Showing 1-30 of 204 results for "E4250"
Elizabeth Calderón et al.
Puerto Rico health sciences journal, 32(4), 170-174 (2014-01-09)
Anaphylaxis is a severe, potentially life-threatening systemic allergic reaction. Most cases of anaphylaxis are encountered and managed at Emergency Departments (ED). We aimed to evaluate all cases of anaphylaxis and of acute allergic reactions presenting to the ED of the...
B X E Desbiolles et al.
Nano letters, 19(9), 6173-6181 (2019-08-20)
Micronanotechnology-based multielectrode arrays have led to remarkable progress in the field of transmembrane voltage recording of excitable cells. However, providing long-term optoporation- or electroporation-free intracellular access remains a considerable challenge. In this study, a novel type of nanopatterned volcano-shaped microelectrode...
Prashanth Sirigeri Jois et al.
Reproductive biology and endocrinology : RB&E, 13, 64-64 (2015-06-19)
Bovine BSP5 is a multifunctional protein primarily involved in sperm capacitation. BSP5 consists of long N-terminal part followed by two similar and highly conserved fibronectin type II domains designated A and B. In order to assess the role of these...
A review of epinephrine administration in pediatric anaphylaxis.
Wendy J Hemme
Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association, 38(4), 392-397 (2012-04-13)
Epinephrine for cardiac arrest: are we doing more harm than good?
Vijay Krishnamoorthy et al.
Anesthesiology, 120(4), 792-794 (2013-10-19)
Huang Yu et al.
The American journal of emergency medicine, 31(7), 1022-1028 (2013-05-22)
Cytidine diphosphate choline (CDP-choline) is a cholinergic agent that can both stimulate the cholinergic pathway and increase blood pressure. We aimed to investigate the effects of CDP-choline on the outcome of cardiac arrest in comparison with epinephrine. This was a...
Mark M Kushnir et al.
Clinical chemistry, 52(8), 1559-1567 (2006-06-17)
Congenital adrenal hyperplasia is a group of autosomal recessive disorders caused by a deficiency of 1 of 4 enzymes required for the synthesis of glucocorticoids, mineralocorticoids, and sex hormones. Analysis of 11-deoxycortisol (11DC), 17-hydroxyprogesterone (17OHP), 17-hydroxypregnenolone (17OHPr), and pregnenolone (Pr)...
Epinephrine: the drug of choice for anaphylaxis.
Sally Schoessler
NASN school nurse (Print), 28(1), 52-52 (2013-06-04)
Inhaled adrenaline in acute bronchiolitis.
Ricardo G Branco et al.
The New England journal of medicine, 369(11), 1075-1076 (2013-09-13)
Is adrenaline safe and effective as a treatment for out of hospital cardiac arrest?
Gavin D Perkins et al.
BMJ (Clinical research ed.), 348, g2435-g2435 (2014-04-09)
Akihiko Urayama et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(31), 12873-12878 (2007-07-25)
Delivering therapeutic levels of lysosomal enzymes across the blood-brain barrier (BBB) has been a pivotal issue in treating CNS storage diseases, including the mucopolysaccharidoses. An inherited deficiency of beta-glucuronidase (GUS) causes mucopolysaccharidosis type VII that is characterized by increased systemic...
The time-sensitive role of vasopressors during resuscitation of ventricular fibrillation.
Gordon A Ewy
Journal of the American College of Cardiology, 64(22), 2368-2370 (2014-12-04)
Eva Pállinger et al.
Acta microbiologica et immunologica Hungarica, 60(4), 423-431 (2013-12-03)
Immune cells synthesize, store and secrete hormones, the level of which changes in ALL. In previous experiments the level of histamine, serotonin and triiodothyronine (T3)was studied, while at present that of ACTH, insulin and epinephrine, using flow cytometric analysis for...
Cheryl M Soref et al.
International journal of cancer, 136(1), 195-203 (2014-05-09)
In a new strategy, we sought to determine whether topically applied vasoconstrictor, with its accompanying transient skin hypoxia and exclusion of systemic drug, would prevent or suppress radiotherapy or chemotherapy-induced alopecia. Topical vasoconstrictor was applied to 1-cm(2) skin patches on...
[Therapy of anaphylaxis].
Martin Meyer et al.
Praxis, 103(10), 555-562 (2014-05-08)
Martin Botha et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 103(10), 713-714 (2013-10-02)
Despite the recognition of specialists in emergency medicine and the professionalisation of prehospital emergency care, international guidelines and consensus are often ignored, and the lag between guideline publication and translation into clinical practice is protracted. South African literature should reflect...
