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The prevalence of comorbidities in COPD patients, and their impact on health status and COPD symptoms in primary care patients: a protocol for an UNLOCK study from the IPCRG.
Björn Ställberg et al.
NPJ primary care respiratory medicine, 26, 16069-16069 (2016-11-18)
Ahmed Bassiouni et al.
Frontiers in cellular and infection microbiology, 10, 137-137 (2020-04-24)
This study offers a novel description of the sinonasal microbiome, through an unsupervised machine learning approach combining dimensionality reduction and clustering. We apply our method to the International Sinonasal Microbiome Study (ISMS) dataset of 410 sinus swab samples. We propose...
Simon Blank et al.
Human vaccines & immunotherapeutics, 13(10), 2482-2489 (2017-05-12)
Allergen-specific immunotherapy is the only curative treatment of honeybee venom (HBV) allergy, which is able to protect against further anaphylactic sting reactions. Recent analyses on a molecular level have demonstrated that HBV represents a complex allergen source that contains more...
Annice Heratizadeh et al.
The Journal of allergy and clinical immunology, 140(3), 845-853 (2017-03-01)
Atopic dermatitis (AD) is a chronic relapsing skin disease prevalent in 1% to 3% of adults in Western industrialized countries. We sought to investigate the effectiveness of educational training in an outpatient setting on coping with the disease, quality of...
New thioester substrates for fibrinoligase (coagulation factor XIIIa) and for transglutaminase. Transfer of the fluorescently labeled acyl group to amines and alcohols
Parameswaran KN
BioChemistry: An Indian Journal, 20(13), 3703-3711 (1981)
Lars Stryhn Bjerregaard et al.
BMC anesthesiology, 15, 91-91 (2015-06-13)
Despite extensive research, the debate continues as to the optimal way of guiding intraoperative and postoperative fluid therapy. In 2009 we changed our institutional guideline for perioperative fluid therapy in patients undergoing extrapleural pneumonectomy (EPP) and implemented the use of...
Désirée E S Larenas-Linnemann et al.
Current allergy and asthma reports, 18(5), 33-33 (2018-05-11)
Since omalizumab has been approved for urticaria, numerous randomized and real-life observational trials have been published. We reviewed the period January 2017-February 2018. Omalizumab is effective for the control of urticaria recalcitrant to antihistamines in different populations globally. The ratio...
He Na et al.
Archives of microbiology, 201(6), 807-816 (2019-03-16)
Rice blast, caused by Magnaporthe oryzae, is a serious threat to global rice production. In recent years, many pathogenicity genes of M. oryzae have been identified, although most of their functions remain unknown. In this study, we report the synergistic...
Thomas B Casale et al.
The journal of allergy and clinical immunology. In practice, 6(3), 923-935 (2017-11-28)
Adding tiotropium to existing inhaled corticosteroid (ICS) maintenance therapy with or without a long-acting β2-agonist (LABA) has been shown to be beneficial in patients with symptomatic asthma. To assess whether responses to tiotropium Respimat add-on therapy were influenced by patients'...
Alexander Egeberg et al.
The Journal of investigative dermatology, 139(2), 316-323 (2018-08-22)
In psoriasis patients, incidence rates of Crohn disease (CD) and ulcerative colitis (UC) have been increased in epidemiological studies and certain clinical trials, yet the association remains poorly understood. We studied a 20-year nationwide cohort of 235,038 Danish adults with...
A Valero et al.
Journal of investigational allergology & clinical immunology, 28(2), 67-90 (2018-01-19)
Nasal obstruction (NO) is defined as the subjective perception of discomfort or difficulty in the passage of air through the nostrils. It is a common reason for consultation in primary and specialized care and may affect up to 30%-40% of...
Geng Dou et al.
Science advances, 6(30), eaba2987-eaba2987 (2020-08-25)
Engineered extracellular vesicles (EVs) carrying therapeutic molecules are promising candidates for disease therapies. Yet, engineering EVs with optimal functions is a challenge that requires careful selection of functionally specific vesicles and a proper engineering strategy. Here, we constructed chimeric apoptotic...
Mackenzie G Williams et al.
Langmuir : the ACS journal of surfaces and colloids, 33(5), 1121-1131 (2017-02-09)
The covalent attachment of nonfunctionalized and carboxylic acid-functionalized carbon nanotubes to amine-terminated organic monolayers on gold and silicon surfaces is investigated. It is well established that the condensation reaction between a carboxylic acid and an amine is a viable method...
