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Hao Li et al.
The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA), 17(2), 91-98 (2014-12-23)
To investigate the inhibitory effects of 25-hydroxyvitamin D3 (25(OH)D3)-loaded polylactic acid (PLA) microspheres on inflammatory response in diabetic periodontitis. 25(OH)D3-loaded PLA microspheres were produced using emulsion-solvent evaporation method. Rat bone marrow stromal cells (BMSCs) cultured with Aggregatibacter actinomycetemcomitans in high
Uttam Garg et al.
Journal of clinical laboratory analysis, 26(5), 349-357 (2012-09-25)
Vitamin D plays a vital role not only in bone health but also in pathophysiology of many other body functions. In recent years, there has been significant increase in testing of 25-hydroxyvitamin D (25-OH vitamin D), a marker of vitamin
Michelle L McCully et al.
Journal of immunology (Baltimore, Md. : 1950), 195(1), 96-104 (2015-05-24)
The localization of memory T cells to human skin is essential for long-term immune surveillance and the maintenance of barrier integrity. The expression of CCR8 during naive T cell activation is controlled by skin-specific factors derived from epidermal keratinocytes and
Antrison Morris et al.
Poultry science, 93(8), 1951-1956 (2014-06-17)
Three experiments were conducted to study the effects of 25-hydroxycholecalciferol supplementation on BW gain, IL-1β, and 1α-hydroxylase mRNA expression in different organs of broiler chickens following a lipopolysaccharide (LPS) injection. In experiment I, birds were fed a basal diet supplemented
Kurt D Pennell et al.
Steroids, 95, 24-31 (2014-12-30)
Analytical techniques used to quantify neurosteroids in biological samples are often compromised by non-specificity and limited dynamic range which can result in erroneous results. A relatively rapid and inexpensive gas chromatography-mass spectrometry (GC-MS) was developed to simultaneously measure nine neurosteroids
Cumali Efe et al.
Digestive diseases and sciences, 59(12), 3035-3042 (2014-07-09)
25-Hydroxyvitamin D [25(OH)D] has an important role in fibrosis progression and inflammatory response in patients with various etiologies of chronic liver disease. However, its influence on autoimmune hepatitis (AIH) has not been investigated. We evaluated the association of serum 25(OH)D
J M Wierzbicka et al.
International journal of oncology, 47(3), 1084-1096 (2015-08-12)
Colorectal cancer (CRC) is an emerging global problem with the rapid increase in its incidence being associated with an unhealthy lifestyle. Epidemiological studies have shown that decreased levels of vitamin D3 significantly increases the risk of CRC. Furthermore, negative effects
Nina Karthaus et al.
The Journal of investigative dermatology, 134(5), 1255-1264 (2013-12-20)
Topical application of the vitamin D (VitD) analog calcipotriol is a highly effective standard treatment modality of psoriatic skin lesions. However, the immune modulatory effects of the treatment are incompletely understood. VitD is well known to induce tolerogenic responses in
Janna Nissen et al.
The American journal of clinical nutrition, 101(1), 218-227 (2014-12-21)
Little is known about how the genetic variation in vitamin D modulating genes influences ultraviolet (UV)B-induced 25-hydroxyvitamin D [25(OH)D] concentrations. In the Food with vitamin D (VitmaD) study, we showed that common genetic variants rs10741657 and rs10766197 in 25-hydroxylase (CYP2R1)
K Bratke et al.
Clinical and experimental immunology, 177(1), 366-372 (2014-04-16)
Allergic asthma is a chronic disease of the airways associated with airway hyperresponsiveness, a variable degree of airflow obstruction, airway remodelling and a characteristic airway inflammation. Factors of the vitamin D axis, which include vitamin D metabolites and vitamin D
Kristyna Brabnikova-Maresova et al.
Arthritis research & therapy, 16(5), 460-460 (2014-10-05)
Juvenile idiopathic arthritis (JIA) is a disease associated with loss of bone mass, deterioration in bone mass quality and an increased risk of fractures. The objective of this study was to evaluate factors that predict bone mineral density (BMD) alterations
A Bello et al.
Poultry science, 93(5), 1053-1058 (2014-05-06)
The effects of in ovo injection of 25-hydroxycholecalciferol [25(OH)D3] at various dosages on weight, breaking strength, and ash and mineral concentrations of left tibial bones in Ross × Ross 708 broilers on d 0 and 21 posthatch were investigated. Six
Guido Heine et al.
Journal of immunology (Baltimore, Md. : 1950), 193(3), 1017-1023 (2014-06-22)
Calcitriol (1α,25-dihydroxyvitamin D3) is the active vitamin D metabolite and mediates immunological functions, which are relevant in allergy. Its therapeutic use is limited by hypercalcaemic toxicity. We have previously shown that the activation of the vitamin D receptor inhibits IgE
Maria Samefors et al.
European journal of endocrinology, 170(5), 667-675 (2014-02-13)
Institutionalised elderly people at northern latitudes may be at elevated risk for vitamin D deficiency. In addition to osteoporosis-related disorders, vitamin D deficiency may influence several medical conditions conferring an increased mortality risk. The aim of this study was to
Dae-Jung Kang et al.
