Showing 1-30 of 34 results for "I2273"
T Mohammad et al.
Photochemistry and photobiology, 59(2), 189-196 (1994-02-01)
Naked, infectious single-stranded (ss) and double-stranded (ds) DNA from phages S13 and G4 were irradiated with 308 nm UV radiation in the absence and presence of several photobiologically active compounds: E- and Z-urocanic acid (E- and Z-UA), their methyl esters...
J G Bell et al.
Prostaglandins, leukotrienes, and essential fatty acids, 63(1-2), 21-25 (2000-09-06)
The fatty acid compositions of red blood cell (RBC) phospholipids from a patient with autistic spectrum disorder (ASD) had reduced percentages of highly unsaturated fatty acids (HUFA) compared to control samples. The percentage of HUFA in the RBC from the...
M Kavanoor et al.
Biophysical chemistry, 66(1), 43-55 (1997-05-21)
The pH dependence of the association of apo trp repressor with the series of ligands, tryptophan, tryptamine, indole propionic acid (IPA), and trans-beta-indole acrylic acid (IAA), has been studied using fluorescence titrations and isothermal titration microcalorimetry (ITC). The purpose of...
G Bogosian et al.
Gene, 133(1), 17-22 (1993-10-29)
Mutant strains selected as survivors of the lethal overexpression of a plasmid-encoded bovine somatotropin-beta-galactosidase fusion protein were found to include instances where an IS10 element had transposed from the chromosome into the fusion protein structural gene on the plasmid. Two...
K E Dixon et al.
FEMS microbiology letters, 106(2), 135-138 (1993-01-15)
A hybrid trpPO:lacO regulatory sequence was cloned upstream of a promoterless lacZ gene and recombined onto a lambda bacteriophage. Escherichia coli lysogens representing the four possible phenotypes for lacI and trpR were constructed and the synthesis of beta-galactosidase was assayed...
S J Farrow et al.
Photochemistry and photobiology, 51(3), 263-271 (1990-03-01)
E-beta-Indol-3-ylacrylic acid (IA), radiolabelled at the 2 position with 14C, and calf thymus DNA have been irradiated with UV light (lambda greater than 280 nm) in phosphate buffer (pH 7.0). Re-isolation of the DNA indicates covalent binding of IA at...
Zhenying Zhang et al.
Rapid communications in mass spectrometry : RCM, 18(18), 2146-2154 (2004-08-19)
Six novel poly(phenylenevinylene) (PPV) derivatives carrying butoxy or myrtanyl groups, including poly(2-butoxy-m-phenylenevinylene) (Bu-MPV), poly(2,5-dibutoxy-p-phenylenevinylene-alter-p-phenylenevinylene) (Bu-PPPV), poly(2,5-dibutoxy-p-phenylenevinylene-alter-m-phenylenevinylene) (Bu-PMPV), poly(2-myrtanyl-m-phenylenevinylene) (Myr-MPV), poly(2,5-dimyrtanyl-p-phenylenevinylene-alter-p-phenylenevinylene) (Myr-PPPV), and poly(2,5-dimyrtanyl-p-phenylenevinylene-alter-m-phenylenevinylene) (Myr-PMPV), were characterized by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS). The repeat unit mass and the...
Protein-ligand interactions: exchange processes and determination of ligand conformation and protein-ligand contacts.
L Y Lian et al.
Methods in enzymology, 239, 657-700 (1994-01-01)
Application of the E. coli trp promoter.
D G Yansura et al.
Methods in molecular biology (Clifton, N.J.), 62, 55-62 (1997-01-01)
Patricia Casino et al.
Biochemistry, 46(26), 7728-7739 (2007-06-15)
Substrate channeling in the tryptophan synthase bienzyme complex from Salmonella typhimurium is regulated by allosteric interactions triggered by binding of ligand to the alpha-site and covalent reaction at the beta-site. These interactions switch the enzyme between low-activity forms with open...
Deuterated nucleotides as chemical probes of RNA structure: a detailed protocol for the enzymatic synthesis of a complete set of nucleotides specifically deuterated at ribose carbons
Azad R, et al.
ScienceOpen Research (2015)
Eduard Dolusić et al.
Journal of medicinal chemistry, 54(15), 5320-5334 (2011-07-06)
Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO) is an important mechanism of peripheral immune tolerance contributing to tumoral immune resistance. IDO inhibition is thus an active area of research in drug development. Recently, our group has shown that tryptophan 2,3-dioxygenase...
Jungwoon Lee et al.
Angewandte Chemie (International ed. in English), 51(50), 12509-12513 (2012-11-06)
Booster of pluripotency: RSC133, a new synthetic derivative of indoleacrylic acid/indolepropionic acid, exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. Furthermore it potently improves the reprogramming of human somatic cells into a pluripotent state and aids the growth...
[Tryptophan metabolism by the indoleacrylic acid pathway].
