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Xuejiao Gao et al.
Nature communications, 9(1), 118-118 (2018-01-11)
It is known that self-assembled molecular monolayer doping technique has the advantages of forming ultra-shallow junctions and introducing minimal defects in semiconductors. In this paper, we report however the formation of carbon-related defects in the molecular monolayer-doped silicon as detected...
Wei Feng et al.
Scientific reports, 5, 17422-17422 (2015-12-04)
Photothermal cancer therapy has attracted considerable interest for cancer treatment in recent years, but the effective photothermal agents remain to be explored before this strategy can be applied clinically. In this study, we therefore develop flower-like molybdenum disulfide (MoS2) nanoflakes...
Bin Ni et al.
Macromolecular rapid communications, 41(19), e2000385-e2000385 (2020-08-20)
The research on soft actuators including liquid crystal elastomers (LCEs) becomes more and more appealing at a time when the expansion of artificial systems is blooming. Among the various LCE actuators, the bending deformation is often in the origin of...
Heghine Torgomyan et al.
Cell biochemistry and biophysics, 62(3), 451-461 (2011-11-22)
Escherichia coli K-12(λ) was sensitive toward low-intensity (non-thermal, flux capacity 0.06 mW cm(-2)) electromagnetic irradiation (EMI) of extremely high frequency-70.6 and 73 GHz. 1 h exposure to EMI markedly depressed growth and cell viability of bacteria. Membrane-associated processes-total H(+) efflux...
Sean T Byrne et al.
Antimicrobial agents and chemotherapy, 51(12), 4495-4497 (2007-09-19)
Diethyldithiocarbamate (DETC) and pyrrolidine dithiocarbamate (PDTC) were highly active against tubercle bacilli, with MICs of 8 microg/ml and 0.13 microg/ml, respectively. DETC and PDTC were active against old cultures, enhanced pyrazinamide or pyrazinamide/rifampin activity, and had serum inhibitory titers of...
Saskia Villinger et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(52), 22546-22551 (2010-12-15)
The voltage-dependent anion channel (VDAC), located in the outer mitochondrial membrane, acts as a gatekeeper for the entry and exit of mitochondrial metabolites. Here we reveal functional dynamics of isoform one of VDAC (VDAC1) by a combination of solution NMR...
Cycloadditions of N, N'-dicyclohexylcarbodiimide to 2-phenylethenyl isothiocyanates.
Hritzova O
Collection of Czechoslovak Chemical Communications, 48(6), 1745-1748 (1983)
Zaruhi Vardanyan et al.
Biochemical and biophysical research communications, 417(1), 541-545 (2011-12-15)
Enterococcus hirae is able to grow under anaerobic conditions during glucose fermentation (pH 8.0) which is accompanied by acidification of the medium and drop in its oxidation-reduction potential (E(h)) from positive values to negative ones (down to ∼-200 mV). In...
Sher Bahadar Khan et al.
Journal of enzyme inhibition and medicinal chemistry, 25(6), 812-817 (2010-05-19)
A series of benzoic acid derivatives 1-10 have been synthesised by two different methods. Compounds 1-6 were synthesised by a facile procedure for esterification using N,N'-dicyclohexylcarbodiimide (DCC) as a coupling agent, methylene chloride as a solvent system and dimethylaminopyridine (DMAP)....
Nir Fluman et al.
Molecular cell, 47(5), 777-787 (2012-07-31)
Multidrug transporters are ubiquitous efflux pumps that provide cells with defense against various toxic compounds. In bacteria, which typically harbor numerous multidrug transporter genes, the majority function as secondary multidrug/proton antiporters. Proton-coupled secondary transport is a fundamental process that is...
Fabrício Figueiró et al.
Journal of biomedical nanotechnology, 11(10), 1808-1818 (2015-10-28)
Glioblastoma multiforme is a devastating cerebral tumor with an exceedingly poor prognosis. Methotrexate (MTX) is a folic acid analogue that inhibits DNA synthesis by binding to dihydrofolate reductase. Biodegradable nanoparticles are emerging as a promising system for drug delivery to...
