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Ashfaq Ahmad et al.
Drug design, development and therapy, 14, 2165-2178 (2020-07-02)
The current study was designed to synthesize derivatives of succinimide and compare their biological potency in anticholinesterase, alpha-glucosidase inhibition, and antioxidant assays. In this research, two succinimide derivatives including (S)-1-(2,5-dioxo-1-phenylpyrrolidin-3-yl) cyclohexanecarbaldehyde (Compound 1) and (R)-2-((S)-2,5-dioxo-1-phenylpyrrolidin-3-yl)-2-phenylpropanal (Compound 2) were synthesized using
Alessio Innocenti et al.
Bioorganic & medicinal chemistry, 18(6), 2159-2164 (2010-02-27)
A series of phenolic acids and phenol natural products, such as p-hydroxybenzoic acid, p-coumaric acid, caffeic acid, ferulic acid, gallic acid, syringic acid, quercetin, and ellagic acid, were investigated for their inhibitory effects against the metalloenzyme carbonic anhydrase (CA, EC
Hugo Pereira et al.
Marine drugs, 13(6), 3531-3549 (2015-06-06)
Four lipid-rich microalgal species from the Red Sea belonging to three different genera (Nannochloris, Picochlorum and Desmochloris), previously isolated as novel biodiesel feedstocks, were bioprospected for high-value, bioactive molecules. Methanol extracts were thus prepared from freeze-dried biomass and screened for
Li-Wen Tian et al.
Journal of natural products, 73(2), 160-163 (2010-01-23)
Five new phloroglucinol glycosides, eucalmainosides A-E (1-5), were isolated from the fresh fruits of Eucalyptus maideni, along with 15 flavonoids (6-20), seven (+)-oleuropeic acid derivatives (15, 16, and 22-26), three hydrolyzable tannins (32-34), and six simple phenolic compounds (21, 27-31).
Chamira Dilanka Fernando et al.
Nutrition journal, 14, 74-74 (2015-08-01)
Tea is the most consumed beverage in the world which is second only to water. Tea contains a broad spectrum of active ingredients which are responsible for its health benefits. The composition of constituents extracted to the tea brew depends
Chuan-Chung Tsao et al.
Bioorganic & medicinal chemistry, 16(22), 9867-9870 (2008-10-18)
A phytochemical investigation of the leaves of Erythrophleum fordii Oliv. has led to the isolation of three new cassaine-type diterpenoids, erythrofordin A (1), erythrofordin B (2) and erythrofordin C (3), as well as a norcassaine diterpenoid with a novel skeleton
Dima Mnayer et al.
Molecules (Basel, Switzerland), 19(12), 20034-20053 (2014-12-04)
Six essential oils (EOs) from the Alliaceae family, namely garlic (Allium sativum), onion (Allium cepa), leek (Allium porrum), Chinese chive (Allium tuberosum), shallot (Allium ascalonicum) and chive (Allium schoenoprasum) were characterized by GC and GC-MS and evaluated for their functional
Wan-Su Kim et al.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 19(1), 21-27 (2015-01-22)
The anti-inflammatory, antioxidant, and antimicrobial properties of artemisinin derived from water, methanol, ethanol, or acetone extracts of Artemisia annua L. were evaluated. All 4 artemisinin-containing extracts had anti-inflammatory effects. Of these, the acetone extract had the greatest inhibitory effect on
Janique Vandal et al.
Pharmaceutical biology, 53(6), 800-806 (2015-02-24)
The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only a few antimicrobial agents left that can be used against MDR
Claudia Scattino et al.
Food chemistry, 163, 51-60 (2014-06-11)
In the present study the possibility of enhancing phenolic compound contents in peaches and nectarines by post-harvest irradiation with UV-B was assessed. Fruits of 'Suncrest' and 'Babygold 7' peach and 'Big Top' nectarine cultivars were irradiated with UV-B for 12
José Agustín Tapia-Hernández et al.
Journal of food science, 84(4), 818-831 (2019-02-26)
Currently, electrospraying is a novel process for obtaining the nanoparticles from biopolymers. Zein nanoparticles have been obtained by this method and used to protect both hydrophilic and hydrophobic antioxidant molecules from environmental factors. The objective of this work was to
Mst Shahnaj Parvin et al.
BMC research notes, 8, 412-412 (2015-09-06)
The various parts of Cresecentia cujete have some important biological activities. In folklore medicine leaves are used to treat hematomas, tumors and hypertension. Fruit decoction is used to treat diarrhea, stomachaches, cold, bronchitis, cough, asthma, and urethritis. The present study
Elizabeth M O Yeboah et al.
Journal of natural products, 73(6), 1151-1155 (2010-05-27)
Three new dihydro-beta-agarofuran polyesters, 1alpha,9beta-difuranoyloxy-2-oxodihydro-beta-agarofuran (1), 1alpha,9beta-difuranoyloxy-2-oxo-3-enedihydro-beta-agarofuran (2), and 1alpha,9beta-difuranoyloxydihydro-beta-agarofuran (3), have been isolated from the CHCl(3) extract of the root bark of Osyris lanceolata, together with two known pentacylic triterpenoids, 4 and 5. Compounds 1-5 did not scavenge the
Elisabeth M Gross et al.
Journal of insect physiology, 54(2), 462-471 (2008-01-04)
Larvae of the freshwater moth Acentria ephemerella (Pyralidae, Lepidoptera) can fully develop on Myriophyllum spicatum, a submerged macrophyte containing 7-10% of its dry mass as tannins. We investigated the physicochemical gut parameters of larvae fed with M. spicatum or Potamogeton
Marija Karapandzova et al.
