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Showing 1-30 of 35 results for "gfra ret signaling activator" within Technical Documents
Data Sheet - N0274
common signaling component RET receptor tyrosine
kinase (RTK).4, 5, 6, 7 Neurturin prefers to bind GFRα2
but can also bind GFRα1. NTN forms a complex with
GFRα2 and the Ret PTK activating the RET receptor
Data Sheet - SRP5311
molecules that
transduce signals for cell growth and differentiation.
RET can undergo oncogenic activation in vivo and
in vitro by cytogenetic rearrangement.1 Mutations in the
RET gene are associated with
Data Sheet - N6909
mediates neurturin and GDNF signaling through
Ret. Neuron, 18, 793-802 (1997).
5. Sanicola, M., et al., Glial cell line-derived neuro-
trophic factor-dependent RET activation can be
mediated by two different
Data Sheet - R7782 - Lot 109K0791
RET (658-end), active, GST-tagged, human (R7782) - Datasheet
RET (658-end), active, GST-tagged, human
Precisio Kinase
recombinant, expressed in Sf9 cells
Catalog Number R7782
Lot Number
Data Sheet - R7782 - Lot 050M0842
RET (658-end), active, GST-tagged, human (R7782) - Datasheet
RET (658-end), active, GST-tagged, human
Precisio Kinase
recombinant, expressed in Sf9 cells
Catalog Number R7782
Lot Number
Data Sheet - R7782 - Lot 030M0798
RET (658-end), active, GST-tagged, human (R7782) - Datasheet
RET (658-end), active, GST-tagged, human
Precisio Kinase
recombinant, expressed in Sf9 cells
Catalog Number R7782
Lot Number
Data Sheet - G9290
mediates neurturin and GDNF signaling through
Ret. Neuron, 18, 793-802 (1997).
5. Sanicola, M., et al., Glial cell line-derived
neurotrophic factor-dependent RET activation can
be mediated by two different
Data Sheet - G9415
receptor and the Ret receptor
tyrosine kinase. Nature, 387, 721-724 (1997).
2. Baloh, R. H., et al., TrnR2, a novel receptor that
mediates neurturin and GDNF signaling through
Ret. Neuron, 18, 793
Data Sheet - G1290
by Trk receptor
tyrosine kinases. GDNF, NTN, PSP, and ART mediate
their signals via a common receptor tyrosine kinase,
Ret, but their ligand specificity is determined by a novel
class of glycosylphosphatidylinositol
Data_sheet-SCC464
spontaneously occurring skin
tumor in Ret transgenic mice. The Ret oncogene was originally created by an accidental in vivo recombination of two
human genes, Ret and RFP (the Ret-finger protein, known today as
Data Sheet - G1777
line-derived neurotrophic factor is dependent
on the activation of p70S6 kinase, but independent
of the activation of ERK and up-regulation of Ret in
SH-SY5Y cells. Brain Res., 983, 1-12 (2003).
DT
Data_Sheet-SCC463
spontaneously occurring skin
tumor in Ret transgenic mice. The Ret oncogene was originally created by an accidental in vivo recombination of two
human genes, Ret and RFP (the Ret-finger protein then, known today
Data Sheet - SAB4200762
Anti-Opsin antibody, Mouse monoclonal
clone RET-P1, purified from hybridoma cell culture
Product Number SAB4200762
Product Description
Anti-Opsin antibody, Mouse monoclonal (rhodopsin)
(mouse
Data Sheet - G9540
by Trk receptor
tyrosine kinases. GDNF, NTN, PSP, and ART mediate
their signals via a common receptor tyrosine kinase,
Ret, but their ligand specificity is determined by a novel
class of glycosylphosphatidylinositol
Data Sheet - O4886
MONOCLONAL ANTI-OPSIN,
CLONE RET-P1
Mouse Ascites Fluid
Product Number O 4886
Product Description
Monoclonal Anti-Opsin (rhodopsin) (mouse IgG1
isotype) is derived from the RET-P1 hybridoma
produced
Data Sheet - SAB4200772
with the plasma membrane.3-4 BRAF signaling may be
activated by growth factor binding to receptor tyrosine
kinases upstream as well as other intracellular signals.4
BRAF is mutated at a high frequency
Data Sheet - F9052
FRS2 proteins are tyrosine phos phor-
ylated in response to activation of the RET receptor, a
tyrosine kinase that functions as the signal transducing
receptor for the GDNF.7
Reagent
Anti-FRS2 (
Data Sheet - P9982
preparations,
we recommend determining optimal working dilutions
by titration test.
