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Maoqing Jiang et al.
Oncology letters, 14(6), 6715-6723 (2018-01-19)
The current study aimed to explore whether the efficiency of the standard International Prognostic Index (S-IPI), revised-IPI (R-IPI) and enhanced-IPI (NCCN-IPI) in evaluating the prognosis of patients with diffuse large B-cell lymphoma (DLBCL) may be improved by interim
Mehmet Bozkurt et al.
La Radiologia medica, 126(2), 323-333 (2020-07-01)
The aim of this study was to assess the early therapy response in patients with unresectable CCA who received Y-90 microsphere therapy for CCA and define the factors related to therapy response. Data of 19 patients [extrahepatic (n: 6) and
Hunbo Shim et al.
Clinical nuclear medicine, 40(5), 394-396 (2015-02-24)
We observed that the diaphragmatic motion causing the well-known, so-called banana artifact on PET/CT images may additionally cause decreased FDG activity involving 1 or 2 lower thoracic vertebrae. The aim of this study was (1) to formally evaluate if this
Cayleih E Robertson et al.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 191(3), 589-601 (2021-03-02)
Small, non-hibernating endotherms increase their thermogenic capacity to survive seasonal cold, through adult phenotypic flexibility. In mammals, this response is primarily driven by remodeling of brown adipose tissue (BAT), which matures postnatally in altricial species. In many regions, ambient temperatures
Jennifer L Whitwell et al.
Neurology, 92(7), e710-e722 (2019-01-13)
To compare [18F]AV-1451 uptake in the semantic variant of primary progressive aphasia (svPPA) to Alzheimer dementia, and determine whether increased uptake in svPPA is associated with the presence of β-amyloid (Aβ). Thirty-one participants with svPPA underwent MRI and Pittsburgh compound
Michael Peter Jones et al.
Radiation oncology (London, England), 14(1), 140-140 (2019-08-08)
To investigate the prognostic significance of positron emission tomography (PET) parameters from F-18 fluorodeoxyglucose (FDG) PET scans performed pre- and post- chemo-radiotherapy (CRT) for squamous cell carcinoma of the anal canal (AC). From January 2013 to January 2017, 19 patients
Mark Radlinski et al.
Journal of thoracic disease, 12(10), 5850-5856 (2020-11-20)
Initial staging of esophageal cancer relies on EUS in addition to FDG-PET/CT. It is our hypothesis that with the advancement of FDG-PET/CT staging, endoscopic ultrasound may not be required for initial staging in all cases. The purpose of this study
Toru Sasaki et al.
Scientific reports, 9(1), 10685-10685 (2019-07-25)
Quality control of tissues and organs for transplant is important to confirm their safety and effectiveness for regenerative medicine. However, quality evaluation is only carried out using a limited range of inspection criteria, because many of the available evaluation tests
Lebriz Uslu-Beşli et al.
Nuclear medicine communications, 38(11), 964-970 (2017-09-02)
Prediction and early diagnosis of orbitopathy is needed in patients with Graves' disease, especially when radioiodine therapy is planned. Positron emission tomography/computerized tomography (PET/CT) using flourine-18-fluorodeoxyglucose (FDG) is an effective imaging modality in detection of inflammation, however, its ability to
John Radford et al.
The New England journal of medicine, 372(17), 1598-1607 (2015-04-23)
It is unclear whether patients with early-stage Hodgkin's lymphoma and negative findings on positron-emission tomography (PET) after three cycles of chemotherapy with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) require radiotherapy. Patients with newly diagnosed stage IA or stage IIA Hodgkin's
Gabriel Morin et al.
European journal of internal medicine, 62, 67-71 (2019-02-04)
The aim of this study was to evaluate the prognostic value of persistent retroperitoneal fibrosis FDG uptake using FDG/PET CT in patients with idiopathic retroperitoneal fibrosis (IRF). In this monocentric retrospective cohort study, all patients admitted for IRF from January
Claes Nøhr Ladefoged et al.
Physics in medicine and biology, 66(5), 054003-054003 (2021-02-02)
Cardiac [18F]FDG-PET is widely used for viability testing in patients with chronic ischemic heart disease. Guidelines recommend injection of 200-350 MBq [18F]FDG, however, a reduction of radiation exposure has become increasingly important, but might come at the cost of reduced
Keine Nishiyama et al.
Lab on a chip, 19(2), 233-240 (2018-12-14)
We have developed a microdevice for therapeutic drug monitoring. In this device, dispensing of sample and reagent was accomplished by simple manual operation of a syringe. Moreover, for a simple and rapid measurement, we used cloned enzyme donor immunoassay as
Osamu Manabe et al.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 26(3), 909-918 (2017-12-16)
FDG PET/CT plays a significant role in the diagnosis of inflammatory heart diseases and cardiac tumors. We attempted to determine the optimal FDG uptake threshold for volume-based analyses and to evaluate the relationship between the myocardial physiological uptake volume in
Natsuki Yonezawa et al.
Nagoya journal of medical science, 79(2), 189-198 (2017-06-20)
The aim of this study was to investigate the prognostic value of dual-time-point (DTP)
Jeong Won Lee et al.
European radiology, 27(5), 1912-1921 (2016-09-04)
This study aimed to assess the relationship between bone marrow (BM) FDG uptake on PET/CT and serum inflammatory markers and to evaluate the prognostic value of BM FDG uptake for predicting clinical outcomes in non-small cell lung cancer (NSCLC) patients.
