Showing 1-30 of 65 results for "epigenetics"
Epigenetics
Epigenetic reagents and resources for investigating RNA species, DNA methylation, chromatin modifications, and histone modifications.
Epigenetics
Epigenetics tools and techniques for researching the complexities of epigenetic mechanisms including DNA methylation, histone modification, and RNA regulation.
Epigenetics
Epigenetic reagents and resources for investigating RNA species, DNA methylation, chromatin modifications, and histone modifications.
Carcinogenesis and Epigenetics
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
Epigenetics Overview
Epigenetics is a term coined to describe changes that are not mutation based but can still be passed on from generation to generation. Genes that are activated or repressed without any change in DNA sequence are epigenetically controlled. Epigenetic modifications...
Histone Modification and Chromatin Remodeling | Epigenetics
Epigenetic modifications are thought to occur through two key interconnected processes—DNA methylation and the covalent modification of histones.
Epigenetic Mechanisms in Cancer Pathogenesis
This page reviews some of our newest and most innovative technologies and their specific applications toward cancer research. One is reminded of how complex the disease of cancer is, and how difficult it is to identify one topic that is...
Discover Bioactive Small Molecules for Gene Regulation
We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.
Imprint® Methylated DNA Quantification Kit (MDQ1) Protocol
Imprint <sup>®</sup> Methylated DNA Quantification Kit (<a href="#">MDQ1</a>) Protocol
Introduction to DNA Methylation
Epigenetic regulation starts with DNA wound around a set of completely acetylated histones associated with an activated, fully transcribed gene.
DNA Methylation and Bisulfite Conversion
There are several common ways to determine whether a gene contains methylated DNA. Since mammalian methylation occurs at cytosines, researchers take advantage of the fact that methylated cytosine (meC) is stable to bisulfite treatment but unmethylated cytosine is transformed to...
PCR Supplies & Equipment
PCR tubes, tips, filter tips, plates, plate sealers, PCR thermocyclers and additional consumables to support your PCR workflow.
Whole Genome Amplification
Whole Genome Amplification (WGA) kits, reagents, and protocols to support your WGA workflow.
qPCR
Quantitative PCR (qPCR) or quantitative Real-Time PCR applications, utilizing fluorescent report molecules, suitable for your microRNA, genotyping, and gene expression analyses.
PCR Reagents & Kits
Polymerase Chain Reaction (PCR) is a mainstay in molecular biology labs. PCR is used for amplifying DNA by several orders of magnitude and our reagents and resources are suitable for numerous research workflows including, gene expression analysis, genotyping, sequencing, and...
PCR Applications
Polymerase chain reaction (PCR) is a technique for amplifying nucleic acid molecules and is commonly used in many applications, including RT-PCR, hot start PCR, end point PCR and more.
Roche
Roche Life Science Products - As the exclusive distributor of Roche products and biochemical reagents, we are committed to enabling your next breakthrough by providing dependable reagents that can quickly deliver high-quality, reproducible results.
Whole Genome Amplification
Whole Genome Amplification (WGA) kits, reagents, and protocols to support your WGA workflow.
PCR Reagents & Kits
Polymerase Chain Reaction (PCR) is a mainstay in molecular biology labs. PCR is used for amplifying DNA by several orders of magnitude and our reagents and resources are suitable for numerous research workflows including, gene expression analysis, genotyping, sequencing, and...
PCR Supplies & Equipment
PCR tubes, tips, filter tips, plates, plate sealers, PCR thermocyclers and additional consumables to support your PCR workflow.
Microbiome
Explore our complete package for gut microbiome analysis, including sample preparation, next generation sequencing, downstream bioinformatics, and statistical analysis tools. Our products intuitively integrate into your workflow with 16S analysis of bacteria in fecal samples to whole genome sequencing (WGS).
Rapid Fontana-Masson Staining
Rapid Fontana-Masson Staining
Duolink® References
Find Duolink references based on the type of method used, post translational modification detected, and research focus.
Genomics
Genomics protocols, reagents, and technical resources for your gene expression & silencing, DNA & RNA purification, PCR, qPCR, cloning, and sequencing needs.
Next Gen Sequencing
Next-Generation Sequencing (NGS) reagents and resources for massively parallel sequencing applications.
Molecular Biology & Functional Genomics
Explore our gene editing & functional genomics, molecular biology, oligos & qPCR probes, and immunoassay reagents and resources to make your next discovery.
Cloning & Expression
Cloning, protein expression vectors and techniques for optimal gene cloning and protein expression systems.
Imprint ® DNA Modification Kit (MOD50) Protocol
The Imprint DNA Modification Kit provides the reagents needed for bisulfite conversion and post-modification clean-up of DNA samples in less than 2 hours.
CRISPR-based Gene Activation
Sigma has developed a gene activation system based on a fusion of dCas9 to the catalytic histone acetyltransferase (HAT) core domain of the human E1A-associated protein p300.
Roche® Life Science Products
Roche Life Science Products - As the exclusive distributor of Roche products and biochemical reagents, we are committed to enabling your next breakthrough by providing dependable reagents that can quickly deliver high-quality, reproducible results.

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.