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" within Papers

Anti-tumour activity of Digitalis purpurea L. subsp. heywoodii.

Miguel López-Lázaro et al.

Planta medica, 69(8), 701-704 (2003-10-08)

Recent research has shown the anticancer effects of digitalis compounds suggesting their possible use in medical oncology. Four extracts obtained from the leaves of Digitalis purpurea subsp. heywoodii have been assessed for cytotoxic activity against three human cancer cell lines

Analysis of sterol and other components present in unsaponifiable matters of mahua, sal and mango kernel oil.

Rupali Dhara et al.

Journal of oleo science, 59(4), 169-176 (2010-03-20)

The amount and characterization of phytosterol and other minor components present in three Indian minor seed oils, mahua (Madhuca latifolia), sal (Shorea robusta) and mango kernel (Mangifera indica), have been done. Theses oils have shown commercial importance as cocoa-butter substitutes

Simultaneous determination of cardenolides by sonic spray ionization liquid chromatography-ion trap mass spectrometry--a fatal case of oleander poisoning.

Tomonori Arao et al.

Journal of analytical toxicology, 26(4), 222-227 (2002-06-11)

Simultaneous determination of oleandrin and its three related compounds, desacetyloleandrin, oleandrigenin, and gitoxigenin in blood by using liquid chromatography-three-dimensional quadrupole mass spectrometry (LC-3DQMS) system equipped with sonic spray ionization (SSI) interface was conducted. This analyzing method was suitable for all

Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients.

Miguel López-Lázaro et al.

Journal of natural products, 68(11), 1642-1645 (2005-11-29)

The cardiac glycosides digitoxin (1) and digoxin (3) have been used in cardiac diseases for many years. During this time several reports have suggested the possible use of digitalis in medical oncology. Several analogues of digitoxin (1) were evaluated for

The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen.

Jack T Rogers et al.

Journal of neural transmission (Vienna, Austria : 1996), 118(3), 493-507 (2011-01-12)

Increased brain α-synuclein (SNCA) protein expression resulting from gene duplication and triplication can cause a familial form of Parkinson's disease (PD). Dopaminergic neurons exhibit elevated iron levels that can accelerate toxic SNCA fibril formation. Examinations of human post mortem brain

Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs.

Jenny Felth et al.

Journal of natural products, 72(11), 1969-1974 (2009-11-10)

Cardiac glycosides have been reported to exhibit cytotoxic activity against several different cancer types, but studies against colorectal cancer are lacking. In a screening procedure aimed at identifying natural products with activity against colon cancer, several cardiac glycosides were shown

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