Serge A Mitelman et al.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 21(5), 368-382 (2019-09-26)
Objectives: Overlapping decreases in extrastriatal dopamine D2/D3-receptor availability and glucose metabolism have been reported in subjects with schizophrenia. It remains unknown whether these findings are physiologically related or coincidental.Methods: To ascertain this, we used two consecutive 18F-fluorodeoxyglucose and 18F-fallypride positron
C N Berger et al.
Cytometry, 17(3), 216-223 (1994-11-01)
The quantitation of intracellular beta-galactosidase activity has been described for viable cells. By using the fluorogenic substrate fluorescein-di-beta-D-galactopyranoside (FDG) in conjunction with flow cytometry, the proportion of positive cells as well as the level of expression can be determined. In
Sander C J Verfaillie et al.
European radiology, 25(10), 3050-3059 (2015-04-23)
Alzheimer's disease (AD) and frontotemporal (FTD) dementia can be differentiated using [(18)F]-2-deoxy-2-fluoro-D-glucose (FDG)-PET. Since cerebral blood flow (CBF) is related to glucose metabolism, our aim was to investigate the extent of overlap of abnormalities between AD and FTD. Normalized FDG-PET
Takao Ono et al.
The Analyst, 143(20), 4923-4929 (2018-09-18)
Single-molecule digital enzyme assay using micron-sized droplet array is a promising analysis method to quantify biomolecules at extremely low concentrations. However, multiplex digital enzyme assays are still difficult to access because the best buffer conditions can vary largely among enzymes.
Ole Steen Bjerring et al.
Endoscopy, 51(2), 165-168 (2018-07-24)
Modern cancer diagnostic work-up is based on multiple modalities within a short time period. The interplay between these modalities is complex and not well known. Performing biopsy procedures prior to (18)F-2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography/computed tomography (PET/CT) is considered to
Jung W Choi et al.
PloS one, 14(1), e0211012-e0211012 (2019-01-27)
99m-Technetium-labeled (99mTc) erythrocyte imaging with planar scintigraphy is widely used for evaluating both patients with occult gastrointestinal bleeding and patients at risk for chemotherapy-induced cardiotoxicity. While a number of alternative radionuclide-based blood pool imaging agents have been proposed, none have
Margarita Kirienko et al.
European journal of nuclear medicine and molecular imaging, 45(2), 207-217 (2017-09-26)
Radiomic features derived from the texture analysis of different imaging modalities e show promise in lesion characterisation, response prediction, and prognostication in lung cancer patients. The present study aimed to identify an images-based radiomic signature capable of predicting disease-free survival
Kazuhiro Kitajima et al.
European journal of nuclear medicine and molecular imaging, 42(9), 1371-1377 (2015-05-08)
To determine whether (18)F-FDG uptake in breast cancer correlates with immunohistochemically defined subtype and is able to predict molecular subtypes. This retrospective study involved 306 patients with 308 mass-type invasive breast cancers (mean size 2.65 cm, range 1.0-15.0 cm) who
Katja N De Paepe et al.
Journal of magnetic resonance imaging : JMRI, 48(4), 897-906 (2018-04-16)
Correct staging and treatment initiation in malignant lymphoma depends on accurate lymph node characterization. However, nodal assessment based on conventional and diffusion-weighted (DWI) MRI remains challenging, particularly in smaller nodes. To evaluate first-order apparent diffusion coefficient (ADC) texture parameters compared
Sungmin Jun et al.
Cancer imaging : the official publication of the International Cancer Imaging Society, 18(1), 35-35 (2018-09-28)
In a previous study, FDG PET tumor segmentation (SegPHL) using the peritumoral halo layer (PHL) was more reliable than fixed threshold methods in patients with thyroid cancer. We performed this study to validate the reliability and accuracy of the PHL
Jujuan Wang et al.
Journal of cancer research and clinical oncology, 142(4), 859-871 (2015-12-17)
The significance of positron emission tomography/computed tomography (PET-CT) in identifying patients with lymphoma-associated hemophagocytic lymphohistiocytosis (LAHLH) when pathological evidence is unavailable remains uncertain. In this retrospective study, 44 HLH patients who underwent PET-CT before clinical treatment were enrolled, and 18
Simona Kavaliauskiene et al.
Oncotarget, 7(48), 79885-79900 (2016-11-10)
2-fluoro-2-deoxy-D-glucose (FDG), labeled with 18F radioisotope, is the most common imaging agent used for positron emission tomography (PET) in oncology. However, little is known about the cellular effects of FDG. Another glucose analogue, 2-deoxy-D-glucose (2DG), has been shown to affect
Heerajnarain Bulluck et al.
Circulation. Cardiovascular imaging, 9(3), e003900-e003900 (2016-03-02)
Hybrid positron emission tomography and magnetic resonance allows the advantages of magnetic resonance in tissue characterizing the myocardium to be combined with the unique metabolic insights of positron emission tomography. We hypothesized that the area of reduced myocardial glucose uptake
Paul Flechsig et al.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 18(2), 243-248 (2015-09-04)
The demand to optimize multidisciplinary treatment strategies in patients with benign and malignant diseases of the lung and other organs has led to the increased need of mechanistic proof-of-concept studies in preclinical small animal models using new non-invasive imaging methods.
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