References
1. Retting, J., et al., EMBO J. 11, 2473 (1992).
2. Vega-Saenz de Miera, E., et al., Proc. R. Soc.
Lond
Panorama Human Protein Functional Array-Signal Transduction
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 8027
STAT1 signal transducer and activator of transcription 1, 91kDa 6772
STAT3 signal transducer and activator of transcription
Phosphotyrosine HTRF® Assay
Suggestions
No signal or
weak signal in
all wells
Missing components or key
steps
Biotinylated-phosphotyrosine
Peptide is no longer active
Phosphotyrosine HTRF® Assay
Suggestions
No signal or
weak signal in
all wells
Missing components or key
steps
Biotinylated-phosphotyrosine
Peptide is no longer active
Product Information Sheet - HPFM2
synovial sarcoma X breakpoint 2 6757
SSX4 synovial sarcoma X breakpoint 4 6759
STAT3 signal transducer and activator of transcription 3 (acute-phase
response factor)
6774
TAF15 TAF15 RNA polymerase
Protein Tyrosine Phosphatases- Potential Roles in Disease
be increased in human
breast cancer samples [29], but has been shown to strongly
suppress ret oncogene activity [30]. The expression of SHP-1
in solid tumors is also variable, and may be related to the
Evaluation of Intracellular Signaling - Downstream Chimeric Antigen Receptors
is phosphorylated upon T cell activation and
may be involved in signal transduction during cellular proliferation and differentiation [54].
Increased Signaling Activity in Third Generation CAR T Cells
Inhibitor Sourcebook 3rd Edition
Acts as a potent and highly selective inhibitor of Janus kinase/signal transducer and
activator of transcription 3 (JAK/STAT3) signaling pathway. It suppresses STAT3 tyrosine
phosphorylation in v-Src-
New Products Flyer- Vol 4 Signaling Feature- NEW! Phosphohistidine Antibody
532729
TAZ Activity Modulator,
TM-25659
A cell permeable, orally bioavailable imidazol-[4,5-b]pyridine derivative that
enhances nuclear localization of transcriptional co-activator with PDZ-binding
Extractables test report: Solutions in polyethylene containers
times of 10.05 min. and 13.00 min. The following
Figure 3.
Acetic acid 100%, batch K40936500
Ret. Time
[min] Mass Proposed structure Comment
10.05 168.188
C12H24
or isomer position of the double
Bulletin - G2041
010560
C16U Signal Transduction 14-3-3 eta NM_011738
C16L Signal Transduction c-fos NM_010234
D16U Signal Transduction CIS1 NM_009895
D16L Signal Transduction CIS2 NM_007706
E16U Signal Transduction
White Paper - The Message in the Marks: Deciphering Cancer Epigenetics
Small Molecules
SRT1720-CAS 925434-55-5, 10 MG, SIRT1 activator 567860-10MG
InSolution™ SRT1720, HCl - CAS 1001645-58-4, 25 mM solution, SIRT1 activator 530748
HMTase Inhibitor V, UNC0224 - CAS 1197196
Cogent μScale Tangential Flow Filtration System User Guide
screen. Starts, stops and adjusts stop the batch settings.
View active alarms.
Stops the buzzer when an alarm or warning is signaled. This button is
visible only if the buzzer function is enabled.
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