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Showing 1-12 of 12 results for "m01010-hh" within Papers
Yoshitaka Kawanishi et al.
Arthritis research & therapy, 16(6), 488-488 (2014-11-29)
The important functions of the meniscus are shock absorption, passive stabilization and load transmission of the knee. Because of the avascularity of two-thirds of the meniscal center region, the treatment of tears in this area is hard. Recently, microRNAs have
Sajal Shrivastava et al.
Nanoscale, 7(46), 19663-19672 (2015-11-11)
Although real-time label-free fluorescent aptasensors based on nanomaterials are increasingly recognized as a useful strategy for the detection of target biomolecules with high fidelity, the lack of an imaging-based quantitative measurement platform limits their implementation with biological samples. Here we
Martin G Belinsky et al.
BMC cancer, 15, 887-887 (2015-11-12)
Approximately 10-15 % of gastrointestinal stromal tumors (GISTs) lack gain of function mutations in the KIT and platelet-derived growth factor receptor alpha (PDGFRA) genes. An alternate mechanism of oncogenesis through loss of function of the succinate-dehydrogenase (SDH) enzyme complex has
Satoshi Kambayashi et al.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 79(3), 201-209 (2015-07-02)
The DNA repair protein O (6)-methylguanine-DNA methyltransferase (MGMT) causes resistance to nitrosoureas in various human cancers. In this study, we analyzed the correlation between canine lymphomas and MGMT in vitro. Two of five canine lymphoma cell lines required higher concentrations
Shoji Saito et al.
Cytotherapy, 16(9), 1257-1269 (2014-08-12)
To develop a treatment option for Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+)ALL) resistant to tyrosine kinase inhibitors (TKIs), we evaluated the anti-leukemic activity of T cells non-virally engineered to express a CD19-specific chimeric antigen receptor (CAR). A CD19.CAR gene was
Amanda S Bruegl et al.
Cancer prevention research (Philadelphia, Pa.), 7(7), 686-697 (2014-04-29)
Clinical criteria, primarily young age of cancer onset and family history of signature cancers, have been developed to identify individuals at elevated risk for Lynch syndrome with the goals of early identification and cancer prevention. In 2007, the Society of
Li Pan et al.
Clinica chimica acta; international journal of clinical chemistry, 450, 304-309 (2015-09-08)
Carcinoembryonic antigen (CEA) as one of the most widely used tumor markers is used in the clinical diagnosis of colorectal, pancreatic, gastric, and cervical carcinomas. We developed an aptamer-based microchip electrophoresis assay technique for assaying CEA in human serum for
Anna J Henningsson et al.
BMC microbiology, 15, 153-153 (2015-08-02)
A TaqMan real-time PCR assay targeting the Anaplasma citrate synthase gene, gltA, was developed and used for detection of Anaplasma phagocytophilum in 765 Ixodes ricinus ticks collected from dogs and cats in northern Norway (n = 669) and Telemark county in southern
C L Bethea et al.
Molecular psychiatry, 20(12), 1565-1578 (2015-01-21)
Depression often accompanies the perimenopausal transition and it often precedes overt symptomology in common neurodegenerative diseases (NDDs, such as Alzheimer's, Parkinson's, Huntington, amyotrophic lateral sclerosis). Serotonin dysfunction is frequently found in the different etiologies of depression. We have shown that
Annelies Stevaert et al.
Molecular pharmacology, 87(2), 323-337 (2014-12-06)
The influenza virus PA endonuclease, which cleaves capped cellular pre-mRNAs to prime viral mRNA synthesis, is a promising target for novel anti-influenza virus therapeutics. The catalytic center of this enzyme resides in the N-terminal part of PA (PA-Nter) and contains
Chiaki Taira et al.
Clinica chimica acta; international journal of clinical chemistry, 445, 101-106 (2015-03-24)
Chimerism analysis is important for the evaluation of engraftment and predicting relapse following hematopoietic stem cell transplantation (HSCT). We developed a chimerism analysis for single nucleotide polymorphisms (SNPs), including rapid screening of the discriminable donor/recipient alleles using droplet allele-specific PCR
Hiroaki Tachibana et al.
Biosensors & bioelectronics, 74, 725-730 (2015-07-27)
Polymerase chain reaction (PCR)-based genetic testing has become a routine part of clinical diagnoses and food testing. In these fields, rapid, easy-to-use, and cost-efficient PCR chips are expected to be appeared for providing such testing on-site. In this study, a
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