Showing 1-30 of 151 results for "IRMM523B"
M Naoi et al.
Mechanisms of ageing and development, 111(2-3), 175-188 (2000-02-03)
Dopamine neurons in the substantia nigra of human brain are selectively vulnerable and the number decline by aging at 5-10% per decade. Enzymatic and non-enzymatic oxidation of dopamine generates reactive oxygen species, which induces apoptotic cell death in dopamine neurons....
K J Bär et al.
Neurobiology of aging, 24(2), 333-338 (2002-12-25)
Increasing evidence suggests an interaction of oxidative stress and the formation of advanced glycation end products (AGE) in the onset and progression of Alzheimer's disease. We studied levels of pentosidine and N(epsilon)-(carboxymethyl)-lysine (CML) in serum and cerebrospinal fluid (CSF) of...
Jicheng Hu et al.
Environmental pollution (Barking, Essex : 1987), 193, 6-12 (2014-07-02)
Unintentionally produced persistent organic pollutants (UP-POPs) were determined in ambient air from around five secondary non-ferrous metal processing plants in China, to investigate the potential impacts of the emissions of these plants on their surrounding environments. The target compounds were...
Zulfiqar Ahmad et al.
Biochemistry, 53(47), 7376-7385 (2014-11-07)
This paper describes the role of α-subunit VISIT-DG sequence residue αThr-349 in the catalytic sites of Escherichia coli F1Fo ATP synthase. X-ray structures show the highly conserved αThr-349 in the proximity (2.68 Å) of the conserved phosphate binding residue βR182...
Thierry Deschamps et al.
Optics express, 21(7), 8382-8392 (2013-04-11)
Using a combination of experimental techniques such as optical absorption, Raman scattering, continuous wave and pulse Electron Spin Resonance (ESR), we characterize a set of γ-irradiated Yb(3+) doped silica glass preforms with different contents of phosphorous and aluminum. We demonstrate...
Qi Chen et al.
Plant physiology and biochemistry : PPB, 70, 504-511 (2013-07-19)
Our previous study showed that citrate excretion coupled with a concomitant release of protons was involved in aluminum (Al) resistance in the broad bean. Furthermore, genes encoding plasma membrane (PM) H(+)-ATPase (vha2) and the 14-3-3 protein (vf14-3-3b) were up-regulated by...
Anna Walter et al.
Neurobiology of aging, 25(10), 1299-1303 (2004-10-07)
Experimental and clinical studies give evidence for breakdown of membrane phospholipids during neurodegeneration. In the present study, we measured the levels of glycerophosphocholine (GPCh), phosphocholine (PCh), and choline, that is, water-soluble metabolites of phosphatidylcholine (PtdCho), in human cerebrospinal fluid (CSF)....
Y Miura
The Kurume medical journal, 47(4), 267-272 (2001-02-24)
Plasma beta-phenylethylamine (PEA) levels were determined in 27 patients with Parkinson's disease (PD) in order to evaluate its relation with the severity or clinical course of PD. The plasma PEA concentrations in PD patients were significantly lower (mean +/- SD...
Norbert W Lutz et al.
PloS one, 2(7), e595-e595 (2007-07-06)
Multiple sclerosis (MS), an inflammatory disease of the central nervous system, manifests itself in numerous forms and stages. A number of brain metabolic alterations have been reported for MS patients vs. control subjects. However, metabolite profiles of cerebrospinal fluid (CSF)...
C A Shaw et al.
Immunologic research, 56(2-3), 304-316 (2013-04-24)
We have examined the neurotoxicity of aluminum in humans and animals under various conditions, following different routes of administration, and provide an overview of the various associated disease states. The literature demonstrates clearly negative impacts of aluminum on the nervous...
Juseok Lee et al.
Journal of biomedical nanotechnology, 9(2), 295-298 (2013-05-01)
Cell responses to surface and contact cell guidance are of great interest in bio-applications especially on nano- and micro scale features. Recently we showed selective cell responses on Al/Al2O3, bi-phasic nanowires (NWs). In this context, Al/Al2O3 NWs were synthesized by...
Stephen C Bondy
Toxicology, 315, 1-7 (2013-11-06)
Aluminum is one of the most common metal elements in the earth's crust. It is not an essential element for life and has commonly been thought of as a rather inert and insoluble mineral. Therefore, it has often been regarded...
K I Bohuts'ka et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 60(1), 91-97 (2014-05-09)
Taking into consideration the nanodimension of functional components of living cells, the application of nanotechnology in the biomedical purposes is currently an urgent task. One of these directions is the use of aluminum nanoparticles for molecular diagnostics, targeted delivery of...
Mutlu Ozcan et al.
The journal of adhesive dentistry, 15(3), 211-214 (2013-05-24)
To evaluate the effect of nozzle distance, nozzle angle, and deposition duration on the silica content attained on zirconia by air abrasion. Disk-shaped zirconia (LAVA, 3M ESPE) (diameter: 10 mm, thickness: 2 mm) specimens (N = 54) were obtained. They...
Wilberth Poot-Poot et al.
IUBMB life, 63(10), 864-872 (2011-09-10)
An early response of plants to environmental signals or abiotic stress suggests that the phospholipid signaling pathway plays a pivotal role in these mechanisms. The phospholipid signaling cascade is one of the main systems of cellular transduction and is related...
Susan Peters et al.
