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Showing 1-9 of 9 results for "HSTCMAG28SPMX21" within Papers
Parisa Afshari et al.
PloS one, 12(9), e0183854-e0183854 (2017-09-09)
We previously reported a 84-Kb hemi-deletion copy number variant at the SLC1A1 gene locus that reduces its expression and appeared causally linked to schizophrenia. In this report, we characterize the in vivo and in vitro consequences of reduced expression of
Kavita Mathi et al.
Clinical immunology (Orlando, Fla.), 231, 108828-108828 (2021-08-24)
COVID-19 is characterized by a dysregulation of inflammatory cytokines ultimately resulting a cytokine storm that can result in significant morbidity and mortality. We developed an in-vitro assay using activated peripheral blood mononuclear cells (PBMCs) stimulated with lipopolysaccharide (LPS) or CD3 + CD28
Zhiwu Jiang et al.
Biomarker research, 10(1), 13-13 (2022-03-26)
Adoptive cell therapy (ACT) is a particularly promising area of cancer immunotherapy, engineered T and NK cells that express chimeric antigen receptors (CAR) are being explored for treating hematopoietic malignancies but exhibit limited clinical benefits for solid tumour patients, successful
Marian Pavuk et al.
Environmental health perspectives, 127(12), 127007-127007 (2019-12-21)
In 2014, we conducted a longitudinal study [Anniston Community Health Survey (ACHS II)] 8 y after the baseline (ACHS I). We investigated the relationship between persistent chlorinated compounds and hypertension in residents living around the former polychlorinated biphenyl (PCB) production
Sophia Kwon et al.
Annals of the American Thoracic Society, 13(8), 1253-1261 (2016-04-21)
The World Trade Center (WTC) collapse generated caustic airborne particulates that caused chronic rhinosinusitis in exposed Fire Department of New York firefighters. Surgery was performed when symptoms remained uncontrolled despite medical management. To identify predictors of surgical intervention for chronic
Liang Zhao et al.
Environmental health perspectives, 130(2), 27007-27007 (2022-02-15)
Insulin resistance (IR) affects the development of type 2 diabetes mellitus (T2DM), which is also influenced by accumulated fine particle air pollution [particulate matter (PM) with aerodynamic diameter of <2.5μm (PM2.5)] exposure. Previous experimental and epidemiological studies have proposed several
Mauro Castellarin et al.
JCI insight, 5(14) (2020-06-17)
Off-tumor targeting of human antigens is difficult to predict in preclinical animal studies and can lead to serious adverse effects in patients. To address this, we developed a mouse model with stable and tunable human Her2 (hHer2) expression on normal
María Juncal-Ruiz et al.
Journal of neuroinflammation, 15(1), 63-63 (2018-03-02)
Low-grade inflammation has been repeatedly associated with both excess weight and psychosis. However, no previous studies have addressed the direct effect of body mass index (BMI) on basal serum cytokines in individuals with first-episode psychosis (FEP). The aim of this
Ankura Singh et al.
Chest, 154(6), 1301-1310 (2018-07-22)
Previously healthy firefighters with World Trade Center (WTC) dust exposure developed airway disease. Risk factors for irritant-associated asthma/COPD overlap are poorly defined. This study included 2,137 WTC-exposed firefighters who underwent a clinically indicated bronchodilator pulmonary function test (BD-PFT) between 9/11/2001
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