egfr inhibitor

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EGFR Inhibitor

Synonym(s): EGFR Inhibitor

Empirical Formula (Hill Notation): C₂₁H₁₈F₃N₅O

CAS No.:: 879127-07-8
Molecular Weight:: 413.40

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	324674	The EGFR Inhibitor, also referenced under CAS 879127-07-8, controls the biological activity of EGFR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

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EGFR/ErbB-2 Inhibitor

Synonym(s): EGFR/ErbB-2 Inhibitor

Empirical Formula (Hill Notation): C₂₃H₂₁N₃O₃

CAS No.:: 179248-61-4
Molecular Weight:: 387.43

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	324673	The EGFR/ErbB-2 Inhibitor, also referenced under CAS 179248-61-4, controls the biological activity of EGFR/ErbB-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

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EGFR Inhibitor II, BIBX1382

Synonym(s): EGFR Inhibitor II, BIBX1382

Empirical Formula (Hill Notation): C₁₈H₁₉ClFN₇ · 2HCl · 2H₂O

CAS No.:: 196612-93-8
Molecular Weight:: 496.79

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	324832	The EGFR Inhibitor II, BIBX1382, also referenced under CAS 196612-93-8, controls the biological activity of EGFR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

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Mutant EGFR inhibitor

CAS No.:: 1421373-62-7
Molecular Weight:: 520.03

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	AMBH9A9040BA

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EGFR/ErbB-2 inhibitor-1

CAS No.:: 1135150-79-6
Molecular Weight:: 467.97

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	TA9H9A1D13F5

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EGFR/ErbB-2/ErbB-4 inhibitor-2

CAS No.:: 179248-61-4
Molecular Weight:: 387.44

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	TA9H97BAEA91

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EGFR/ErbB-2/ErbB-4 inhibitor-3

CAS No.:: 881001-19-0
Molecular Weight:: 355.76

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	AABH97D2BD4C

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AG490

Synonym(s): InSolution AG490

Empirical Formula (Hill Notation): C₁₇H₁₄N₂O₃

Molecular Weight:: 294.30

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	658411	InSolution, ≥98%, inhibitor of EGFR kinase autophosphorylation

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Gefitinib

Empirical Formula (Hill Notation): C₂₂H₂₄ClFN₄O₃

CAS No.:: 184475-35-2
Molecular Weight:: 446.90

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	SML1657	≥98% (HPLC), powder, EGFR TK inhibitor

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PD 158780

Synonym(s): PD 158780

Empirical Formula (Hill Notation): C₁₄H₁₂BrN₅

CAS No.:: 171179-06-9
Molecular Weight:: 330.18

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	513035	A potent, cell-permeable, reversible, ATP-competitive inhibitor of the EGFR tyrosine kinase activity (IC₅₀ = 8 pM).

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CL-387,785

Synonym(s): CL-387,785

Empirical Formula (Hill Notation): C₁₈H₁₃BrN₄O

CAS No.:: 194423-06-8
Molecular Weight:: 381.23

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	233100	A cell-permeable and irreversible inhibitor of EGF-receptor (EGFR) kinase activity in vivo (IC₅₀ = 250-490 pM) as well as EGF-stimulated autophosphorylation of tyrosine residues in the EGFR in vivo (IC₅₀ = 5 nM).

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PD 168393

Synonym(s): PD 168393

Empirical Formula (Hill Notation): C₁₇H₁₃BrN₄O

CAS No.:: 194423-15-9
Molecular Weight:: 369.22

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	513033	A potent, cell-permeable, irreversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC₅₀ = 700 pM).

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PD 174265

Synonym(s): PD 174265

Empirical Formula (Hill Notation): C₁₇H₁₅BrN₄O

CAS No.:: 216163-53-0
Molecular Weight:: 371.23

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	513040-M	A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC₅₀ = 450 pM).

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TX-1123

Synonym(s): TX-1123

Empirical Formula (Hill Notation): C₂₀H₂₄O₃

CAS No.:: 157397-06-3
Molecular Weight:: 312.40

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	655200	A cell-permeable, reversible, and substrate-competitive arylidene-cyclopentenedione derived tyrphostin that acts as an inhibitor for Src, eEF2-K, and PKA, and EGFR-K/PKC at much higher concentrations.

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PD 153035

Synonym(s): PD 153035

Empirical Formula (Hill Notation): C₁₆H₁₄BrN₃O₂

CAS No.:: 153436-54-5
Molecular Weight:: 360.21

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	234490	An extremely potent, cell-permeamble, reversible, ATP-competitive and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC₅₀ = 25 pM; K_i = 6 pM).