Biotechnology letters, 37(9), 1895-1904 (2015-05-23)
Resting cells of Pseudonocardia sp. KCTC 1029BP were used for the bioconversion of vitamin D3 to calcifediol which is widely used to treat osteomalacia and is industrially produced by chemical synthesis. To obtain the maximum bioconversion yield of calcifediol by
Florian Meier et al.
Rapid communications in mass spectrometry : RCM, 28(22), 2461-2470 (2014-10-11)
Unsaturated lipids play a crucial role in cellular processes as signaling factors, membrane building blocks or energy storage molecules. However, adequate mass spectrometry imaging of this diverse group of molecules remains challenging. In this study we implemented silver cationization for
Kazuya Omi et al.
Clinical chemistry, 61(4), 627-635 (2015-02-20)
Small molecules classified as haptens are generally measured by competitive immunoassay, which is theoretically inferior to noncompetitive sandwich immunoassay in terms of sensitivity and specificity. We created a method for developing sandwich immunoassays to measure haptens on the basis of
P Adamczyk et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 47(12), 873-879 (2015-07-03)
Changes in body weight, waist and hip circumferences, body composition, and skeletal status in women after bariatric surgery were evaluated. Thirty-six women [mean age 41.2 ± (SD) 9.5 years, weight 115.7±18.0 kg, and BMI 42.1±5.3 kg/m(2)] underwent laparoscopic sleeve gastrectomy. Bone mineral density
Kevin D Cashman et al.
The Journal of nutrition, 144(7), 1050-1057 (2014-05-16)
Fundamental knowledge gaps in relation to the 3 epimer of 25-hydroxycholecalciferol [3-epi-25(OH)D₃] limit our understanding of its relevance for vitamin D nutrition and health. The aims of this study were to characterize the 3-epi-25(OH)D₃ concentrations in a nationally representative sample
A method for simultaneous determination of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 in human plasma by using two steps of high-performance liquid chromatography
Okano T, et al.
J. Nutr. Sci. Vitaminol., 27(1), 43-54 (1981)
Maha Hoteit et al.
Metabolism: clinical and experimental, 63(7), 968-978 (2014-05-31)
The aim of the current study is to investigate the prevalence of hypovitaminosis D in Lebanese subjects, its robust predictors, evaluate the relationship between 25 hydroxy vitamin D [25(OH)D] and parathyroid hormone levels, and derive desirable vitamin D levels, based
Jennifer R Honda et al.
Journal of medical microbiology, 63(Pt 7), 997-1003 (2014-05-14)
Low levels of the vitamin D-regulated antimicrobial peptide cathelicidin (LL-37) may negatively impact the immune status of human immunodeficiency virus-1 (HIV-1) infected individuals (HIV+). We compared plasma LL-37 levels in healthy controls (HIV-) and HIV+ individuals on or off antiretroviral
Zhican Wang et al.
Endocrinology, 155(6), 2052-2063 (2014-03-20)
25-Hydroxyvitamin D3 (25OHD3) is used as a clinical biomarker for assessment of vitamin D status. Blood levels of 25OHD3 represent a balance between its formation rate and clearance by several oxidative and conjugative processes. In the present study, the identity
Clare Wykes et al.
Annals of hematology, 93(12), 2051-2056 (2014-07-02)
Vitamin D deficiency is common in sickle cell anaemia (SCA, HbSS), although its significance and optimal means of correction are unknown. We conducted an audit to assess the clinical significance of 25-hydroxy vitamin D (25-OHD) deficiency in children with SCA
Development and validation of an LC--MS/MS based method for quantification of 25 hydroxyvitamin D2 and 25 hydroxyvitamin D3 in human serum and plasma
Zhang SW, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 961(1), 62-70 (2014)
Jatinderpal K Sandhu et al.
Biomedical chromatography : BMC, 28(6), 913-917 (2014-05-28)
The accurate and specific measurement of vitamin D is increasingly important for determining the role of vitamin D in the pathogenesis of disease. Liquid chromatography coupled to tandem mass spectrometry (LC/MS/MS) has increasingly become the analytical modality of choice for
Fadia S AlBuhairan et al.
The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 57(3), 263-269 (2015-08-25)
With the increasing burden of noncommunicable disease, adolescence is viewed as an opportune time to prevent the onset of certain behaviors and promote healthy states. Although adolescents comprise a considerable portion of Saudi Arabia's population, they have received insufficient attention
Low 25-hydroxyvitamin D3 serum levels and non-alcoholic fatty liver disease.
L Abenavoli et al.
Minerva medica, 105(2), 175-175 (2014-04-15)
Joseph Schwager et al.
Molecular nutrition & food research, 59(8), 1513-1523 (2015-03-27)
The impact of L-ascorbic acid (L-AA) on the chemokinesis (CK) and chemotaxis (CT) of HL-60 cells and polymorphonuclear cells (PMN) was investigated. HL-60 cells were differentiated with DMSO, retinoic acid (RA), vitamin D, or L-AA. Chemokinesis and chemotaxis of differentiated
Reply to T Weishaar.
Ramon A Durazo-Arvizu et al.
The American journal of clinical nutrition, 101(2), 413-414 (2015-02-04)
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