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Mary D Frame et al.
Nanotoxicology, 8(8), 867-875 (2013-09-03)
Single-walled carbon nanotubes synthesized with iron (Fe-SWCNT) or gadolinium (Gd-SWCNT) show promise as high performance multimodal contrast and drug-delivery agents. Our purpose was to evaluate potential vasoactive effects of SWCNT. Stable aqueous solutions of Fe-SWCNTs or Gd-SWCNTs were made using
Jingrang Lu et al.
Journal of water and health, 12(4), 763-771 (2014-12-05)
A quantitative polymerase chain reaction assay (115 bp amplicon) specific to Escherichia coli K12 with an ABI(TM) internal control was developed based on sequence data encoding the rfb gene cluster. Assay specificity was evaluated using three E. coli K12 strains
Eduard J van Beers et al.
Circulation research, 116(2), 298-306 (2014-11-08)
Patients with sickle cell disease (SCD) have markers of chronic inflammation, but the mechanism of inflammation and its relevance to patient survival are unknown. To assess the relationship between iron, inflammation, and early death in SCD. Using peripheral blood mononuclear
[Children's iron needs and how we best can protect the child's brain].
Staffan Berglund et al.
Lakartidningen, 111(11), 460-463 (2014-04-12)
Ellinor I B Peerschke et al.
American journal of clinical pathology, 142(4), 506-512 (2014-09-23)
Evaluation of anemia, particularly iron deficiency, in patients with cancer is difficult. This study examined using the hemoglobin content of reticulocytes (RET-He) to rule out iron deficiency, as defined by serum iron studies (transferrin saturation <20%, serum iron <40 μg/dL
Keith P West et al.
JAMA, 312(24), 2649-2658 (2014-12-24)
Maternal micronutrient deficiencies may adversely affect fetal and infant health, yet there is insufficient evidence of effects on these outcomes to guide antenatal micronutrient supplementation in South Asia. To assess effects of antenatal multiple micronutrient vs iron-folic acid supplementation on
Chenyan Lv et al.
Biochemistry, 53(14), 2232-2241 (2014-04-01)
From an evolutionary point of view, plant and animal ferritins arose from a common ancestor, but plant ferritin exhibits different features as compared with the animal analogue. One major difference is that the 4-fold channels naturally occurring in plant ferritin
Thomas A Russo et al.
Infection and immunity, 82(6), 2356-2367 (2014-03-26)
Hypervirulent (hypermucoviscous) Klebsiella pneumoniae (hvKP) strains are an emerging variant of "classical" K. pneumoniae (cKP) that cause organ and life-threatening infection in healthy individuals. An understanding of hvKP-specific virulence mechanisms that enabled evolution from cKP is limited. Observations by our
Mak A Saito et al.
Science (New York, N.Y.), 345(6201), 1173-1177 (2014-09-06)
Marine primary productivity is strongly influenced by the scarcity of required nutrients, yet our understanding of these nutrient limitations is informed by experimental observations with sparse geographical coverage and methodological limitations. We developed a quantitative proteomic method to directly assess
Zille Rubab et al.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 26(1), 19-25 (2015-01-13)
Patients on hemodialysis (HD) are usually anemic because of defective erythropoeisis. Hepcidin is a polypeptide that regulates iron homeostasis and could serve as an indicator of functional iron deficiency in patients with end-stage renal disease (ESRD); this may also aid
Arnold L Demain et al.
Applied microbiology and biotechnology, 73(1), 55-59 (2006-04-20)
When tetanus toxin is made by fermentation with Clostridium tetani, the traditional source of iron is an insoluble preparation called reduced iron powder. This material removes oxygen from the system by forming FeO(2) (rust). When inoculated in a newly developed
S J Geetha et al.
TheScientificWorldJournal, 2013, 315890-315890 (2013-12-10)
Under field conditions, inoculated rhizobial strains are at a survival disadvantage as compared to indigenous strains. In order to out-compete native rhizobia it is not only important to develop strong nodulation efficiency but also increase their competence in the soil
Sohail Amjad et al.
Pakistan journal of pharmaceutical sciences, 27(3), 445-452 (2014-05-09)
In Pakistan, a funded flour fortification program was launched for malnourished population, residing mainly in rural low income areas, but the urban population having comparatively better nutritional as well as economic status was focused wherein excessive intake of fortificants might
Ramesh Kumar et al.
Environmental technology, 35(13-16), 2018-2027 (2014-06-25)
Nanofiltration (NF) of ammoniacal wastewater containing phenol and cyanide has been investigated for effective separation of these hazardous pollutants and for the subsequent downstream chemical treatment resulting in valuable by-product generation. Four different types of composite polyamide commercial NF membranes
Rui C Martins et al.
Environmental technology, 35(17-20), 2380-2388 (2014-08-26)
The presence of surfactants in wastewater composition tends to jeopardize the efficiency of the traditional aerobic treatment processes. In this regard, the application of Fenton's reaction and nanofiltration as single processes and integrated (nanofiltration followed by Fenton's process) was investigated
50 years ago in the Journal of Pediatrics: Iron metabolism in premature infants: II. Prevention of iron deficiency.
