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John P H Wilding
Metabolism: clinical and experimental, 63(10), 1228-1237 (2014-08-12)
The kidneys play an important role in regulating glucose homeostasis through utilization of glucose, gluconeogenesis, and glucose reabsorption via sodium glucose co-transporters (SGLTs) and glucose transporters. The renal threshold for glucose excretion (RTG) is increased in patients with type 2
Liwei Zhang et al.
Environmental technology, 35(9-12), 1064-1076 (2014-04-08)
The purpose of this study was to develop a mathematical model that can describe glucose degradation in a microbial fuel cell (MFC) with the use of finite difference approach. The dynamic model can describe both substrate and pH changes in
Christel Thauvin-Robinet et al.
American journal of human genetics, 93(1), 141-149 (2013-07-03)
Short stature, hyperextensibility of joints and/or inguinal hernia, ocular depression, Rieger anomaly, and teething delay (SHORT) syndrome is a developmental disorder with an unknown genetic cause and hallmarks that include insulin resistance and lack of subcutaneous fat. We ascertained two
Danuta Jarocha et al.
Cell transplantation, 24(4), 661-672 (2015-03-26)
Interruption of spinal cord (SC) continuity leads to functional loss below the lesion level. The purpose of this study was to evaluate the safety and efficacy of bone marrow nucleated cell (BMNC) and multiple mesenchymal stem cell (MSC) transplantations in
Samudra Sengupta et al.
Nature chemistry, 6(5), 415-422 (2014-04-24)
Non-mechanical nano- and microscale pumps that function without the aid of an external power source and provide precise control over the flow rate in response to specific signals are needed for the development of new autonomous nano- and microscale systems.
Tomohisa Mori et al.
Journal of pharmacological sciences, 126(1), 47-55 (2014-08-22)
The rewarding effects of μ-receptor agonists can be suppressed under several pain conditions. We recently showed that clinically used μ-receptor agonists possess efficacies for relieving the neuropathic pain induced by chemotherapeutic drug in rats; however, it is possible that the
O I Kliaĭn et al.
Prikladnaia biokhimiia i mikrobiologiia, 49(3), 292-300 (2013-07-26)
The ability of the white rot basidiomycetes Trametes hirsuta and Trametes maxima to transform coal humic substances (HS's) under the conditions of solid phase cultivation in the presence or absence of an easily available source of corbon (glucose) has been
E A Tigunova et al.
TSitologiia i genetika, 47(6), 51-71 (2014-01-21)
Butanol--an alternative fuel that on amid dwindling global (accessible) oil reserves can serve as a source of energy. In the industrial-scale butanol is produced by chemical synthesis, although initially butanol production was due to microbiological synthesis. For cost-efficient production, a
Wan-Chun Lai et al.
Journal of natural products, 77(7), 1624-1631 (2014-07-16)
Cirsium japonicum var. australe, used as a folk medicine in Taiwan, has been employed traditionally in the treatment of diabetes and inflammatory symptoms. Bioactivity-guided fractionation of its ethanolic extract, utilizing centrifugal partition chromatography monitored by DPPH-TLC analysis, led to the
B M Rovenko et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 85(5), 61-72 (2014-02-01)
The influence of 20 and 1% glucose and fructose, which were components of larval diet, on the level of oxidized proteins and lipids, low molecular mass antioxidant content as well as activities of antioxidant and associated enzymes in adult fruit
Fozia Shaheen et al.
Biochimica et biophysica acta, 1842(9), 1762-1769 (2014-06-28)
Telomerase reverse transcriptase (TERT) is a key component of the telomerase complex. By lengthening telomeres in DNA strands, TERT increases senescent cell lifespan. Mice that lack TERT age much faster and exhibit age-related conditions such as osteoporosis, diabetes and neurodegeneration.
R G Browning et al.
Annals of emergency medicine, 19(6), 683-687 (1990-06-01)
The empiric administration of 50% dextrose to all patients presenting to the ED with altered mental status is a standard of care predicated on the assumption that glucose administration is harmless to non-hypoglycemic patients. Considerable evidence now disputes this assumption.
Katharina Timper et al.
Cell metabolism, 31(6), 1189-1205 (2020-05-21)
Astrocytes represent central regulators of brain glucose metabolism and neuronal function. They have recently been shown to adapt their function in response to alterations in nutritional state through responding to the energy state-sensing hormones leptin and insulin. Here, we demonstrate
Mesoamerica's mystery killer.
Jon Cohen
Science (New York, N.Y.), 344(6180), 143-147 (2014-04-12)
Rengasamy Palanivel et al.
Metabolism: clinical and experimental, 63(10), 1363-1373 (2014-08-12)
Adiponectin is known to confer its cardioprotective effects in obesity and type 2 diabetes, mainly by regulating glucose and fatty acid metabolism in cardiomyocytes. Dynamic actin cytoskeleton remodeling is involved in regulation of multiple biological functions, including glucose uptake. Here
Corinne C Ramaley et al.
