MilliporeSigma
Search Within
Applications
Content Type

Mass spectrometry

Applied Filters:
facet applications:Mass spectrometry
facet content type:Technical Article
Quantification of Infliximab in Human Serum by LC-MS/MS Using A Full-Length Stable Isotope Labeled Internal Standard
Infliximab, a chimeric monoclonal antibody, is used to treat rheumatoid arthritis, psoriatic arthritis, Crohn’s disease, and other autoimmune diseases.
Hopane Reference Standards for use as Petrochemical Biomarkers in Oil Field Remediation and Spill Analysis
We provide high-quality, relevant hopane reference standards to be used as biomarkers for petrochemical oil field remediation and spill analysis.
The Derivatization and Analysis of Amino Acids by GC-MS
The Derivatization and Analysis of Amino Acids by GC-MS
Melamine Analysis via GC-MS
Sigma-Aldrich presents an article about the analysis of melamine and related compounds in dog food with the use of more economical gas chromatography-mass spectrometry (GC-MS) instrumentation.
Exactly Why is Low Bleed Important for Capillary Columns?
Exactly Why is Low Bleed Important for Capillary Columns?
Analysis of Remdesivir and other Antiviral Drugs Using LC-MS/MS
We present a fast and robust HPLC-MS/MS method that can be used for Remdesivir and three structural antiviral analogues
Supel™-Select Polymeric SPE
Supel-Select HLB SPE - a hydrophilic modified styrene based polymer developed for the solid phase extraction of a broad range of compounds from aqueous samples.
Ion-Suppression & Phospholipid Contamination
We are presenting an article focusing on ion-suppression and phospholipid contamination and some of their major causes and difficulties.
Rapid Determination of Protein Binding Affinity Using Solid Phase Microextraction
Accurate protein binding affinities were measured using bioSPME more rapidly than membrane dialysis (RED) techniques. Binding affinities correlated to the reference values.
Analysis of Tetrahydrocannabinol (THC) and Carboxytetrahydrocannabinol (THCCOOH) in Surface Waters by SPME and GC/MS
Analysis of Tetrahydrocannabinol (THC) and Carboxytetrahydrocannabinol (THCCOOH) in Surface Waters by SPME and GC/MS
Bioanalysis with SPME
Biocompatible SPME devices employ C18 bonded porous silica sorbent particles, in a binder which resists fouling by biological matrix components
SPME in the Analysis of Illicit Drugs
SPME is used in the analysis of amphetamine compounds by doing pre-extraction derivatization, and is also used in general determinations of other drugs of abuse.
Ultra-Pure MALDI Matrices
One of the most important aspects of our ultra-pure MALDI matrix substances is their ability to dissolve rapidly and completely; a brief vortex mixing is typically sufficient.
Optimising the LC-MS Analysis of Biomolecules
We present an article concerning optimising the LC-MS analysis of biomolecules.
HybridSPE-Phospholipid Technology
This Sigma-Aldrich article discusses how the HybridSPE-Phospholipid Technology works and how the phospholipids are removed.
Evaluation of Different Enzymes on Hydrolysis Efficiencies of Glucuronide Drug Metabolites in Urine
β-glucuronidase (GUS) enzymes are utilized to hydrolyze glucuronide (gluc) drug metabolites to the parent drug, facilitating analysis by LC-MS/MS.
Validation of RNAi Knockdown Using Multiple Reaction Monitoring and Protein-AQUA
The field of proteomics is continually looking for new ways to investigate protein dynamics within complex biological samples. Recently, many researchers have begun to use RNA interference (RNAi) as a method of manipulating protein levels within their samples, but the
Ultrapure Water to Assess Elemental Impurities per USP
Elemental impurities in pharmaceutical drugs present a risk to human health and are regulated. Milli-Q® ultrapure water purification systems comply with the requirements for trace element analyses.
HybridSPE®-Phospholipid Technology
Innovative solid phase extraction (SPE) technology from Supelco, utilizes phospholipid retention mechanism based on highly selective interaction between proprietary zirconia ions (bonded to the stationary phase) and the phosphate moiety consistent with phospholipids and proteins.
Analysis of Pesticides in Baby Food by Solid Phase Microextraction (SPME) Using a New Overcoated Fiber
A direct immersion SPME method using a new overcoated SPME fiber was developed for the extraction of pesticides from pureed prune baby food.
Analysis of California Cannabis List of Pesticides, Mycotoxins, and Pyrethrins Using Ascentis® Express Biphenyl Column
Cannabis testing regulations include analysis of purity, potency, and contaminants. Learn more about analysis of cannabis for pesticides, mycotoxins, and pyrethrins registered in California by LC-MS/MS and GC-MS/MS Using Ascentis® Express Biphenyl and SLB®-5ms Columns
Vitamin D epi-Metabolites Separated with HybridSPE-Phospholipid
This Sigma-Aldrich article continues to detail new methodology for the analysis of Vitamin D metabolites using HybridSPE-Phospholipid technology.
Sample Cleanliness Using BioSPME
Learn about Supel™ BioSPME C18 96-pin tool to prepare a clean sample with minimal matrix effects for an LC-MS/MS analysis from human plasma and its comparison with acetonitrile-based precipitation.
BioSPME for Plasma Protein Binding Assay: Details of Method Development and Optimization
Determination of plasma protein binding using a SupelTM C18 pin device based BioSPME method for efficient sample preparation, along with a comparison to the equilibrium dialysis method.
New Certified Reference Materials for Proteins
CRMs of milk proteins aid accurate testing for infant formula, ensuring compliance and quality control.
LC-MS Analysis of Warfarin™ in Plasma Samples
LC-MS analysis of Warfarin demonstrates its potential in clinical laboratories for accurate plasma measurements.
Effect of Container Materials on Milk Off-Flavors
HS-SPME with Carboxen®/PDMS coated Nitinol fiber allows low MW analyte detection in light-exposed milk plastics.
Absolute Quantification of Serum Proteome
Protein-AQUA™™ offers robust targeted proteomics for quantitative studies across diverse research areas.
An LC/MS Peptide Standard for Rapid System Suitability Assessment and Retention Time Translation Across LC/MS Platforms
Standards are critical in liquid chromatography/mass spectrometry (LC/MS) based proteomics to ensure optimal and consistent system performance before, during, and after sample analysis.
GC/MS/MS Analysis of BPA in Energy Drink
Study demonstrates SPME of BPA from an energy drink using an overcoated PDMS/DVB fiber, followed by GC/MS/MS analysis.
Page 1 of 3