MilliporeSigma
Search Within
Applications
Content Type
Collections

Protein expression

Applied Filters:
facet applications:Protein expression
facet content type:Technical Article
Phase I Drug Metabolism
Phase I biotransformation reactions introduce or expose functional groups on the drug with the goal of increasing the polarity of the compound. Although Phase I drug metabolism occurs in most tissues, the primary and first pass site of metabolism occurs
ATP Synthase
Learn about ATP synthase with our molecular machine video animation showing this mechanism that provides energy to cells. Our animation is provided in partnership with Dr Nicholson and the IUBMB.
An ECM Mimetic Library for Engineering Surfaces to Direct Cell Surface Receptor Binding Specificity and Signaling
The extracellular (ECM) microenvironment, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions. For this reason, engineering the ECM microenvironment provides
MISSION shRNA Lentiviral Transduction
MISSION® shRNA Lentiviral Transduction application data
Cytokine Receptors (Hematopoetin Receptor Family)
We offer many products related to Cytokine Receptors (Hematopoetin Receptor Family) for your research needs.
Sensor Dyes
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
NF-κB and Inflammation
Chronic inflammation is an underlying factor in the development and progression of many of the chronic diseases of aging, such as arthritis, atherosclerosis, diabetes, and cancer.
Nuclear Receptors (Non-Steroids)
We offer many products related to non-steroid nuclear receptors for your research needs.
Lipid-induced Insulin Resistance
Lipid Induced Insulin Resistance
Sigma Receptors
Sigma receptors may constitute favorable targets for drug design in conditions such as psychiatric and movement disorders, amnesia, depression, cancer, inflammation and cocaine addiction.
Cell Lines for Recombinant Protein Expression
Eukaryotic cell lines aid in complex post-translational modifications and folding of recombinant proteins. Find suitable recombinant protein production cell lines.
GABA Transporters
Sigma-Aldrich offers many products related to GABA transporters for your research needs.
Melatonin Receptors
We offer many products related to melatonin receptors for your research needs.
Glutamate Receptors (G Protein Family)
Sigma-Aldrich offers many products related to G-protein family glutamate receptors for your research needs.
Duolink® Proximity Ligation Assay Instructional Video
This video will show you step-by-step how to perform a Duolink® PLA experiment with cells on a slide that have already been fixed and permeabilized by the user.
Detection of Protein-protein Interactions by in situ PLA
Proteins are complex biological molecules essential for cellular structure and functions. The majority of proteins commonly interact with various molecules, including other proteins, in order to exert their functions.
Duolink® Proximity Ligation Assay (PLA) Multicolor Kits for Sensitive Multiplex Detection
Duolink® PLA Multicolor technology and the quantification of protein-protein interactions in fixed tissues and cells.
Histamine Synthesis and Metabolism
Our company offers many products related to histamine synthesis and metabolism for your research needs.
GABAA Receptors
We offer many products related to GABAA receptors for your research needs.
Troubleshooting in pGEX Expression Vectors
This page describes troubleshooting strategies for cloning the gene or gene fragment into a pGEX expression vector.
Directed Evolution
An overview of directed evolution and the methods for generating proteins with optimized or entirely new functions.
Leukotriene Receptors
Sigma-Aldrich offers many products related to leukotriene receptors for your research needs.
How to Optimize Duolink® PLA for Flow Cytometry Detection
Considerations for proper experimental design, preparation and execution of the Duolink® PLA for flow cytometry protocol.
Tag Removal Proteases for Recombinant Protein Purification
Proteases for biotinylated tag removal for protein purification workflows with related reagents and technical resources.
Duolink® PLA Troubleshooting Guide
Support information including tips and tricks, frequently asked questions, and basic troubleshooting.
How to Optimize the Duolink® Proximity Ligation Assay
Things to consider for preparation, setup and execution of the Duolink® assay protocol
Studies of Dimerization and Activation of Receptors in the EGFR-Family Using Duolink® Assays
Our aim was to investigate the dimerization and activation pattern of two receptors, EGFR (ErbB1) and HER2 (ErbB2), in the EGFR-family using breast cancer cell lines and selected colon tissues as model systems.
Canonical Wnt / β-Catenin Signaling
We review the Wnt signaling pathway (also, canonical Wnt or beta (β)-catenin pathway) and provide links to related products at sigmaaldrich.com.
EGFR
Our company offers many products related to EGFR for your research needs.
Serotonin Synthesis and Metabolism
Serotonin (5-hydroxytryptamine) is principally found stored in three main cell types - i) serotonergic neurons in the CNS and in the intestinal myenteric plexus, ii) enterochromaffin cells in the mucosa of the gastrointestinal tract, and iii) in blood platelets. Metabolism
Page 1 of 4
Page 1 of 4