International journal of pharmaceutical compounding, 17(5), 436-438 (2014-01-28)
The objective of this study was to determine the compatibility of amiodarone hydrochloride with vasopressin during simulated Y-site administration. Amiodarone hydrochloride is compatible with vasopressin under simulated-use conditions when administered according to the Advanced Cardiac Life Support Guidelines. A simulated-use
High glucose and low specific cell growth but not mild hypothermia improve specific r-protein productivity in chemostat culture of CHO cells
Vergara M, et al.
Testing, 13(8), e0202098-e0202098 (2018)
Jocelyn Campbell et al.
Ecology, 94(5), 1186-1195 (2013-07-19)
Foliose lichens with cyanobacterial bionts (bipartite and tripartite) form a distinct assemblage of epiphytes strongly associated with humid microclimatic conditions in inland British Columbia. Previous research showed that these cyano- and cephalolichen communities are disproportionately abundant and species-rich on conifer
Metabolic quirks yield tumour hope.
Heidi Ledford
Nature, 508(7495), 158-159 (2014-04-11)
Nayara Peixoto-Silva et al.
Life sciences, 95(1), 14-21 (2013-12-24)
Studies have demonstrated that early weaning can promote metabolic syndrome during adulthood and that obesity increases oxidative stress. Thus, we aimed to evaluate redox status in a pharmacological early weaning rodent model programmed for metabolic syndrome at adulthood. Lactating dams
M A Gales et al.
The Annals of pharmacotherapy, 29(5), 523-529 (1995-05-01)
To review the data examining the use of rapid infusion of amphotericin B in dextrose infusions. A MEDLINE search of the English-language literature and review of pertinent references' bibliographies was used to identify articles evaluating the effect of amphotericin B
Juan P Zúñiga-Hertz et al.
The Journal of endocrinology, 224(1), 75-84 (2014-12-03)
Results from previous investigations have indicated that glucose-stimulated insulin secretion (GSIS) is affected by changes in cholesterol and its intermediates, but the precise link between secretion and cholesterol has not been thoroughly investigated. In this study, we show the contribution
Jia Liu et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(12), 158511-158511 (2019-08-30)
Brown adipose tissue (BAT) is a potential target to treat cardiometabolic disorders because of its capacity to combust glucose and fatty acids for thermoregulation. Its cellular and molecular investigation in humans is hampered by the limited availability of cell material
M Thompson
Drug intelligence & clinical pharmacy, 19(2), 106-111 (1985-02-01)
A review of the literature on the effectiveness of essential amino acid and hypertonic dextrose in the nutritional management of patients with acute renal failure is evaluated critically. Earlier case reports and studies published indicated that the administration of these
Qinjie Weng et al.
Cell stem cell, 24(5), 707-723 (2019-04-16)
The identity and degree of heterogeneity of glial progenitors and their contributions to brain tumor malignancy remain elusive. By applying lineage-targeted single-cell transcriptomics, we uncover an unanticipated diversity of glial progenitor pools with unique molecular identities in developing brain. Our
Mitchell B Sally et al.
The journal of trauma and acute care surgery, 76(1), 62-68 (2013-12-26)
The appropriate level of glucose control in organ donors after neurologic determination of death (DNDD) remains uncertain. We hypothesized that a glucose target of 180 mg/dL would be appropriate for optimizing organ transplantation rates and outcomes. Demographic, critical care, organ
[Current topics of purification and composition of dialysis fluid].
Tadashi Tomo
Nihon Jinzo Gakkai shi, 55(4), 498-501 (2013-07-04)
Michael J Van Kanegan et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(3), 963-968 (2014-01-17)
We have previously shown that the botanical drug candidate PBI-05204, a supercritical CO2 extract of Nerium oleander, provides neuroprotection in both in vitro and in vivo brain slice-based models for focal ischemia (Dunn et al., 2011). Intriguingly, plasma levels of
L V Harmanchuk et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 59(2), 52-58 (2013-07-05)
The effect of mitokorrectine (complex native oligopeptides isolated from neonatal pig brain) on endothelial cells in culture was investigated. It was revealed that the drug concentration-dependently induces angiogenesis in vitro. Mitogen effect of Mitokorrectine was shown by MTT-test and routine
Laura C Tegtmeyer et al.
The New England journal of medicine, 370(6), 533-542 (2014-02-07)
Congenital disorders of glycosylation are genetic syndromes that result in impaired glycoprotein production. We evaluated patients who had a novel recessive disorder of glycosylation, with a range of clinical manifestations that included hepatopathy, bifid uvula, malignant hyperthermia, hypogonadotropic hypogonadism, growth
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