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I8135

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The importance of natural IgM: scavenger, protector and regulator
Ehrenstein MR and Notley, Clare A
Nature Reviews: Immunology, 10(11), 778-778 (2010)
IgE b immune complexes activate macrophages through FcgammaRIV binding
Hirano M, et al.
Nature Immunology, 8(7), 762-762 (2007)
Protective roles of natural IgM antibodies
Gronwall C, et al.
Frontiers in Immunology, 3, 66-66 (2012)
Jonathan R Weinstein et al.
Glia, 56(1), 16-26 (2007-10-03)
Lipopolysaccharide (LPS/endotoxin) is a potent immunologic stimulant. Many commercial-grade reagents used in research are not screened for LPS contamination. LPS induces a wide spectrum of proinflammatory responses in microglia, the immune cells of the brain. Recent studies have demonstrated that...
Lipopolysaccharide is a frequent and significant contaminant in microglia-activating factors
Weinstein JR, et al.
Glia, 56(1), 16-26 (2008)
E J Wiersma et al.
Journal of immunology (Baltimore, Md. : 1950), 160(12), 5979-5989 (1998-06-24)
Previous studies have discerned two forms of polymeric mouse IgM: moderately cytolytic (complement-activating) pentamer, which contains J chain, and highly cytolytic hexamer, which lacks J chain. To investigate the relationships among polymeric structure, J chain content, and cytolytic activity, we...
Emerging functions of natural IgM and its Fc receptor FCMR in immune homeostasis
Wang H, et al.
Frontiers in Immunology, 7, 99-99 (2016)
Masayuki Hirano et al.
Nature immunology, 8(7), 762-771 (2007-06-15)
Because functional analysis of Fc receptors (FcRs) relies heavily on mouse models, the identification of another Fcgamma receptor is particularly noteworthy. We demonstrate that FcgammaRIV, identified here as the mouse ortholog of primate FcgammaRIII, required association of the FcR gamma-chain...