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T Maślanka et al.
Polish journal of veterinary sciences, 16(2), 219-222 (2013-08-27)
Recently, we found that dexamethasone caused a depletion of CD25- CD4+ T cells, but it increased the number of CD25highCD4+ and CD25lowCD4+ T cells. We also determined meloxicam-induced increase in the number of CD25highCD4+ T cells. In view of this
N H Waldron et al.
British journal of anaesthesia, 110(2), 191-200 (2012-12-12)
The analgesic efficacy and adverse effects of a single perioperative dose of dexamethasone are unclear. We performed a systematic review to evaluate the impact of a single i.v. dose of dexamethasone on postoperative pain and explore adverse events associated with
D Rendina et al.
Minerva endocrinologica, 38(2), 211-215 (2013-06-05)
Multiple symmetric lipomatosis (MSL, OMIM 151800), is a rare disease characterised by the growth of uncapsulated masses of abnormal adipose tissue around the neck, shoulders or other parts of the trunk and typically associated with high ethanol intake. We describe
Aprepitant versus dexamethasone to prevent delayed emesis after chemotherapy.
Terry L Ng et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(20), 2184-2185 (2014-06-11)
Pierfrancesco Mirabelli et al.
Experimental eye research, 125, 118-127 (2014-06-17)
Inflammatory angiogenesis is the pathogenic mechanism of various sight-threatening eye diseases, among them corneal neovascularization. Current treatment options include steroids which have undesirable side effects, or anti-VEGF which has only limited efficacy. In an inflammatory environment, however, angiogenesis can be
Sa Luo et al.
Toxicology letters, 229(1), 85-92 (2014-06-10)
Various therapeutic regimes have been proposed with limited success for treatment of phosgene-induced acute lung injury (P-ALI). Corticoids were shown to be efficacious against chlorine-induced lung injury but there is still controversy whether this applies also to P-ALI. This study
Sapna Oberoi et al.
Pediatric blood & cancer, 61(12), 2218-2222 (2014-09-02)
Medication errors occur universally. Inappropriate administration of chemotherapy drugs can have adverse effects in cancer patients. Our objective was to assess the rate and type of medication errors in children with acute lymphoblastic leukemia (ALL) receiving oral chemotherapy in outpatient
Clinically relevant genetic advances in endocrinology.
Angela Rogers et al.
Clinical medicine (London, England), 13(3), 299-305 (2013-06-14)
Chao H Yang et al.
JAMA dermatology, 150(4), 426-428 (2014-02-21)
Cryoglobulins are cold-precipitating immunoglobulins that occur secondary to lymphoproliferative disorders, chronic viral infections, and autoimmune disorders. The treatment of cryoglobulinemia should target the underlying disorder; however, such an approach may be difficult, and therapeutic options remain limited for type I
Anja Baumann et al.
Molecular immunology, 64(1), 76-81 (2014-12-04)
Symptoms of allergic attacks frequently exhibit diurnal variations. Accordingly, we could recently demonstrate that mast cells and eosinophils - known as major effector cells of allergic diseases - showed an intact circadian clock. Here, we analyzed the role of the
Andrew Neill et al.
Emergency medicine journal : EMJ, 30(2), 165-166 (2013-01-26)
A short-cut review was carried out to establish whether the administration of dexamethasone reduced the risk of recurrence of migraine headaches at 24 h. Three hundred and fifteen articles were found using the reported search including two systematic reviews and
Eva Hoster et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(13), 1338-1346 (2014-04-02)
Mantle-cell lymphoma (MCL) is a distinct B-cell lymphoma associated with poor outcome. In 2008, the MCL International Prognostic Index (MIPI) was developed as the first prognostic stratification tool specifically directed to patients with MCL. External validation was planned to be
Louise Grahnemo et al.
The Journal of endocrinology, 224(1), 97-108 (2014-11-02)
Treatment with anti-inflammatory glucocorticoids is associated with osteoporosis. Many of the treated patients are postmenopausal women, who even without treatment have an increased risk of osteoporosis. Lymphocytes have been shown to play a role in postmenopausal and arthritis-induced osteoporosis, and
Jennifer E Flower et al.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 44(4), 1115-1119 (2014-01-24)
A 10-yr-old female spayed mixed breed tiger presented for a 9-day history of acute and nonprogressive paralysis of the pelvic limbs. Magnetic resonance imaging revealed a lesion suggestive of fibrocartilaginous embolic myelopathy with regional spinal cord edema, decreased disk signal
Theodore T Foley et al.
Plastic and reconstructive surgery, 133(5), 638e-644e (2014-04-30)
Dexamethasone, a common therapy for reducing hypertrophic scar, sometimes fails. However, in cell culture, all dexamethasone-treated fibroblasts die. In co-cultures, gap junction intercellular communications between mast cells and fibroblasts promote profibrotic activities. Does the co-culture of mast cells with fibroblasts
Joe Walter Kutz et al.