Occupational and environmental medicine, 70(12), 864-868 (2013-10-22)
During the 1950s and 1960s, aluminium dust inhalation was used as a potential prophylaxis against silicosis in underground miners, including in Australia. We investigated the association between aluminium dust inhalation and cardiovascular, cerebrovascular and Alzheimer's diseases in a cohort of...
Lauren Nozomi Marques Yabuki et al.
Environmental monitoring and assessment, 186(2), 961-969 (2013-09-21)
Studies concerning the lability and bioavailability of trace metals have played a prominent role in the search for contamination of water resources. This work describes the first application yet of the diffusive gradients in thin films technique (DGT) to the...
Caitlin Carney et al.
Journal of the American Academy of Dermatology, 69(4), 578-582 (2013-07-17)
Laser treatment has emerged as a novel treatment modality for onychomycosis. We sought to determine thermal response and optical effects of a submillisecond neodymium:yttrium-aluminum-garnet (Nd:YAG) 1064-nm laser on common fungal nail pathogens, and the clinical efficacy and safety of the...
C E Shaw et al.
Journal of neurology, 242(2), 53-58 (1995-01-01)
Magnetic resonance imaging of multiple sclerosis (MS) patients often shows active inflammatory lesions despite clinical remission. No immunological marker of disease activity has been identified in these patients. Concentrations of neopterin, interleukin-2 (IL-2), soluble interleukin-2 receptor (sIL-2R) and tumour necrosis...
S Engelborghs et al.
Neurochemical research, 28(8), 1145-1150 (2003-07-02)
To study changes in amino acid metabolism and biogenic amines in Parkinson's disease, we set up a prospective study and measured biogenic amines, their main metabolites, and 22 different amino acids, in cerebrospinal fluid of Parkinson's disease patients (n =...
Min-Chul Jun et al.
Journal of nanoscience and nanotechnology, 13(5), 3403-3407 (2013-07-19)
Transparent conducting oxide (TCO) materials with high transmittance and good electrical conductivity have been attracted much attention due to the development of electronic display and devices such as organic light emitting diodes (OLEDs), and dye-sensitized solar cells (DSSCs). Aluminum doped...
Takashi Abe et al.
Journal of neuroscience research, 70(3), 447-450 (2002-10-23)
To investigate the possible role of oxidative RNA damage in the pathogenesis of Alzheimer's disease (AD), the concentrations of the oxidative stress marker 8-hydroxyguanosine (8-OHG) were measured in the cerebrospinal fluid (CSF) and the serum of patients with AD and...
Jae Chun Lee et al.
Journal of nanoscience and nanotechnology, 13(11), 7561-7567 (2013-11-20)
Thin ZrO2/Al2O3 films that consisted of alternating monoclinic ZrO2 nanolayers and amorphous Al2O3 nanolayers were deposited on a tool steel substrate using Zr and Al cathodes in a cathodic arc plasma deposition system, and then oxidized at 600-900 degrees C...
Robert A Yokel
Journal of Alzheimer's disease : JAD, 10(2-3), 223-253 (2006-11-23)
The etiology of many neurodegenerative diseases has been only partly attributed to acquired traits, suggesting environmental factors may also contribute. Metal dyshomeostasis causes or has been implicated in many neurodegenerative diseases. Metal flux across the blood-brain barrier (the primary route...
V Calabrese et al.
Neurochemical research, 28(9), 1321-1328 (2003-08-27)
Recent studies suggest that NO and its reactive derivative peroxynitrite are implicated in the pathogenesis of multiple sclerosis (MS). Patients dying with MS demonstrate increased astrocytic inducible nitric oxide synthase activity, as well as increased levels of iNOS mRNA. Peroxynitrite...
P A LeWitt et al.
Neurology, 42(11), 2111-2117 (1992-11-01)
We used two analytic methods (a multichannel coulometric electrode array with high-performance liquid chromatography, and gas chromatography-mass spectrophotometry) to measure CSF dopamine (DA) and its metabolites in mildly affected, unmedicated subjects with Parkinson's disease (PD). The mean (+/- SD) concentration...
Steffen Rausch et al.
Urology, 85(1), 182-188 (2014-12-23)
To evaluate complications and functional outcome and to identify patient-associated risk factors, we analyzed consecutive patients undergoing thulium:yttrium-aluminum-garnet laser enucleation of the prostate (ThuLEP) in our department. A total of 234 patients were prospectively analyzed. Preoperative data, postoperative complications, and...
Giovanni Forte et al.
Annali dell'Istituto superiore di sanita, 41(2), 213-216 (2005-10-26)
Although some studies suggested a link between exposure to trace elements and development of multiple sclerosis (MS), clear information on their role in the aetiology of MS is still lacking. In this study the concentrations of Al, Ba, Be, Bi...
Masahiro Kawahara
Journal of Alzheimer's disease : JAD, 8(2), 171-182 (2005-11-26)
Aluminum is environmentally abundant, but not an essential element. Aluminum has been associated with several neurodegenerative diseases, such as dialysis encephalopathy, amyotrophic lateral sclerosis and Parkinsonism dementia in the Kii peninsula and Guam, and in particular, Alzheimer's disease. Although this...
R H Kadam et al.
Journal of nanoscience and nanotechnology, 14(6), 4101-4107 (2014-04-18)
Ferrite samples with a chemical formula Co0.5Ni0.5Al(x)Fe(2-x)O4 (where x = 0.0, 0.25, 0.5, 0.75 and 1.0) were synthesized by sol-gel auto-combustion method. The synthesized samples were annealed at 600 degrees C for 4 h. An analysis of X-ray diffraction (XRD)...

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