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Reveromycin A

Empirical Formula (Hill Notation): C₃₆H₅₂O₁₁

CAS No.:: 134615-37-5
Molecular Weight:: 660.79

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	R0654	solid, suitable for cell culture, BioReagent

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Tyrphostin 23

Synonym(s): (3,4-Dihydroxybenzylidene)malononitrile, RG-50810

Empirical Formula (Hill Notation): C₁₀H₆N₂O₂

CAS No.:: 118409-57-7
Molecular Weight:: 186.17

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	T7165	≥98%

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Curcumin

Synonym(s): (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane, Diferulylmethane, Natural Yellow 3

Linear Formula: [HOC₆H₃(OCH₃)CH=CHCO]₂CH₂

CAS No.:: 458-37-7
Molecular Weight:: 368.38
EC No.:: 207-280-5
Beilstein No.:: 2306965

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	C7727	≥94% (curcuminoid content), ≥80% (Curcumin)

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Tyrphostin 51

Synonym(s): 2-Amino-1,1,3-tricyano-4-(3′,4′,5′-trihydroxyphenyl)butadiene

Empirical Formula (Hill Notation): C₁₃H₈N₄O₃

CAS No.:: 126433-07-6
Molecular Weight:: 268.23

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	T7665	≥98%

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Tyrphostin AG 825

Synonym(s): 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide, Tyrphostin C15

Empirical Formula (Hill Notation): C₁₉H₁₅N₃O₃S₂

CAS No.:: 149092-50-2
Molecular Weight:: 397.47

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	T5443	≥92.5%

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GW2974

Synonym(s): N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido[3,4-d]pyrimidine-4,6-diamine

Empirical Formula (Hill Notation): C₂₃H₂₁N₇

CAS No.:: 202272-68-2
Molecular Weight:: 395.46

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	G0668	≥98% (HPLC), solid

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Tyrphostin 1

Synonym(s): (4-Methoxybenzylidene)malononitrile

Linear Formula: CH₃OC₆H₄CH=C(CN)₂

CAS No.:: 2826-26-8
Molecular Weight:: 184.19

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	T7040	≥98%

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Epidermal Growth Factor Receptor human

Synonym(s): EGFR

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	E3641	buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry)

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GW583340 dihydrochloride

Synonym(s): 4-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenylamino]-6-[2-[[2-(methylsulfonyl)ethyl]aminomethyl]-4-thiazolyl]quinazoline dihydrochloride

Empirical Formula (Hill Notation): C₂₈H₂₅ClFN₅O₃S₂ · 2HCl

CAS No.:: 1173023-85-2
Molecular Weight:: 671.03

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	G3545	≥97% (HPLC), solid

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Tyrphostin AG 1478

Synonym(s): N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine

Empirical Formula (Hill Notation): C₁₆H₁₄ClN₃O₂

CAS No.:: 175178-82-2
Molecular Weight:: 315.75

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	T4182	≥98%

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Tyrphostin A9

Synonym(s): Malonoben, [[3,5-bis(1,1-Dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrile

Empirical Formula (Hill Notation): C₁₈H₂₂N₂O

CAS No.:: 10537-47-0
Molecular Weight:: 282.38

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	T182	solid

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Tyrphostin AG 490

Synonym(s): 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(benzyl)-2-propenamide, 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide

Empirical Formula (Hill Notation): C₁₇H₁₄N₂O₃

CAS No.:: 133550-30-8
Molecular Weight:: 294.30

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	T3434	solid

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Bisindolylmaleimide IV

Synonym(s): Ro 31-6233

Empirical Formula (Hill Notation): C₂₀H₁₃N₃O₂

CAS No.:: 119139-23-0
Molecular Weight:: 327.34

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	B3306	≥98% (TLC), solid

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SU 5416

Synonym(s): 1,3-Dihydro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-2H-indol-2-one

Empirical Formula (Hill Notation): C₁₅H₁₄N₂O

CAS No.:: 204005-46-9
Molecular Weight:: 238.28

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	S8442	≥98% (HPLC), powder, neuronal nitric oxide synthase inhibitor

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Synonym(s): 4′,5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Empirical Formula (Hill Notation): C₁₅H₁₀O₅

CAS No.:: 446-72-0
Molecular Weight:: 270.24
EC No.:: 207-174-9
Beilstein No.:: 263823

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	G6776	from Glycine max (soybean), ~98% (HPLC)
	G6649	≥98% (HPLC), powder, tyrosine protein kinase inhibitor

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egfr inhibitor

EGFR Inhibitor

EGFR/ErbB-2 Inhibitor

EGFR Inhibitor II, BIBX1382

Mutant EGFR inhibitor

EGFR/ErbB-2 inhibitor-1

EGFR/ErbB-2/ErbB-4 inhibitor-2

EGFR/ErbB-2/ErbB-4 inhibitor-3

AG490

Gefitinib

PD 158780

CL-387,785

PD 168393

PD 174265

TX-1123

PD 153035

Reveromycin A

Tyrphostin 23

Curcumin

Tyrphostin 51

Tyrphostin AG 825

GW2974

Tyrphostin 1

Epidermal Growth Factor Receptor human

GW583340 dihydrochloride

Tyrphostin AG 1478

Tyrphostin A9

Tyrphostin AG 490

Bisindolylmaleimide IV

SU 5416

Genistein