Yutaka Kondo et al.
Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 26(4), 295-299 (2014-02-04)
Cyanamide is a known alcohol deterrent, and it may cause severe cyanamide-ethanol reaction if a patient consumes high amounts of alcohol during treatment. We report a rare case of cyanamide-ethanol reaction-induced shock in a 73-year-old man who was taking cyanamide...
Eun-Min Kim et al.
PLoS neglected tropical diseases, 13(4), e0006843-e0006843 (2019-04-04)
Clonorchis sinensis is a group I bio-carcinogen responsible for cholangiocarcinoma (CHCA) in humans. However, the mechanism by which C. sinensis promotes carcinogenesis is unclear. Using the human cholangiocyte line H69, we investigated cell proliferation and gap junction protein expression after...
Jørgen Jensen et al.
Archives of physiology and biochemistry, 115(1), 13-21 (2009-03-10)
In mammals, excess carbohydrate is stored as glycogen and glycogen synthase is the enzyme that incorporates glucose units into the glycogen particle. Glycogen synthase activity is regulated by phosphorylation and allosterically activated by glucose 6-phosphate. Phosphorylation of nine serines by...
Vilhjalmur Finsen
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 133(17), 1827-1830 (2013-09-18)
It is often maintained that a local anaesthetic (usually lidocaine) with adrenaline must not be used in fingers and toes because it may cause necrosis due to vascular spasm in end arteries. This review article is an attempt to find...
Long-term stability of epinephrine sublingual tablets for the potential first-aid treatment of anaphylaxis.
Mutasem M Rawas-Qalaji et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 111(6), 568-570 (2013-11-26)
S R Bornstein et al.
Clinical endocrinology, 42(2), 215-218 (1995-02-01)
Two endocrine tissues are present within the adrenal gland: the steroid producing cortical cells and the catecholamine producing chromaffin cells. Glucocorticoids occur in high concentrations in the adrenal medulla. In vitro, glucocorticoids have been shown to induce the enzyme phenyl-N-methyl-transferase...
Heat stress affects some physiological and productive variables and alters metabolism in dairy ewes.
Mehaba, et al.
Journal of Dairy Science, 104, 1099-1110 (2021)
B S Wilson et al.
Cancer research, 50(10), 3124-3130 (1990-05-15)
The murine monoclonal antibody LS2D617, which reacts with an antigen associated with human small cell lung carcinoma (SCLC), was tested in preclinical models to assess its potential for specific targeting of tumors in human SCLC cancer patients. LS2D617 detects a...
Mathieu Pasquier et al.
Revue medicale suisse, 9(392), 1386-1391 (2013-07-26)
Clifton W Callaway
Current opinion in cardiology, 28(1), 36-42 (2012-12-01)
Epinephrine is the primary drug administered during cardiopulmonary resuscitation (CPR) to reverse cardiac arrest. Epinephrine increases arterial blood pressure and coronary perfusion during CPR via alpha-1-adrenoceptor agonist effects. However, the dose, timing and indications for epinephrine use are based on...
Popchai Ngamskulrungroj et al.
PloS one, 6(1), e16076-e16076 (2011-01-21)
Human and animal cryptococcosis due to an unusual molecular type of Cryptococcus gattii (VGII) emerged recently on Vancouver Island, Canada. Unlike C. neoformans, C. gattii causes disease mainly in immunocompetent hosts, despite producing a similar suite of virulence determinants. To...
M de Queiroz Siqueira et al.
British journal of anaesthesia, 112(4), 729-734 (2013-10-05)
The optimal dosing regimens of lipid emulsion, epinephrine, or both are not yet determined in neonates in cases of local anaesthetic systemic toxicity (LAST). Newborn piglets received levobupivacaine until cardiovascular collapse occurred. Standard cardiopulmonary resuscitation was started and electrocardiogram (ECG)...
Gemma K Kinsella et al.
Bioorganic & medicinal chemistry, 15(8), 2850-2855 (2007-03-06)
In order to design any new potential drug, it is crucial to know their corresponding pK(a) since their protonation state will be critical in the ligand-receptor interaction and it will play an essential role in their pharmacokinetic profile. Several authors...
Leobardo Manuel Gómez-Oliván et al.
Environmental monitoring and assessment, 186(11), 7259-7271 (2014-07-10)
Toxicity in natural ecosystems is usually not due to exposure to a single substance, but is rather the result of exposure to mixtures of toxic substances. Knowing the effects of contaminants as a mixture compared to their effects in isolated...

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