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Mohammad Behbahani et al.
Journal of chromatography. A, 1308, 25-31 (2013-08-21)
A simple, rapid, and efficient method, based on surfactant assisted dispersive liquid-liquid microextraction (SA-DLLME), followed by high performance liquid chromatography (HPLC) has been developed for simultaneous preconcentration and trace detection of zonisamide and carbamazepine in biological samples. A conventional cationic
Anbin Zhang et al.
Transplant international : official journal of the European Society for Organ Transplantation, 27(10), 1077-1085 (2014-05-09)
Ischemia reperfusion (IR) injury is a major issue in cardiac transplantation and inflammatory processes play a major role in myocardial IR injury. Necrostatin-1 (Nec-1) is a small molecule capable of inhibiting RIP1 kinase activity and attenuates inflammation-mediated tissue injury. In
Jiabei Liang et al.
Scientific reports, 5, 7985-7985 (2015-01-24)
Ginseng, which is the root of Panax ginseng (Araliaceae), has been used in Oriental medicine as a stimulant and dietary supplement for more than 7,000 years. Older ginseng plants are substantially more medically potent, but ginseng age can be simulated
Rong-Li Liao et al.
BMC plant biology, 15, 146-146 (2015-06-18)
Natural hybridization in plants is universal and plays an important role in evolution. Based on morphology it has been presumed that hybridization occurred in the genus Buddleja, though genetic studies confirming this assumption have not been conducted to date. The
Jiyun Song et al.
ACS applied materials & interfaces, 7(33), 18460-18466 (2015-08-05)
We report a unique nanostructured electron-selective interlayer comprising of In-doped ZnO (ZnO:In) and vertically aligned CdSe tetrapods (TPs) for inverted polymer:fullerene bulkheterojunction (BHJ) solar cells. With dimension-controlled CdSe TPs, the direct inorganic electron transport pathway is provided, resulting in the
Mohammad Yahya Hanafi-Bojd et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 89, 248-258 (2014-12-17)
Recent studies with inorganic nanoparticles modified with functional groups have demonstrated improvement in drug delivery into cancer cells. In the present study, we prepared, characterized, and evaluated mesoporous silica nanoparticles (MSNs) as carriers for epirubicin hydrochloride (EPI) in order to
Nick Frazier et al.
Molecular pharmaceutics, 12(5), 1605-1614 (2015-04-04)
Previously, water-soluble N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers have been used with gold nanorod (GNR) mediated plasmonic photothermal therapy (PPTT) to induce hyperthermia (43 °C for 10 min) and have been shown to improve delivery of hydrophobic drugs to treat cancer. However, it
Jiao Deng et al.
Plant & cell physiology, 56(8), 1546-1555 (2015-05-29)
Lotus is a vital aquatic ornamental plant with different flower colors. To explore the flower coloration mechanism in lotus, the constituents and contents of pigments in two lotus cultivars with red and white flowers were analyzed. Although flavones and flavonols
Eduardo Augusto Brosco Famá et al.
Clinica chimica acta; international journal of clinical chemistry, 437, 155-160 (2014-08-02)
Preeclampsia is a multisystem disorder whose etiology remains unclear. It is already known that circulation of soluble fms-like tyrosine kinase-1 (sFlt-1) is directly involved in pre-eclampsia development. However, the molecular mechanisms involved with sFlt-1 shedding are still unidentified. We identified
Katelyn T Gause et al.
ACS nano, 9(3), 2433-2444 (2015-02-26)
The development of subunit antigen delivery formulations has become an important research endeavor, especially in cases where a whole cell vaccine approach has significant biosafety issues. Particle-based systems have shown particular efficacy due to their inherent immunogenicity. In some cases
Natássia Albuquerque Ribeiro et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 63(7), 569-580 (2014-03-19)
Marine algae are abundant sources of sulfated polysaccharides with various biological activities. Consequently, their biomolecules are of great of commercial interest. In this study, we investigated the potential antinociceptive activity of a sulfated polysaccharide obtained from the green seaweed Caulerpa
Hussaini Syed Sha Qhattal et al.
ACS nano, 8(6), 5423-5440 (2014-05-09)
Hyaluronan-grafted liposomes (HA-liposomes) preferentially target CD44-overexpressing tumor cells in vitro via receptor-mediated endocytosis. We investigated the pharmacokinetics and biodistribution of HA-liposomes with various sizes of HA (MW 5-8, 50-60, and 175-350 kDa) in mice. Incorporation of negatively charged HA on
Ali Akbar Asgharinezhad et al.
Analytica chimica acta, 844, 80-89 (2014-08-31)
In this study, diverse types of Fe3O4 nanocomposites modified by polyaniline, polypyrrole, and aniline-pyrrole copolymer were synthesized through chemical oxidative polymerization process for dispersive-μ-solid phase extraction (D-μ-SPE) in the presence of various dopants. The results showed that the nanocomposite modified
Cui Li et al.
Investigative ophthalmology & visual science, 55(10), 6886-6900 (2014-10-10)
To determine if IL-17 regulates Mer tyrosine kinase-positive (MerTK+) cells in Pseudomonas aeruginosa keratitis. Interleukin 17 was tested in normal and infected cornea of susceptible C57BL/6 and resistant BALB/c mice. The latter were treated with recombinant mouse (rm) IL-17; both
Yi Liu et al.
BMC plant biology, 15, 160-160 (2015-06-26)
The flavan-3-ols catechin and epicatechin, and their polymerized oligomers, the proanthocyanidins (PAs, also called condensed tannins), accumulate to levels of up to 15 % of the total weight of dry seeds of Theobroma cacao L. These compounds have been associated with
Michelle A Nguyen et al.
