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Cell signaling

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Although actin is one of the most conserved eukaryotic proteins, it is expressed as six isoforms characterized by electrophoresis and amino acid sequence analysis. Four of the six isoforms represent differentiation markers of muscle tissues. The other two are found
Nanodisc Technology: A Revolutionary System for Study of Membrane Proteins
Read our article about how the Nanodisc system allows for structural studies of membrane proteins.
Interleukin Family (IL)
The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and
Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds
Cholesterol Biosynthesis Regulation
The amount of cholesterol that is synthesized in the liver is tightly regulated by dietary cholesterol levels. LDL receptors regulate the cellular transport of lipid rich low density lipoprotein (LDL) particles.
Vimentin is an intermediate filamentous cytosketetal protein found in cells of mesenchymal origin. Vimentin typically exists as a coiled-coil dimer that interacts with another dimers to form a tetrameric complex that forms cytoskeletal protein sheets
Vascular Endothelial Growth Factors (VEGF)
Vascular endothelial growth factor (VEGF) is a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGF-A (VEGF) is a potent growth factor for blood vessel endothelial cells, showing pleiotropic
Sensor Dyes
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
Melatonin Receptors
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Myelin Associated Glycoprotein (MAG)
Myelin Associated Glycoprotein (MAG) is a type I transmembrane glycoprotein containing five Ig-like domains in its extracellular domain. It is an adhesion molecule belonging to the immunoglobin superfamily.
Insulin-like Growth Factors (IGF)
Insulin-like Growth Factors (IGF)
O-Linked Glycan Strategies
Learn about O-linked glycan strategies, such as the actions of O-glycosidase, how to remove di and trisialylation sialic acid residues, β-linked galactose, and N-acetylglucosamine, as well as other O-glycan modifications.
Peptidoglycan Structure, Biosynthesis and Function
The basic structure of peptidoglycan (PGN) contains a carbohydrate backbone of alternating units of N-acetylglucosamine (GlcNAc) and Nacetylmuramic acid, with the N-acetylmuramic acid residues cross-linked to peptides.
The AMP-activated protein kinase (AMPK) acts as a sensor of cellular energy status. AMPK exists as heterotrimeric complexes comprising a catalytic α subunit and regulatory β and γ subunits.
We offers many products related to neuropeptidases for your research needs.
Mitogen-activated Protein Kinases (MAPKs)
The mitogen-activated protein kinase (MAPK) family consists of stress-activated (SAPK) and MAPKs. Learn about their network of signal transduction cascades that mediate cellular responses to a diverse range of stimuli.
Caspases Inhibitors and Activators
Agents reported to activate cellular caspases include chemotherapeutic drugs, TNF receptor agonists, and other enzymes. Inhibitors of apoptosis were the first identified endogenous caspase inhibitors.
Nitric Oxide Synthases
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Phosphoprotein Phosphatases (Serine/Threonine)
We offers many products related to phosphoprotein phosphatases (Serine/Threonine) for your research needs.
Galanin Receptors
We offer many products related to galanin receptors for your research needs.
Phospholipase A2
Phospholipase A2 (PLA2) designates a class of enzymes that hydrolyze the sn-2 ester of glycerophospholipids to produce a fatty acid and a lysophospholipid. It has become clear that some of these enzymes liberate arachidonic acid in mammalian cells for the
Angiotensin Receptors
We offer many products related to angiotensin receptors for your research needs.
Phospholipase C
The hydrolysis of a minor membrane phospholipid, phosphatidylinositol 4,5-bisphosphate (PIP2) by a specific phospholipase C (PLC) is one of the earliest key events in the regulation of various cell functions by more than 100 extracellular signaling molecules.
Transient Receptor Potential Channels
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Sodium Channels
Voltage-gated sodium channels are present in most excitable cell membranes and play an important role in generating action potentials.
Tec Kinases
Tec kinases are activated in response to cellular stimulation by antigen receptors, integrins, growth factors, cytokines, and G protein-coupled receptors.
Focal Adhesion Kinase (FAK) Overview
The focal adhesion kinase (FAK) is a cytoplasmic protein tyrosine kinase. FAK has been implicated as a downstream signaling molecule that functions in the control of several integrin-regulated biological processes.
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