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Showing 1-15 of 15 results for "g9771" within Papers
Natalie A Dye et al.
eLife, 10 (2021-03-27)
Tissue organization is often characterized by specific patterns of cell morphology. How such patterns emerge in developing tissues is a fundamental open question. Here, we investigate the emergence of tissue-scale patterns of cell shape and mechanical tissue stress in the
Salvador Hernández-Martínez et al.
PloS one, 12(4), e0175759-e0175759 (2017-04-21)
Allatotropins (AT) are neuropeptides with pleotropic functions on a variety of insect tissues. They affect processes such as juvenile hormone biosynthesis, cardiac rhythm, oviduct and hindgut contractions, nutrient absorption and circadian cycle. The present work provides experimental evidence that AT
Megan Levis et al.
Biomicrofluidics, 13(2), 024111-024111 (2019-05-09)
Microfluidic devices provide a platform for analyzing both natural and synthetic multicellular systems. Currently, substantial capital investment and expertise are required for creating microfluidic devices using standard soft-lithography. These requirements present barriers to entry for many nontraditional users of microfluidics
Wenmei Wu et al.
Autophagy, 17(2), 512-528 (2020-02-06)
Histone deacetylases (HDACs) are important for global gene expression and contribute to numerous physiological events. Deacetylase Rpd3 in yeast and its conserved homolog HDAC1 in mammals oppositely regulate autophagy; however, how Rpd3/HDAC1 is regulated to mediate autophagy remains unclear. Here
Jules Lavalou et al.
Developmental cell, 56(11), 1574-1588 (2021-05-02)
Interfaces between cells with distinct genetic identities elicit signals to organize local cell behaviors driving tissue morphogenesis. The Drosophila embryonic axis extension requires planar polarized enrichment of myosin-II powering oriented cell intercalations. Myosin-II levels are quantitatively controlled by GPCR signaling
Natalie A Dye et al.
Development (Cambridge, England), 144(23), 4406-4421 (2017-10-19)
Quantitative analysis of the dynamic cellular mechanisms shaping the
Yichen Dai et al.
Insect biochemistry and molecular biology, 116, 103255-103255 (2019-10-28)
Vacuolar-type H + -adenosine triphosphatases (V-ATPases) are indispensable for lysosome acidification and participate in autophagic processes. The steroid hormone 20-hydroxyecdysone (20E) predominantly induces autophagy and regulates insect larval molting and metamorphosis; however, the specific mechanism of lysosome acidification regulation by 20E remains
Mauricio Rv Sant'anna et al.
Parasites & vectors, 2(1), 62-62 (2009-12-17)
Leishmania parasites must overcome several barriers to achieve transmission by their sand fly vectors. One of the earliest threats is exposure to enzymes during blood meal digestion. Trypsin-like enzymes appear to be detrimental to parasite survival during the very early
Dharsan K Soundarrajan et al.
PLoS computational biology, 17(11), e1009543-e1009543 (2021-11-02)
Information flow within and between cells depends significantly on calcium (Ca2+) signaling dynamics. However, the biophysical mechanisms that govern emergent patterns of Ca2+ signaling dynamics at the organ level remain elusive. Recent experimental studies in developing Drosophila wing imaginal discs
Zhenru Zhou et al.
Current biology : CB, 29(5), 856-864 (2019-02-26)
Formation of correctly shaped organs is vital for normal function. The Drosophila wing has an elongated shape, which has been attributed in part to a preferential orientation of mitotic spindles along the proximal-distal axis [1, 2]. Orientation of mitotic spindles
Wenmei Wu et al.
International journal of molecular sciences, 21(18) (2020-09-24)
Tip60, a key histone acetyltransferase of the MYST family and member of the nuclear multimeric protein complex (NuA4), regulates the activity and stability of proteins involved in the cell cycle, DNA damage responses, autophagy, etc. However, the function and regulatory
Shuyan Li et al.
Archives of insect biochemistry and physiology, 105(1), e21718-e21718 (2020-06-10)
The autophagy process involves a series of autophagy-related (Atg) proteins, which are conserved in eukaryotes. ULK1/Atg1-ATG13/Atg13 is the core protein complex for autophagy initiation in response to nutrient and hormone signaling. However, how Atg13 is regulated to participate in autophagy
Renjun Tu et al.
Current biology : CB, 31(4), 827-839 (2020-12-29)
The niche controls stem cell self-renewal and progenitor differentiation for maintaining adult tissue homeostasis in various organisms. However, it remains unclear whether the niche is compartmentalized to control stem cell self-renewal and stepwise progeny differentiation. In the Drosophila ovary, inner
Ashish Kumar et al.
Scientific reports, 5, 15923-15923 (2015-10-31)
Downregulation of microRNA-31 has been linked with enhanced stress resistance, while its overexpression leads to cell death. In this study, we found mediatory role of microRNA-31 in γ-radiation-induced apoptosis in a model insect cell line Sf9 carrying well-conserved apoptotic machinery.
Wenmei Wu et al.
Cell death discovery, 7(1), 128-128 (2021-06-02)
Protein acetylation plays potential roles in regulating autophagy occurrence. However, it varies greatly between yeast and mammals, and has not been thoroughly investigated in other organisms. Here, we reported that the components of BmAtg8-PE ubiquitin-like system (BmAtg3, BmAtg4, BmAtg7, and
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