H Torgomyan
Indian journal of biochemistry & biophysics, 49(6), 428-434 (2013-01-29)
The effects of low intensity (flux capacity 0.06 mW/cm2) coherent electromagnetic irradiation (EMI) of 70.6 and 73 GHz frequencies and their combined effects with antibiotics--ceftriaxone or kanamycin (0.4 or 15 microM, correspondingly) on E. coli K12 growth and survival have...
Juan L Paris et al.
ACS nano, 9(11), 11023-11033 (2015-10-13)
A new ultrasound-responsive system based on mesoporous silica nanoparticles was developed for biomedical applications, grafting a copolymer on their surface that acts as gatekeeper of the pores. The nanoparticles can be loaded with a cargo at low temperature (4 °C)...
Ji-Feng Shi et al.
Journal of biomedical nanotechnology, 11(9), 1568-1582 (2015-10-22)
Regular chemotherapy cannot eradicate invasive breast cancer cells and the residual cancer cells will form vasculogenic mimicry (VM) channels under hypoxic conditions to provide nutrients for cancer masses prior to angiogenesis. This phenomenon is a major reason for the recurrence...
Yunfei Zhang et al.
Journal of colloid and interface science, 528, 27-35 (2018-05-29)
We introduce 10,12-Pentacosadiynoic acid conjugated with pyridine-2-aldoxime (pralidoxime, PAM) as a positively charged amphiphilic molecule capable of forming a polymer with polydiacetylene (PDA-PAM) via 1,4-addition photopolymerization of self-assembled PAM-modified monomers. Colloidally stabilized vesicles formed by PDA-PAM and unmodified pentacosadiynoic acid...
Karen Trchounian
Gene, 506(1), 156-160 (2012-07-10)
Escherichia coli molecular hydrogen (H(2)) production was studied during mixed carbon (glucose and glycerol) fermentation at pH 6.5. Wild type cells in the assays supplemented with glucose produced H(2) at ~2 fold lower level than cells grown on glucose only....
Mallaredy Vandana et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 94, 83-93 (2015-05-15)
Combination therapy in cancer is now opted as a potential therapeutic strategy for cancer treatment. However, effective delivery of drugs in combination at the tumor site is marred by low bioavailability and systemic toxicity of individual drugs. Polymer therapeutics is...
Dharmesh R Chejara et al.
Carbohydrate polymers, 135, 324-333 (2015-10-11)
In this article a novel bio-injectable algin-aminocaproic acid (Alg-ACA) tri-stimuli responsive thixogel system is reported. The designed soft thixotrophic hydrogel (thixogel) was characterized using various analytical techniques such as FT-IR, NMR, SEM, AFM and DSC. The soft thixogel system was...
Chao Wang et al.
The Analyst, 144(5), 1590-1599 (2019-01-05)
Herein, we describe a competitive-type electrochemiluminescence (ECL) strategy for Hg2+ determination based on the peroxydisulfate/oxygen (S2O82-/O2) system that uses Pt/Pd nanodendrites (Pt/Pd NDs)-thiosemicarbazide/norfloxacin (TN)-covered gold nanoparticles (Pt/Pd-TNG50) as a signal enhancer. The Pt/Pd NDs, a dense array of Pt branches...
Eli Vlaisavljevich et al.
Ultrasound in medicine & biology, 42(4), 931-946 (2016-01-18)
Nanodroplet-mediated histotripsy (NMH) is a targeted ablation technique combining histotripsy with nanodroplets that can be selectively delivered to tumor cells. In two previous studies, polymer-encapsulated perfluoropentane nanodroplets were used to generate well-defined ablation similar to that obtained with histotripsy, but...
Maria-Teresa Weichler et al.