E Marklová
Ceskoslovenska farmacie, 37(6), 275-280 (1988-07-01)
Effective induction of tryptophan promoter under glucose starvation
MIZUTANI S, et al.
J. Chem. Eng. Jpn., 21(6), 658-660 (1988)
V Ramesh et al.
European journal of biochemistry, 235(3), 804-813 (1996-02-01)
The binding of the corepressors tryptophan and 5-methyltryptophan and of the inducers 3-indolepropionate, 3-indoleacrylate and 5-methylindole to the Escherichia coli trp repressor have been studied by 1H-NMR spectroscopy. Identification of the resonances of the protons of bound ligands and their...
Meng-Hui Wang et al.
Journal of microbiology and biotechnology, 23(2), 260-266 (2013-02-16)
Rhodococcus sp. strain p52, a previously isolated dibenzofuran degrader, could effectively inhibit the growth of cyanobacteria, including species of Microcystis, Anabaena, and Nodularia. When strain p52 was inoculated at the concentration of 7.7×10(7) CFU/ml, 93.5% of exponentially growing Microcystis aeruginosa...
E Marklová
Amino acids, 17(4), 401-413 (2000-03-09)
In addition to the main catabolic routes of tryptophan (Trp), there exist minor and less thoroughly investigated pathways; one of these leads to indolylacrylic acid (IAcrA). IAcrA is a plant growth hormone, whereas its biological role in animals is still...
Identification and functional analyses of differentially expressed metabolites in early stage endometrial carcinoma
Shi K, et al.
Cancer Science, 109(4), 1032-1043 (2018)
J K Johnson et al.
Biochemistry, 33(15), 4738-4744 (1994-04-19)
In a previous paper, we demonstrated that the medium-chain fatty acyl-CoA dehydrogenase-catalyzed (MCAD-catalyzed) reductive half-reaction of indolepropionyl-CoA proceeds via formation of a chromophoric intermediary species "X" (absorption maximum = 400 nm) and proposed that the decay of this species might...
Qian Han et al.
Journal of medicinal chemistry, 52(9), 2786-2793 (2009-04-03)
Human kynurenine aminotransferase I (hKAT I) catalyzes the formation of kynurenic acid, a neuroactive compound. Here, we report three high-resolution crystal structures (1.50-1.55 A) of hKAT I that are in complex with glycerol and each of two inhibitors of hKAT...
S O Hwang et al.
Biotechnology progress, 6(1), 48-50 (1990-01-01)
An approach to the optimization of product yield in an inducible inclusion body-producing system is presented. Following induction by indoleacrylic acid (IAA) of a trpLE-HIVgp41 fusion protein, we found a large increase in culture turbidity and single-cell dry weight. After...
Indeok Hwang et al.
Plant molecular biology, 73(6), 629-641 (2010-05-18)
Shoot branching and growth are controlled by phytohormones such as auxin and other components in Arabidopsis. We identified a mutant (igi1) showing decreased height and bunchy branching patterns. The phenotypes reverted to the wild type in response to RNA interference...
D Hu et al.
Archives of biochemistry and biophysics, 305(2), 588-594 (1993-09-01)
Trans-beta-Indoleacrylic acid (IAA) binds with moderately high affinity to the dimeric protein, trp aporepressor from Escherichia coli. IAA is itself nonfluorescent, and, upon binding, IAA quenches approximately 95% of the intrinsic tryptophan fluorescence of the protein. Since there is an...
Pratibha Vyas et al.
Journal of microbiology and biotechnology, 20(12), 1724-1734 (2011-01-05)
A phosphate-solubilizing bacterial strain isolated from Hippophae rhamnoides rhizosphere was identified as Rahnella sp. based on its phenotypic features and 16S rRNA gene sequence. The bacterial strain showed the growth characteristics of a cold-adapted psychrotroph, with the multiple plant growth-promoting...
Shengnan Shi et al.
Bioresource technology, 193, 281-287 (2015-07-06)
Arthrobacter sp. W1 was used to characterize the pathways involved in cometabolic degradation of carbazole (CA) with phenol as the primary substrate. To clarify the upper pathway of cometabolic degradation CA, Escherichia coli strain BL21 expressing phenol hydroxylase from strain...
[Metabolism of indolylacrylic acid. III. Effect of intestinal microbes on the excretion of indolylacryloylglycine in urine].
E Marklová et al.
Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum, 29(4-5), 451-455 (1986-01-01)
Indoleacrylic acid produced by commensal peptostreptococcus species suppresses inflammation
Wlodarska M, et al.
Cell host & microbe, 22(1), 25-37 (2017)
Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats
Zhao ZH, et al.
Experimental & Molecular Medicine, 51(9), 1-14 (2019)
High-expression vectors with multiple cloning sites for construction of trpE fusion genes: pATH vectors.
T J Koerner et al.
Methods in enzymology, 194, 477-490 (1991-01-01)

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