Pamela J Kling
The Journal of pediatrics, 164(4), 768-768 (2014-03-22)
Joseph D Mancias et al.
Nature, 509(7498), 105-109 (2014-04-04)
Autophagy, the process by which proteins and organelles are sequestered in double-membrane structures called autophagosomes and delivered to lysosomes for degradation, is critical in diseases such as cancer and neurodegeneration. Much of our understanding of this process has emerged from
Stuart B Krasnoff et al.
Journal of natural products, 77(7), 1685-1692 (2014-07-06)
Under iron-depleted culture conditions, the entomopathogenic fungus Metarhizium robertsii (Bischoff, Humber, and Rehner) (= M. anisopliae) produces a complex of extracellular siderophores including novel O-glycosylated and N-oxidized coprogen-type compounds as well as the known fungal siderophores N(α)-dimethylcoprogen (NADC) and dimerumic
B Clevenger et al.
Anaesthesia, 70 Suppl 1, 20-28 (2014-12-03)
Pre-operative anaemia is a relatively common finding, affecting a third of patients undergoing elective surgery. Traditionally associated with chronic disease, management has historically focused on the use of blood transfusion as a solution for anaemia in the peri-operative period. Data
Theodore M Flynn et al.
Science (New York, N.Y.), 344(6187), 1039-1042 (2014-05-03)
Microbial reduction of ferric iron [Fe(III)] is an important biogeochemical process in anoxic aquifers. Depending on groundwater pH, dissimilatory metal-reducing bacteria can also respire alternative electron acceptors to survive, including elemental sulfur (S(0)). To understand the interplay of Fe/S cycling
Yan Zhang et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(17), E1695-E1704 (2014-04-16)
Eukaryotic ribonucleotide reductases (RNRs) require a diferric-tyrosyl radical (Fe(III)2-Y•) cofactor to produce deoxynucleotides essential for DNA replication and repair. This metallocofactor is an important target of RNR-based therapeutics, although mechanisms of in vivo cofactor assembly, inactivation, and reactivation are poorly
Ina Danquah et al.
Tropical medicine & international health : TM & IH, 19(5), 563-567 (2014-06-06)
Acute symptomatic infection with Giardia duodenalis impairs iron absorption, but iron deficiency may protect against infections caused by various micro-organisms including parasites. We therefore examined the association of G. duodenalis infection and iron deficiency in 575 Rwandan children under 5
Isabelle R Miousse et al.
Radiation research, 182(1), 92-101 (2014-06-25)
There is an increasing need to better understand the long-term health effects of high-linear energy transfer (LET) radiation due to exposure during space missions, as well as its increasing use in clinical treatments. Previous studies have indicated that exposure to
Abigail Trejo-Hernández et al.
The ISME journal, 8(10), 1974-1988 (2014-04-18)
Inter-kingdom and interspecies interactions are ubiquitous in nature and are important for the survival of species and ecological balance. The investigation of microbe-microbe interactions is essential for understanding the in vivo activities of commensal and pathogenic microorganisms. Candida albicans, a
Kurinchi Selvan Gurusamy et al.
The Cochrane database of systematic reviews, 12(12), CD010640-CD010640 (2015-01-01)
Anaemia affects about a quarter of the world's population. An estimated 50% of anaemic people have anaemia due to iron deficiency. To assess the safety and efficacy of iron therapies for the treatment of adults with anaemia who are not
Tea Romih et al.
The Science of the total environment, 508, 76-84 (2014-12-02)
The aim of this study was to determine whether citric acid adsorbed onto cobalt ferrite (CoFe2O4) nanoparticles (NPs) influences the bioavailability of their constituents Co and Fe. Dissolution of Co and Fe was assessed by two measures: (i) in aqueous
Nosratola D Vaziri
Nephrology news & issues, 28(2), 4-5 (2014-03-22)
Loss of blood associated with hemodialysis procedures and laboratory testing, together with impaired iron absorption due to elevation of hepcidin, invariably cause iron deficiency in end-stage renal disease patients. For this reason, nearly all ESRD patients require intravenous iron to
Yatrik M Shah et al.
Gastroenterology, 146(3), 630-642 (2014-01-07)
Iron is required for efficient oxygen transport, and hypoxia signaling links erythropoiesis with iron homeostasis. Hypoxia induces a highly conserved signaling pathway in cells under conditions of low levels of O2. One component of this pathway, hypoxia-inducible factor (HIF), is
Laura M van Staalduinen et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(14), 5171-5176 (2014-04-08)
The enzymes PhnY and PhnZ comprise an oxidative catabolic pathway that enables marine bacteria to use 2-aminoethylphosphonic acid as a source of inorganic phosphate. PhnZ is notable for catalyzing the oxidative cleavage of a carbon-phosphorus bond using Fe(II) and dioxygen
Robert C Hider et al.
Metal ions in life sciences, 13, 229-294 (2014-01-29)
Iron is a redox active metal which is abundant in the Earth's crust. It has played a key role in the evolution of living systems and as such is an essential element in a wide range of biological phenomena, being
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