Applied and environmental microbiology, 81(14), 4564-4572 (2015-04-26)
The recent discovery of a coenzyme B12-dependent acyl-coenzyme A (acyl-CoA) mutase isomerizing 3-hydroxybutyryl- and 2-hydroxyisobutyryl-CoA in the mesophilic bacterium Aquincola tertiaricarbonis L108 (N. Yaneva, J. Schuster, F. Schäfer, V. Lede, D. Przybylski, T. Paproth, H. Harms, R. H. Müller, and...
Ping Huang et al.
Pharmaceutical research, 32(7), 2328-2343 (2015-01-17)
A novel hydrophilic conjugate of arginine-glycine-aspartic acid (RGD) and polyethylene glycol (PEG), i.e., RGD-PEG Mw (M W = 300, 600, 1000 or 4000), was synthesized and employed in epirubicin (EPI) loaded poly L-lactic acid (PLLA) nanoparticles (NPs) to improve its...
Kun Chen et al.
Scientific reports, 5, 16316-16316 (2015-11-13)
Mercury and its compounds are known to be extremely toxic but widely distributed in environment. Although many works have been reported to efficiently detect mercury, development of simple and convenient sensors is still longed for quick analyzing mercury in water....
James R Lattin et al.
Journal of drug targeting, 23(5), 469-479 (2015-02-13)
Vaporizing emulsion droplets may aid in endosomal rupture as a drug delivery route to the cytosol. Upon insonation, emulsion droplets formed from perfluorocarbon liquids may vaporize with sufficient expansion to disrupt liposomal or endosomal membranes. Emulsion droplets of perfluorohexane (PFC6)...
Yifei Zhang et al.
The AAPS journal, 16(6), 1282-1291 (2014-09-07)
The purpose of this study is to develop an improved drug delivery system for enhanced paclitaxel (PTX) loading capacity and formulation stability based on PEG5K-(vitamin E)2 (PEG5K-VE2) system. PEG5K-(fluorenylmethoxycarbonyl)-(vitamin E)2 (PEG5K-FVE2) was synthesized using lysine as the scaffold. PTX-loaded PEG5K-FVE2...
Reaction of 4-substituted benzoyl isothiocyanates with N, N'-dicyclohexylcarbodiimide and N, N'-diphenylcarbodiimide
Hritzova O
Collection of Czechoslovak Chemical Communications, 43(12), 3258-3262 (1978)
Salvatore Nesci et al.
Biochimie, 93(7), 1157-1164 (2011-05-03)
Tributyltin (TBT), a persistent lipophilic contaminant found especially in the aquatic environment, is known to be toxic to mitochondria with the F(1)F(0)-ATPase as main target. Recently our research group pointed out that in mussel digestive gland mitochondria TBT, apart from...
Yanyan Jiang et al.
Macromolecular bioscience, 15(7), 965-978 (2015-03-27)
A novel gene transfection vector was fabricated based on the conjugation of human serum albumin (HSA) and maleimide end functionalized poly[(N,N-dimethylamino) ethyl methacrylate] (PDMAEMA). The bioconjugation was achieved in a site-specific manner to yield well-defined polymer-protein conjugates. The biohybrid was...
Xian Zhang et al.
Toxicon : official journal of the International Society on Toxinology, 106, 89-96 (2015-09-28)
Ochratoxin A (OTA) is one of the most commonly occurring mycotoxins produced by some species of Aspergillus and can contaminate cereal and cereal products. A high-affinity anti-OTA monoclonal antibody (mAb) was generated from a hybridoma cell line 2D8 using splenocytes...
Xi Zhan et al.
Pharmaceutical research, 32(7), 2280-2291 (2015-01-17)
A key step of delivering extracellular agents to its intracellular target is to escape from endosomal/lysosomal compartments, while minimizing the release of digestive enzymes that may compromise cellular functions. In this study, we examined the intracellular distribution of both fluorecent...
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