Expert opinion on pharmacotherapy, 14(17), 2399-2405 (2013-10-08)
Ciprofloxacin 0.3% with dexamethasone 0.1% (ciprofloxacin/dexamethasone) is an ototopical preparation for acute otitis externa, otorrhea with tympanostomy tubes, and is frequently used to treat chronic suppurative otitis media (CSOM). The advantage of topical therapy is the ability to deliver higher
David S Boyer et al.
Ophthalmology, 121(10), 1904-1914 (2014-06-08)
To evaluate the safety and efficacy of dexamethasone intravitreal implant (Ozurdex, DEX implant) 0.7 and 0.35 mg in the treatment of patients with diabetic macular edema (DME). Two randomized, multicenter, masked, sham-controlled, phase III clinical trials with identical protocols were
Wanderley Marques Bernardo et al.
Revista da Associacao Medica Brasileira (1992), 59(4), 387-391 (2013-07-23)
To verify the efficacy of dexamethasone in the prophylaxis of nausea and vomiting in patients submitted to laparoscopic cholecystectomy. This was a systematic review of the literature through the MEDLINE, Embase, and LILACS databases. Only controlled and randomized clinical trials
Aprepitant versus dexamethasone for delayed emesis: what is the role of the 5-hydroxytryptamine type 3 receptor antagonist palonosetron?
Luigi Celio et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(20), 2185-2186 (2014-06-11)
Kasima Ekthuwapranee et al.
The Journal of steroid biochemistry and molecular biology, 145, 38-48 (2014-10-12)
Glucocorticoids, hormones that are released in response to stress, induce neuronal cell damage. The hippocampus is a primary target of glucocorticoids in the brain, the effects of which include the suppression of cell proliferation and diminished neurogenesis in the dentate
Hyperkalemia: a clue to the diagnosis of adrenal insufficiency.
Daniel El Fassi et al.
Circulation, 128(24), 2620-2621 (2013-12-18)
Alice Pham et al.
Obstetrics and gynecology, 120(6), 1451-1458 (2012-11-22)
To estimate the beneficial and harmful effects of dexamethasone for prevention of postoperative nausea and vomiting in women undergoing laparoscopic gynecologic surgery. We searched the following bibliographic databases: MEDLINE (from 1946 to January 2012), Embase (from 1980 to 2012 week
Perineural dexamethasone and multimodal perineural analgesia: how much is too much?
Brian A Williams et al.
Anesthesia and analgesia, 118(5), 912-914 (2014-05-02)
Bahman Naghipour et al.
Middle East journal of anaesthesiology, 22(1), 53-57 (2013-07-10)
Different additives have been used to prolong regional blockade. We designed a prospective, randomized, double-blind, controlled clinical trial to evaluate the effect of dexamethasone added to bupivacaine-fentanyl on the duration of postoperative analgesia via epidural catheterization. Seventy two adult patients
A Oestmann et al.
Deutsche medizinische Wochenschrift (1946), 139(30), 1518-1520 (2014-07-30)
A 54-year old man had suffered from advanced multiple myeloma for two years. After initially good response the myeloma was refractrory to treatment with dexamethasone, cyclophosphamide, bortezomibe, zoledronate and additionally doxorubicine. The patient then complained of dyspnea without clinical signs
Perineural vs intravenous administration of dexamethasone: more data are available.
E Albrecht et al.
British journal of anaesthesia, 114(1), 160-160 (2014-12-17)
Chenming Yang et al.
Journal of biomedical nanotechnology, 9(9), 1617-1623 (2013-08-29)
The purpose of this research was to investigate the possibility of dexamethasone (DEX)-loaded PLGA-TPGS nanoparticles (NPs) in rabbits after intravitreal administration for the treatment of posterior segment diseases. The DEX-loaded PLGA-TPGS NPs were fabricated and characterized in terms of surface
Current treatment for multiple myeloma.
David Avigan et al.
The New England journal of medicine, 371(10), 961-962 (2014-09-04)
Chengyun Wang et al.
Experimental eye research, 129, 74-82 (2014-12-03)
Dexamethasone is a glucocorticoid that is widely used in the ophthalmic arena. The recent FDA approved dexamethasone implant can provide a three month efficacy but with high rate of drug related cataract and high intraocular pressure (IOP). It seems that
Shirzad Nasiri et al.
The American surgeon, 79(12), 1258-1262 (2013-12-20)
Voice alteration is one of the most common complications after thyroidectomy. It has a serious effect on social communication and economic and psychosocial status of patients. It has been hypothesized that inflammation and edema in the surgery site has a
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