Showing 1-30 of 154 results for "D208000"
Michaël L Cartron et al.
Antimicrobial agents and chemotherapy, 58(7), 3599-3609 (2014-04-09)
Human skin fatty acids are a potent aspect of our innate defenses, giving surface protection against potentially invasive organisms. They provide an important parameter in determining the ecology of the skin microflora, and alterations can lead to increased colonization by...
Keishi Suga et al.
Langmuir : the ACS journal of surfaces and colloids, 29(6), 1899-1907 (2013-01-18)
The effect of cationic liposomes (CLs) on messenger RNA(mRNA) conformation and translation was studied, focusing on membrane heterogeneity. CLs, composed of 1,2-dioleoyl-sn-glycerol-3-phosphocholine/1,2-dioleoyl-3-timethylammonium propane (DOPC/DOTAP) and DOPC/3β-{N-[(N',N'-dimethylamino)ethyl]carbamoyl}cholesterol (DOPC/DC-Ch), inhibited mRNA translation in an Escherichia coli cell-free translation system. Analysis of the...
Romina María Uranga et al.
Molecular neurobiology, 54(5), 3236-3252 (2016-04-16)
We have previously demonstrated that oligomeric amyloid β peptide (oAβ) together with iron overload generates synaptic injury and activation of several signaling cascades. In this work, we characterized hippocampal neuronal response to oAβ. HT22 neurons exposed to 500 nM oAβ showed...
Jack L-Y Chen et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 23(48), 11549-11559 (2017-05-26)
The next generation of adaptive, intelligent chemical systems will rely on a continuous supply of energy to maintain the functional state. Such systems will require chemical methodology that provides precise control over the energy dissipation process, and thus, the lifetime...
Rossella Laurano et al.
Polymers, 11(12) (2020-01-01)
Plasma treatment is a widely applied, easy, fast, and highly reproducible surface modification technique. In this work powder plasma treatment was exploited to expose carboxylic groups along the backbone of a water soluble polymer. Specifically, a custom-made amphiphilic poly(ether urethane)...
Karla Petit et al.
Toxicology in vitro : an international journal published in association with BIBRA, 68, 104964-104964 (2020-08-18)
Epirubicin is a cytotoxic drug used in the treatment of different types of cancer and increasing evidence suggests that its target is cell membranes. In order to gain insight on its toxic effects, intact red blood cells (RBC), human erythrocyte...
Paulina Strugała et al.
Food & function, 12(3), 1271-1290 (2021-01-13)
The aim of the study was to broadly determine the biological activities of purple potato ethanolic extract of the Blue Congo variety (BCE). The antioxidant activity of BCE was determined in relation to liposome membranes, and peroxidation was induced by...
Rita Ghosh et al.
Langmuir : the ACS journal of surfaces and colloids, 36(21), 5829-5838 (2020-05-12)
PEGylated vesicles are known to serve as blood-persistent drug-delivery systems (DDSs) with potential applications in intravenous drug administration. pH-responsive PEGylated vesicles are also among the most promising stimuli-responsive carriers for drug delivery and controlled release for cancer chemotherapy. Herein, we...
Priyadarshini Pathak et al.
Biophysical journal, 101(10), 2417-2425 (2011-11-22)
Mixtures of unsaturated lipids, sphingolipids, and cholesterol form coexisting liquid-disordered and sphingolipid and cholesterol-rich liquid-ordered (Lo) phases in water. The detergent Triton X-100 does not readily solubilize Lo domains, but does solubilize liquid-disordered domains, and is commonly used to prepare...
Johnna Wellman St Clair et al.
Biochimica et biophysica acta. Biomembranes, 1861(6), 1112-1122 (2019-03-25)
Sterol structure influences liquid ordered domains in membranes, and the dependence of biological functions on sterol structure can help identify processes dependent on ordered domains. In this study we compared the effect of sterol structure on ordered domain formation in...
Kervin O Evans et al.
Molecules (Basel, Switzerland), 25(17) (2020-08-23)
α-Glucans that were enzymatically synthesized from sucrose using glucansucrase cloned from Leuconostoc mesenteroides NRRL B-1118 were found to have a glass transition temperature of approximately 80 °C. Using high-pressure homogenization (~70 MPa), the α-glucans were converted into nanoparticles of ~120...
Noemí Fabelo et al.
Neurobiology of aging, 35(8), 1801-1812 (2014-03-13)
The presence of lipid alterations in lipid rafts from the frontal cortex in late stages of Alzheimer's disease (AD) has been recently demonstrated. Here, we have isolated and analyzed the lipid composition of lipid rafts from different brain areas from...
Elena A Lapshina et al.
Cell biochemistry and function, 33(4), 202-210 (2015-05-13)
The present study was undertaken for further elucidation of the mechanisms of flavonoid biological activity, focusing on the antioxidative and protective effects of cranberry flavonoids in free radical-generating systems and those on mitochondrial ultrastructure during carbon tetrachloride-induced rat intoxication. Treatment...
Shen Wang et al.
Protein science : a publication of the Protein Society, 29(6), 1511-1523 (2020-04-12)
Atg3-catalyzed transferring of Atg8 to phosphatidylethanolamine (PE) in the phagophore membrane is essential for autophagy. Previous studies have demonstrated that this process requires Atg3 to interact with the phagophore membrane via its N-terminal amphipathic helix. In this study, by using...
Hyemin Choi et al.
Biochimica et biophysica acta, 1818(7), 1648-1655 (2012-03-13)
The aims of this study wereto investigate the antifungal activity as a bioactive property of dihydrodehydro-diconiferyl alcohol 9'-O-3-D-glucoside (DDDC9G) and the mode of action(s) involved in its effect. Antifungal susceptibility testing showed that DDDC9G possessed potent antifungal activities toward various...