ACS applied materials & interfaces, 7(24), 13238-13250 (2015-05-27)
We report a synthetic approach to form octahedral Cu2O microcrystals with a tunable edge length and demonstrate their use as catalysts for the photodegradation of aromatic organic compounds. In this particular study, the effects of the Cu(2+) and reductant concentrations
Xiaolu Zhuo et al.
ACS nano, 9(7), 7523-7535 (2015-07-03)
We report on a method for the preparation of uniform and length-variable Ag nanorods through anisotropic Ag overgrowth on high-purity Au nanobipyramids. The rod diameters can be roughly tailored from ∼20 nm to ∼50 nm by judicious selection of differently
Brandy J Johnson et al.
PloS one, 7(11), e50356-e50356 (2012-12-12)
The potential for encapsulating RNA within tunable, semi-permeable structures for storage and transportation purposes offers an interesting approach to the reduction of stringent storage requirements that often hamper the field application of genetic analysis methods. In this study, we assessed
Gautam Das et al.
International journal of nanomedicine, 10 Spec Iss, 165-178 (2015-09-09)
In this work, three different spherulitic nanostructures Cu-CuOA, Cu-CuOB, and Cu-CuOC were synthesized in water-in-oil microemulsions by varying the surfactant concentration (30 mM, 40 mM, and 50 mM, respectively). The structural and morphological characteristics of the Cu-CuO nanostructures were investigated
Tanmay Bera et al.
ACS applied materials & interfaces, 7(26), 14528-14535 (2015-06-16)
We report that liquid crystal elastomers (LCEs), often portrayed as artificial muscles, serve as scaffolds for skeletal muscle cell. A simultaneous microemulsion photopolymerization and cross-linking results in nematic LCE microspheres 10-30 μm in diameter that when conjoined form a LCE
Yongbiao Hao et al.
Evidence-based complementary and alternative medicine : eCAM, 2014, 569587-569587 (2014-08-15)
Xilei san (XLS), a herbal preparation widely used in China for erosive and ulcerative diseases, has been shown to be effective in ulcerative colitis (UC). The present experiments were conducted to assess its efficacy and determine its mechanism of action
Jae-Min Ha et al.
Soft matter, 11(29), 5821-5827 (2015-06-11)
We have investigated the distributions of individually isolated and hydrophilically functionalized single-walled carbon nanotubes (p-SWNTs) in the Pluronic L121-water system at the reverse hexagonal phase using small-angle X-ray scattering (SAXS) and contrast-matched small-angle neutron scattering (SANS) measurements. As the p-SWNT-L121-water
A T Nasr et al.
Physics in medicine and biology, 60(12), 4665-4683 (2015-05-29)
Radiochromic leuco crystal violet (LCV) micelle gel dosimeters are promising three-dimensional radiation dosimeters because of their spatial stability and suitability for optical readout. The effects of surfactant type and surfactant concentration on dose sensitivity of LCV micelle gels are tested
Jingzu Sun et al.
Scientific reports, 5, 10477-10477 (2015-07-21)
Hirsutella rhossiliensis and H. minnesotensis are endoparasitic fungi of the second-stage juvenile (J2) of the soybean cyst nematode (Heterodera glycines) in nature. They also parasitize both H. glycines J2 and Caenorhabditis elegans on agar plates. Agrobacterium tumefaciens-mediated transformation conditions were
Natalia Barkalina et al.
Nanomedicine (London, England), 10(10), 1539-1553 (2015-05-27)
This study aimed to investigate the effects of actively targeting mesoporous silica nanoparticles (MSNPs) toward mammalian sperm with a cell-penetrating peptide (C105Y), with subsequent analysis of binding rates and nano-safety profiles. Boar sperm were exposed in vitro to C105Y-functionalized MSNPs
R C Beier et al.
Journal of applied microbiology, 118(2), 326-342 (2014-11-29)
To evaluate susceptibility of Pseudomonas aeruginosa veterinary isolates to antibiotics and disinfectants. Pseudomonas aeruginosa isolates collected from dogs (n = 155) and other animals (n = 20) from sixteen states during 1994-2003 were tested for susceptibility. Most isolates were resistant
Joanito Liberti et al.
Molecular ecology, 24(12), 3151-3169 (2015-04-25)
Bacterial symbionts are important fitness determinants of insects. Some hosts have independently acquired taxonomically related microbes to meet similar challenges, but whether distantly related hosts that live in tight symbiosis can maintain similar microbial communities has not been investigated. Varying
Paul J Ackerman et al.
Nature communications, 6, 6012-6012 (2015-01-22)
Some of the most exotic condensed matter phases, such as twist grain boundary and blue phases in liquid crystals and Abrikosov phases in superconductors, contain arrays of topological defects in their ground state. Comprised of a triangular lattice of double-twist
Xiaoqian Chu et al.
PloS one, 10(11), e0143022-e0143022 (2015-11-13)
WRKY transcription factors constitute a very large family of proteins in plants and participate in modulating plant biological processes, such as growth, development and stress responses. However, the exact roles of WRKY proteins are unclear, particularly in non-model plants. In
Aleeza C Gerstein et al.
mBio, 6(5), e01340-e01315 (2015-10-16)
Cryptococcus neoformans is a major life-threatening fungal pathogen. In response to the stress of the host environment, C. neoformans produces large polyploid titan cells. Titan cell production enhances the virulence of C. neoformans, yet whether the polyploid aspect of titan cells is
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