic guinea pig Cdc34 (100723029), sheep CDC34 (101107962), Domestic Rabbit CDC34 (100009436)
Summary:
The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. [provided by RefSeq, Jul 2008
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CDC7
cell division cycle 7
Synonyms:
CDC7L1, HsCDC7, Hsk1, huCDC7
Species:
Human CDC7 (8317), Mouse Cdc7 (12545), Rat Cdc7 (360908), Zebrafish cdc7 (492768), cow CDC7 (516094), Horse CDC7 (100060468), domestic cat CDC7 (101085227), dog CDC7 (479955), chicken CDC7 (424507), sheep CDC7 (101102190), domestic guinea pig Cdc7 (100716321), naked mole-rat Cdc7 (101720948)
Summary:
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008
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CDC25A
cell division cycle 25A
Synonyms:
CDC25A2
Species:
Human CDC25A (993), Mouse Cdc25a (12530), Rat Cdc25a (171102), chicken CDC25A (420375), cow CDC25A (520188), Horse CDC25A (100064223), domestic cat CDC25A (101098445), dog CDC25A (484780), sheep CDC25A (101113178), domestic guinea pig Cdc25a (100721008), naked mole-rat Cdc25a (101699133)
Summary:
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008
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CCAR1
cell division cycle and apoptosis regulator 1
Synonyms:
RP11-437A18.1
Species:
Human CCAR1 (55749), Mouse Ccar1 (67500), Rat Ccar1 (361849), Zebrafish ccar1 (337744), cow CCAR1 (767587), Horse CCAR1 (100063156), domestic cat CCAR1 (101091814), dog CCAR1 (479230), chicken CCAR1 (423692), naked mole-rat Ccar1 (101703576), domestic guinea pig Ccar1 (100719892), sheep CCAR1 (101106390)
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CDC6
cell division cycle 6
Synonyms:
CDC18L, HsCDC18, HsCDC6
Species:
Human CDC6 (990), Mouse Cdc6 (23834), Rat Cdc6 (360621), naked mole-rat Cdc6 (101724964), domestic guinea pig Cdc6 (100729621), sheep CDC6 (101107536), Domestic Rabbit CDC6 (100357421), Zebrafish cdc6 (402825), Thale Cress CDC6 (817518), dog CDC6 (480527), cow CDC6 (515301), Horse CDC6 (100067788), domestic cat CDC6 (101082791), fruit fly Cdc6 (38989)
Summary:
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008
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CDC23
cell division cycle 23
Synonyms:
ANAPC8, APC8, CUT23
Species:
Human CDC23 (8697), Mouse Cdc23 (52563), Rat Cdc23 (291689), Zebrafish cdc23 (393907), cow CDC23 (512651), domestic cat CDC23 (101086445), dog CDC23 (481526), chicken CDC23 (771857), fruit fly cdc23 (35315), naked mole-rat Cdc23 (101711746), domestic guinea pig Cdc23 (100733068), sheep CDC23 (101109612), Domestic Rabbit CDC23 (100345665)
Summary:
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008
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CDC37
cell division cycle 37
Synonyms:
P50CDC37
Species:
Human CDC37 (11140), Mouse Cdc37 (12539), Rat Cdc37 (114562), Zebrafish cdc37 (394013), cow CDC37 (520883), domestic cat CDC37 (101090419), dog CDC37 (484955), chicken CDC37 (395430), fruit fly Cdc37 (38232), naked mole-rat Cdc37 (101716587), domestic guinea pig Cdc37 (100716016), sheep CDC37 (101113585)
Summary:
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008
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CDC16
cell division cycle 16
Synonyms:
ANAPC6, APC6, CUT9
Species:
Human CDC16 (8881), Mouse Cdc16 (69957), Rat Cdc16 (290875), Zebrafish cdc16 (562014), cow CDC16 (614342), Horse CDC16 (100069285), domestic cat CDC16 (101092821), dog CDC16 (607100), fruit fly cdc16 (42753), chicken CDC16 (418735), sheep CDC16 (101117773), Domestic Rabbit CDC16 (100359101), domestic guinea pig Cdc16 (100725418), naked mole-rat Cdc16 (101724017)
Summary:
This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein interaction. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008
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CDC20B
cell division cycle 20B
Species:
Human CDC20B (166979), Mouse Cdc20b (238896), chicken CDC20B (426169), domestic cat CDC20B (101095396), cow CDC20B (522049), Horse CDC20B (100062460), dog CDC20B (478058), sheep CDC20B (101116347), domestic guinea pig Cdc20b (100726479), naked mole-rat Cdc20b (101706366)
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CDC14A
cell division cycle 14A
Synonyms:
cdc14, hCDC14
Species:
Human CDC14A (8556), Mouse Cdc14a (229776), Rat Cdc14a (310806), chicken CDC14A (424466), dog CDC14A (479926), domestic cat CDC14A (101088601), cow CDC14A (614777), Horse CDC14A (100055766), sheep CDC14A (101121483), Domestic Rabbit CDC14A (100346294), domestic guinea pig Cdc14a (100722401), naked mole-rat Cdc14a (101724071)
Summary:
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008
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CDC25B
cell division cycle 25B
Species:
Human CDC25B (994), Mouse Cdc25b (12531), Rat Cdc25b (171103), naked mole-rat Cdc25b (101701077), domestic guinea pig Cdc25b (100716851), sheep CDC25B (101120511), domestic cat CDC25B (101092757), cow CDC25B (505847), Horse CDC25B (100052425), dog CDC25B (485790)
Summary:
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008
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Species:
Mouse Bod1l (665775), chicken BOD1L (422838), cow BOD1L (508527), dog BOD1L (479089)
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CDC25C
cell division cycle 25C
Synonyms:
CDC25, PPP1R60
Species:
Human CDC25C (995), Mouse Cdc25c (12532), Rat Cdc25c (307511), dog CDC25C (610456), cow CDC25C (507731), Horse CDC25C (100062352), domestic cat CDC25C (101086942), sheep CDC25C (101110327), Domestic Rabbit CDC25C (100343637), naked mole-rat Cdc25c (101712931)
Summary:
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008
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BOD1L1
biorientation of chromosomes in cell division 1-like 1
Synonyms:
BOD1L, FAM44A
Species:
Human BOD1L1 (259282), Rat Bod1l1 (207118), domestic cat BOD1L1 (101092265), naked mole-rat Bod1l1 (101725647), domestic guinea pig Bod1l1 (100730155), sheep BOD1L1 (101115795)
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CDC42
cell division cycle 42
Synonyms:
CDC42Hs, G25K
Species:
Human CDC42 (998), Mouse Cdc42 (12540), Rat Cdc42 (64465), sheep CDC42 (101102792), domestic guinea pig Cdc42 (100717195), naked mole-rat Cdc42 (101701374), Zebrafish cdc42 (336839), fruit fly Cdc42 (32981), cow CDC42 (532712), domestic cat CDC42 (101094772), dog CDC42 (403934), chicken CDC42 (395917)
Summary:
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013
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CDC14B
cell division cycle 14B
Synonyms:
CDC14B3, Cdc14B1, Cdc14B2, hCDC14B
Species:
Human CDC14B (8555), Mouse Cdc14b (218294), Rat Cdc14b (361195), Zebrafish cdc14b (393148), cow CDC14B (520428), Horse CDC14B (100062379), domestic cat CDC14B (101086096), dog CDC14B (476294), chicken CDC14B (427473), naked mole-rat Cdc14b (101713083), domestic guinea pig Cdc14b (100727486), sheep CDC14B (101110906)
Summary:
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008
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