Naomi Hamada et al.
Biochimica et biophysica acta. Biomembranes, 1863(4), 183552-183552 (2021-01-15)
The fluidity and polar environment of ~100 nm hybrid vesicles combining dipalmitoylphosphatidylcholine (DPPC) and poly(1,2-butadiene)-block-polyethylene oxide (PBd-PEO, average molecular weight 950 g/mol) were studied upon vesicle heating using the fluorescence spectroscopy techniques of DPH anisotropy and laurdan generalized polarization (GP). These techniques...
Max V Ranall et al.
BioTechniques, 51(1), 35-36 (2011-07-26)
Neutral lipid droplets (LDs) are dynamic lipid storage organelles found in all eukaryotic cells from yeast to mammals and higher plants. LDs are important to many physiological processes that include basic cellular maintenance, metabolism, and diverse medical pathologies. LD accumulation...
Jaeyong Cho et al.
Journal of microbiology and biotechnology, 22(10), 1367-1374 (2012-10-19)
Pleurocidin, a 25-mer antimicrobial peptide, has been known to exhibit potent antibacterial activity. To investigate the functional roles in N- and C-terminal regions of pleurocidin on the antibacterial activity, we designed four truncated analogs. The antibacterial susceptibility testing showed that...
Xiaoli Liu et al.
Carbohydrate polymers, 182, 225-234 (2017-12-28)
Here, a nontoxic antibacterial material based on Chitosan Oligosaccharide-N-Chlorokojic acid Mannich base (COS-N-MB) that was synthesized by using the selective partial alkylation reaction displaying excellent activity against bacterial infection. The proposed mechanism of the action of COS-N-MB is that this...
Xuqian Li et al.
Acta biomaterialia, 106, 301-313 (2020-02-23)
Corosolic acid (CA), a natural pentacyclic triterpenoid, exhibits antitumor and synergistic therapy effect with chemotherapeutic drugs mainly through inhibiting STAT3 activation. In this study, it is found that CA possesses cholesterol-like properties in liposome by regulating membrane phase behavior to...
Selma Yilmaz Dejgaard et al.
Biochemical and biophysical research communications, 520(3), 526-531 (2019-10-16)
Rab18 is a small GTPase associated with lipid droplets and other membranes. While it likely has multiple functions on lipid droplets, one proposed function is regulation of lipolysis. Previous work has concentrated on regulation of autophagy; however, in this study...
José R Colina et al.
Archives of biochemistry and biophysics, 662, 75-82 (2018-12-12)
The interaction and protective effect of caffeic acid (CA) on human erythrocytes (RBC) and molecular models of its membrane were studied. The latter consisted of bilayers built up of dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylethanolamine (DMPE), representative of phospholipid classes located in...
Luis F Aguilar et al.
PloS one, 7(6), e40254-e40254 (2012-07-07)
Changes in the cholesterol (Chol) content of biological membranes are known to alter the physicochemical properties of the lipid lamella and consequently the function of membrane-associated enzymes. To characterize these changes, we used steady-state and time resolved fluorescence spectroscopy and...
Tae-Rim Choi et al.
Journal of industrial microbiology & biotechnology, 47(12), 1045-1057 (2020-12-02)
Psychrophilic bacteria, living at low and mild temperatures, can contribute significantly to our understanding of microbial responses to temperature, markedly occurring in the bacterial membrane. Here, a newly isolated strain, Pseudomonas sp. B14-6, was found to dynamically change its unsaturated...
Ion Hurjui et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 102, 219-225 (2012-12-12)
The electronic absorption spectra of 1,6-diphenyl-1,3,5-hexatriene (DPH) were recorded in a great number of solvents with various physico-chemical properties. The dependence of the wavenumber in the maximum of the DPH vibronic bands on the solvent dispersion function demonstrates the prevalence...
Chenyang Li et al.
Frontiers in microbiology, 10, 3037-3037 (2020-02-11)
Yersinia enterocolitica, a zoonotic foodborne pathogen, is able to withstand low temperatures. This psychrotrophic ability allows it to multiply in food stored in refrigerators. However, little is known about the Y. enterocolitica cold response. In this study, isolate-specific behavior at...
Hyun Jung Lee et al.
Small (Weinheim an der Bergstrasse, Germany), 16(12), e1903045-e1903045 (2019-09-17)
A reactive oxygen species (ROS)-sensitive degradable polymer would be a promising material in designing a disease-responsive system or accelerating degradation of polymers with slow hydrolysis kinetics. Here, a thermogelling poly(ethylene glycol)-polycaprolactone-poly(ethylene glycol) (PEG-PCL-PEG or EG12 -CL20 -EG12 ) triblock copolymer...
Eugenia Kovács et al.
Bioelectrochemistry (Amsterdam, Netherlands), 87, 230-235 (2012-04-24)
The interaction of positively-charged antibiotic gentamicin with cell membranes was studied to determine if any changes in membrane organization were induced by the drug. Opossum kidney epithelia (OK) cells were used as models of eukaryotic cells. Two methods were used:...
Dendrimer-based micelles with highly potent targeting to sites of active bone turnover for the treatment of bone metastasis.
Yamashita, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 157, 85-96 (2020)
Simone Rodrigues Silva et al.
Bioinorganic chemistry and applications, 2015, 942147-942147 (2015-09-09)
Complexes of gadolinium(III) with N-octanoyl-N-methylglucamine (L8) and N-decanoyl-N-methylglucamine (L10) with 1 : 2 stoichiometry were synthesized and characterized by elemental analysis, electrospray ionization-tandem mass spectrometry (ESI-MS), infrared (IR) spectroscopy, and molar conductivity measurements. The transverse (r 2) and longitudinal (r 1) relaxivity...

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