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Quantification of Infliximab in Human Serum by LC-MS/MS Using A Full-Length Stable Isotope Labeled Internal Standard
Infliximab, a chimeric monoclonal antibody, is used to treat rheumatoid arthritis, psoriatic arthritis, Crohn’s disease, and other autoimmune diseases.
Enzymatic Method for Determining Branched Chain Amino Acids (BCAA Assay)
Assay protocol for the colorimetric detection of Branched Chain Amino Acids (BCAA) in biological samples using the alanine assay kit.
Hopane Reference Standards for use as Petrochemical Biomarkers in Oil Field Remediation and Spill Analysis
We provide high-quality, relevant hopane reference standards to be used as biomarkers for petrochemical oil field remediation and spill analysis.
NMR Reference Standards
NMR reference standards ensure proper instrument performance. Review key operational parameters for these standards such as pw90, sensitivity, resolution and line shape.
Traceable Organic Certified Reference Materials for P-31 qNMR
The use of CRMs for the NMR quantification of phosphorylated organic compounds and metabolites offers several advantages as it is based on a signal comparison of the analyte with an internal or external reference standard.
Cannabinoid Certified Reference Materials (CRMs) for an Improved Testing Accuracy and Traceability
We offer a portfolio of cannabinoid CRMs such as THC and THCA, available as single component solutions or mixes, certified in accordance with ISO 17034 and ISO/IEC 17025 for accurate cannabinoid profiling and potency testing.
Melamine Analysis via GC-MS
Sigma-Aldrich presents an article about the analysis of melamine and related compounds in dog food with the use of more economical gas chromatography-mass spectrometry (GC-MS) instrumentation.
Analysis of Tetrahydrocannabinol (THC) and Carboxytetrahydrocannabinol (THCCOOH) in Surface Waters by SPME and GC/MS
Analysis of Tetrahydrocannabinol (THC) and Carboxytetrahydrocannabinol (THCCOOH) in Surface Waters by SPME and GC/MS
SPME in the Analysis of Illicit Drugs
SPME is used in the analysis of amphetamine compounds by doing pre-extraction derivatization, and is also used in general determinations of other drugs of abuse.
GC Analysis of a 37-Component FAME Mix on Omegawax®
This technical article will discuss GC Analysis of a 37-Component FAME Mix on Omegawax.
Calculating Your Working Tolerance: A Guideline
Guideline to calculate your working tolerance - Certified Standard Solutions (CRM)
Improving the Chromatographic Separation of DMB-Labeled Sialic Acids for the Comparison of Biosimilars to Reference Materials
A significantly improved HPLC-fluorescence method for DMB-NANA and -NGNA, and application of this method to compare 2 candidate biosimilar therapeutic proteins to their respective RMs.
Solution with 17 Amino Acids as TraceCERT® Certified Reference Material
Technical article on "Solution with 17 Amino Acids as TraceCERT® Certified Reference Material"
Extractables Studies of Single-Use Equipment Immediate Identification and Quantification of Unknown Extractables by GC/MS with a Certified Reference Material Mix for Extractables and Leachables
Identification and quantification of the most common extractables originating from single-use equipment by GC/MS and an Extractables and Leachables Screening Standard.
Importance of Volumetric Solution Standardization
The titer determination or standardization of a titration solution is essential for accurate and reliable titration results.
Analysis of Pesticides in Baby Food by Solid Phase Microextraction (SPME) Using a New Overcoated Fiber
A direct immersion SPME method using a new overcoated SPME fiber was developed for the extraction of pesticides from pureed prune baby food.
Analysis of California Cannabis List of Pesticides, Mycotoxins, and Pyrethrins Using Ascentis® Express Biphenyl Column
Cannabis testing regulations include analysis of purity, potency, and contaminants. Learn more about analysis of cannabis for pesticides, mycotoxins, and pyrethrins registered in California by LC-MS/MS and GC-MS/MS Using Ascentis® Express Biphenyl and SLB®-5ms Columns
Vitamin D epi-Metabolites Separated with HybridSPE-Phospholipid
This Sigma-Aldrich article continues to detail new methodology for the analysis of Vitamin D metabolites using HybridSPE-Phospholipid technology.
New Certified Reference Materials for Proteins
CRMs of milk proteins aid accurate testing for infant formula, ensuring compliance and quality control.
Improving USP Lansoprazole Analysis with HPLC
USP methods continuously revised for modernization and improved results in drug testing.
Drinking Water Testing by Ion Chromatography using Ultrapure Water
This study reviews the suitability of ultrapure water for the IC analysis of drinking water. Inorganic ions and disinfectant by-products (DBPs) were assessed.
LC-MS Analysis of Warfarin™ in Plasma Samples
LC-MS analysis of Warfarin demonstrates its potential in clinical laboratories for accurate plasma measurements.
Analysis of Fats in Food & Beverages
This article explores the analysis of fats in food and beverage products. From derivatization of fatty acids to FAMEs, to analysis of FAME isomers, and more we are your one-stop shop for all of your food and beverage analysis needs.
New cis/trans FAME Standard for GC Optimization
AOCS and AOAC methods for trans fatty acid composition require highly polar cyanosilicone capillary columns.
Choosing Correct Reference Material Quality Grade
Choose ideal reference materials for analytical testing needs, whether for calibration or quantitative analysis, ensuring accuracy and reliability.
Radiello Sampler: Monitoring 1,3-Butadiene & Isoprene
Microbial test method development: Laboratory develops compliant methods for antimicrobial products, ensuring regulatory compliance and quality.
An LC/MS Peptide Standard for Rapid System Suitability Assessment and Retention Time Translation Across LC/MS Platforms
Standards are critical in liquid chromatography/mass spectrometry (LC/MS) based proteomics to ensure optimal and consistent system performance before, during, and after sample analysis.
High-Performance Thin-Layer Chromatography: A Fast and Efficient Fingerprint Analysis Method for Medicinal Plants
In this article we present several HPTLC applications and analytical standards for ginsenosides.
Determination of Stevioside and Rebaudioside A in Stevia leaves, beverages and food additives using HPTLC-MS
HPTLC-MS was used to analyze stevioside and rebaudioside in artificial sweeteners, stevia plants, cola and isotonic drinks with a minimum of sample preparation.
Isotopic Labeling for NMR Spectroscopy of Biological Solids
Isotopic Labeling for NMR Spectroscopy of Biological Solids;
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