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hpa022904

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Dual localization of glutathione S-transferase in the cytosol and mitochondria: implications in oxidative stress, toxicity and disease
Raza H
FEBS Journal, 278(22), 4243-4251 (2011)
Alison J Shield et al.
Genomics, 95(5), 299-305 (2010-03-03)
The level of glutathione transferase Kappa (GSTK1-1) has been correlated with obesity (Liu et.al. 2008 PNAS 105: 18302-7) and a polymorphism in the hGSTK1 promoter has been associated with insulin secretion and fat deposition (Gao et al 2009 Endocr J
Lalida Rojanathammanee et al.
The journals of gerontology. Series A, Biological sciences and medical sciences, 69(10), 1199-1211 (2013-11-29)
Ames dwarf mice are deficient in growth hormone (GH), prolactin, and thyroid-stimulating hormone and live significantly longer than their wild-type (WT) siblings. The lack of GH is associated with stress resistance and increased longevity. However, the mechanism underlying GH's actions
Anna Robinson et al.
The Biochemical journal, 379(Pt 3), 541-552 (2004-01-08)
The Kappa class of GSTs (glutathione transferases) comprises soluble enzymes originally isolated from the mitochondrial matrix of rats. We have characterized a Kappa class cDNA from human breast. The cDNA is derived from a single gene comprising eight exons and
Downregulation of GSTK1 is a common mechanism underlying hypertrophic cardiomyopathy
Sasagawa S, et al.
Frontiers in Pharmacology, 7, 162-162 (2016)
Fabrice Morel et al.
The Journal of biological chemistry, 279(16), 16246-16253 (2004-01-27)
Kappa class glutathione S-transferase (GST) cDNA sequences have been identified in rat, mouse, and human. In the present study, we determined the structure and chromosomal location of the human GST Kappa 1 (hGSTK1) gene, characterized the protein, and demonstrated its
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