Jiyoon Kwak et al.
Veterinary ophthalmology, 20(1), 34-39 (2016-01-06)
This study was designed to evaluate the changes in intraocular pressure (IOP), pupil diameter (PD), and anterior segment parameters using ultrasound biomicroscopy (UBM) after instillation of preservative-free (PF) tafluprost in normal dogs. Six beagle dogs were used. PF tafluprost was...
Methods report: European S3-Guideline on the systemic treatment of psoriasis vulgaris - Update Apremilast and Secukinumab - EDF in cooperation with EADV and IPC.
C Dressler et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 31(12), 1964-1977 (2017-09-26)
Peyman Hadji et al.
Journal of bone oncology, 7, 1-12 (2017-04-18)
Several guidelines have been reported for bone-directed treatment in women with early breast cancer (EBC) for averting fractures, particularly during aromatase inhibitor (AI) therapy. Recently, a number of studies on additional fracture related risk factors, new treatment options as well...
Small, water-soluble, ligand-stabilized gold nanoparticles synthesized by interfacial ligand exchange reactions
Warner MG
Chemistry of Materials, 12(11), 3316-3320 (2000)
Ee Taek Hwang et al.
ChemElectroChem, 4(8), 1959-1968 (2017-09-19)
Coupling light-harvesting semiconducting nanoparticles (NPs) with redox enzymes has been shown to create artificial photosynthetic systems that hold promise for the synthesis of solar fuels. High quantum yields require efficient electron transfer from the nanoparticle to the redox protein, a...
Liran Yang et al.
Neural networks : the official journal of the International Neural Network Society, 124, 60-74 (2020-01-27)
In many practical applications, the assumption that the distributions of the data employed for training and test are identical is rarely valid, which would result in a rapid decline in performance. To address this problem, the domain adaptation strategy has...
Samurailatpam Sanjukta et al.
Food research international (Ottawa, Ont.), 141, 110161-110161 (2021-03-02)
Kinema is an alkaline traditionally fermented soybean product popularly consumed in Sikkim Himalayan region. Kinema was prepared by soybean fermented with different species of Bacillus and analyzed for peptide content, antioxidant activity and consequence of gastrointestinal enzymes (pepsin and pancreatin)...
Alfredo Damasceno et al.
Multiple sclerosis and related disorders, 46, 102513-102513 (2020-10-12)
The demand for better outcome measures in multiple sclerosis (MS) management has been increasingly recognized. Nevertheless, the prognostic impacts of available outcome measures for long-term clinical and especially cognitive disability have not been thoroughly investigated. We, therefore, aimed to explore...
Stimuli-responsive nanoparticles from ionic cellulose derivatives
Wang Y
Nanoscale, 8(1), 648-657 (2016)
Philip R Lindstedt et al.
Cell chemical biology, 28(1), 70-77 (2020-11-21)
Great advances have been made over the last four decades in therapeutic and diagnostic applications of antibodies. The activity maturation of antibody candidates, however, remains a significant challenge. To address this problem, we present a method that enables the systematic...
Kseniya Barinova et al.
Biochimica et biophysica acta. Proteins and proteomics, 1867(4), 396-404 (2019-01-15)
Numerous investigations point to the relation between diabetes and neurodegenerative disorders. Alpha-synuclein is a protein involved in the development of synucleinopathies including Parkinson's disease. In the present work, alpha-synuclein was for the first time modified by the intermediate product of...
Marta Consuegra-Fernández et al.
Cellular & molecular immunology, 15(10), 898-906 (2017-12-12)
Psoriasis is a chronic inflammatory skin disease with a strong genetic background and is triggered by environmental factors. Available evidence supports CD6, a lymphocyte surface receptor mostly expressed by T cells, as a putative target in autoimmunity. Accordingly, a humanized...
Hye-In Kang et al.
Analytica chimica acta, 852, 168-173 (2014-12-03)
A gas chromatography-tandem mass spectrometric (GC-MS/MS) method has been established for the determination of cyanide in surface water. This method is based on the derivatization of cyanide with 2-(dimethylamino)ethanethiol in surface water. The following optimum reaction conditions were established: reagent...