Natural product communications, 10(6), 987-990 (2015-07-23)
Flavonoids and other phenolic compounds in young needles of four pine species, Pinus peuce, P. nigra, P. mugo and P. sylvestris from the Macedonian flora were investigated. The amount of total phenols and total flavonoids were determined using Folin-Ciocalteau and
Aliya Ahmad et al.
Pharmaceutical biology, 53(5), 758-766 (2015-03-11)
Soybean and its fermented products are the most common source of isoflavones in human food. The present study quantifies the major glycosides and aglycones in soybean and its fermented product tempeh isoflavone extracts. The comparision of antioxidant effects and BACE1
Dolores González de Llano et al.
International journal of molecular sciences, 16(6), 12119-12130 (2015-05-30)
Cranberry consumption has shown prophylactic effects against urinary tract infections (UTI), although the mechanisms involved are not completely understood. In this paper, cranberry phenolic compounds and their potential microbial-derived metabolites (such as simple phenols and benzoic, phenylacetic and phenylpropionic acids)
Tamara Sotelo et al.
PloS one, 9(9), e107290-e107290 (2014-09-10)
Brassica vegetables possess high levels of antioxidant metabolites associated with beneficial health effects including vitamins, carotenoids, anthocyanins, soluble sugars and phenolics. Until now, no reports have been documented on the genetic basis of the antioxidant activity (AA) in Brassicas and
Jakub P Piwowarski et al.
Journal of natural medicines, 69(1), 100-110 (2014-10-29)
The herb Lythrum salicaria L. (Lythraceae) is used in traditional medicine to treat diseases with an inflammatory background, such as haemorrhoidal disease, dysentery, chronic intestinal catarrh, eczema, varicose veins, periodontosis and gingivitis. Because these diseases are closely associated with an
Wan Mohd Nuzul Hakimi Wan Salleh et al.
Archives of pharmacal research, 38(4), 485-493 (2014-08-08)
The present study aimed to examine the chemical compositions of the essential oils of Beilschmiedia madang and their antioxidant, antibacterial, antifungal, anticholinesterase and anti-tyrosinase activities. The major constituents of the essential oils of leaf and bark of B. madang were
Sui-Ku Liu et al.
Journal of Asian natural products research, 15(12), 1243-1248 (2013-11-05)
Two new glycosides, syringic acid-4-O-β-L-arabinopyranoside and kaempferol-3-O-α-L-rhamnopyranosyl-7-O-β-D-glucuronopyranoside, were isolated from whole plants of Carduus acanthoides (Asteraceae), and their structures were elucidated on the basis of spectroscopic analysis.
Anete Boroduske et al.
Industrial crops and products, 165, 113438-113438 (2021-03-24)
Berries and flowers of Sambucus nigra L. tree are well known for their ability to mitigate symptoms of upper respiratory disorders related to reported antiviral properties. Industrial application and commercial cultivation of S. nigra is largely limited to a few
Nicole Schöbel et al.
Chemical senses, 39(6), 471-487 (2014-04-11)
Astringency is an everyday sensory experience best described as a dry mouthfeel typically elicited by phenol-rich alimentary products like tea and wine. The neural correlates and cellular mechanisms of astringency perception are still not well understood. We explored taste and
Tatiana G Ribeiro et al.
Journal of ethnopharmacology, 165, 238-242 (2015-03-04)
Stryphnodendron obovatum Benth. is a Brazilian tree used to treat skin ulceration, promote wound healing, and inhibit the growth of protozoa, including Trypanosoma and Leishmania species. Bioguided fractionation of the ethanol extract of S. obovatum stem bark was performed, and
Carlos L Céspedes et al.
Environmental research, 132, 391-406 (2014-06-04)
The effects of persistent organic pollutants (POPs) on humans and biodiversity are multiple and varied. Nowadays environmentally-friendly pesticides are strongly preferred to POPs. It is noteworthy that the crop protection role of pesticides and other techniques, i.e. biopesticides, plant extracts
Xiao Ma et al.
Journal of medicinal food, 16(3), 259-262 (2013-02-27)
Skeletal muscle is a major organ that is important for whole-body glucose metabolism. We found that when isolated rat epitrochlearis muscle was incubated with a Pu-erh tea hot-water extract (PTE) for 30 min, the rate of 3-O-methyl-D-glucose (3MG) transport increased
Gokhan Bayramoglu et al.
Cytotechnology, 67(5), 845-849 (2014-05-09)
There is little information about the hepatoprotective effects of gallic acid against ischemia-reperfusion (I/R) damage. Animals were subjected to I/R. Gallic acid at doses of 50 and 100 mg/kg body weight (bw) were injected as a single dose prior to ischemia.
Jaekyun Choi et al.
eNeuro, 7(2) (2020-03-30)
Feeding, a critical behavior for survival, consists of a complex series of behavioral steps. In Drosophila larvae, the initial steps of feeding are food choice, during which the quality of a potential food source is judged, and ingestion, during which
Claudia Urueña et al.
Integrative cancer therapies, 14(5), 468-483 (2015-07-30)
Natural compounds are promising sources for anticancer therapies because of their multifunctional activity and low toxicity. Although the host immune response (IR) is clearly implicated in tumor control, the relationship between natural therapies and IR has not yet been elucidated.
Chloé Roullier-Gall et al.
PloS one, 9(5), e97615-e97615 (2014-05-27)
The chemical composition of grape berries is influenced by various environmental conditions often considered to be representative of a "terroir". If grapes from a given terroir are assumed to reflect this origin in their chemical compositions, the corresponding wine should
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