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Showing 1-30 of 95 results for "M2634" within Papers
Rosa Amarilis Rodríguez-Frómeta et al.
Applied microbiology and biotechnology, 97(7), 3063-3072 (2012-10-12)
Commercial interest in microbial lipids is increasing due to their potential use as feedstock for biodiesel production. The supply of NADPH generated by malic enzyme (ME; NADP+-dependent; EC 1.1.1.40) has been postulated as being the rate-limiting step for fatty acid
G Harish et al.
Neurochemical research, 38(1), 186-200 (2012-10-17)
Altered redox dynamics contribute to physiological aging and Parkinson's disease (PD). This is reflected in the substantia nigra (SN) of PD patients as lowered antioxidant levels and elevated oxidative damage. Contrary to this observation, we previously reported that non-SN regions
Chao Wang et al.
Biochimica et biophysica acta, 1834(10), 1969-1975 (2013-07-09)
Rhodotorula taiwanensis RS1 is a high-aluminum (Al)-tolerant yeast that can survive in Al concentrations up to 200mM. The mechanisms for the high Al tolerance of R. taiwanensis RS1 are not well understood. To investigate the molecular mechanisms underlying Al tolerance
Clelia Muccio et al.
The protein journal, 31(8), 667-673 (2012-09-12)
A novel malate dehydrogenase (MDH; EC 3.1.1.1.37), hereafter MDHCs, from Ceratonia siliqua seeds, commonly known as Carob tree, was purified by using ammonium sulphate precipitation, ion exchange chromatography on SteamLine SP and gel-filtration. The molecular mass of the native protein
Teresa Z Rzezniczak et al.
G3 (Bethesda, Md.), 2(12), 1613-1623 (2013-01-01)
Interactions across biological networks are often quantified under a single set of conditions; however, cellular behaviors are dynamic and interactions can be expected to change in response to molecular context and environment. To determine the consistency of network interactions, we
Frederik M Meyer et al.
FEMS microbiology letters, 339(1), 17-22 (2012-11-10)
The Gram-positive soil bacterium Bacillus subtilis uses glucose and malate as the preferred carbon sources. In the presence of either glucose or malate, the expression of genes and operons for the utilization of secondary carbon sources is subject to carbon
Thomas R Burkard et al.
BMC systems biology, 5, 17-17 (2011-01-29)
On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitously expressed in all human cells. Composition and properties
Cindy D Crocker et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 166(2), 141-147 (2013-08-27)
The African cichlid, Pseudocrenilabrus multicolor victoriae is a eurytopic fish that exhibits high levels of developmental plasticity in response to dissolved oxygen availability. In this study, F1 offspring from three sites in the Mpanga River drainage of Western Uganda characterized
Mary-Rus Martínez-Cuenca et al.
Tree physiology, 33(3), 320-329 (2013-03-07)
The effects of iron (Fe) deficiency on the low-molecular-weight organic acid (LMWOA) metabolism have been investigated in Carrizo citrange (CC) [Citrus sinensis (L.) Osb. × Poncirus trifoliata (L.) Raf.] roots. Major LMWOAs found in roots, xylem sap and root exudates were citrate
Purification and properties of Drosophila malate dehydrogenases.
M S McReynolds et al.
Biochimica et biophysica acta, 198(2), 165-175 (1970-02-11)
Comparative molluscicidal action of extract of Ginko biloba sarcotesta, arecoline and niclosamide on snail hosts of Schistosoma japonicum
Chen, S., et al.
Pesticide Biochemistry and Physiology, 89, 237-241 (2007)
J C Venter et al.
Science (New York, N.Y.), 291(5507), 1304-1351 (2001-02-22)
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months from 27,271,853 high-quality sequence reads (5.11-fold coverage
Eun Young Jung et al.
Annals of nutrition & metabolism, 61(2), 89-94 (2012-08-15)
We observed whether the anti-obesity activity of yeast hydrolysate (YH) was due to the alteration of lipid-regulating enzyme activities. Male ICR mice were divided into four groups: a normal diet group (ND; 4.2% fat), a high-fat diet group (HF; 27.7%
Yumi Morimoto et al.
Journal of bioscience and bioengineering, 117(2), 147-152 (2013-08-13)
The directed evolution of the thermotolerant NADP(H)-dependent malic enzyme from Thermococcus kodakarensis was conducted to alter the cofactor preference of the enzyme from NADP(H) to NAD(H). The construction and screening of two generations of mutant libraries led to the isolation
Qiong Liu et al.
The Prostate, 73(10), 1028-1037 (2013-02-08)
Resistance to chemotherapy represents a significant obstacle in prostate cancer therapeutics. Novel mechanistic understandings in cancer cell chemotherapeutic sensitivity and resistance can optimize treatment and improve patient outcome. Molecular alterations in the metabolic pathways are associated with cancer development; however
X M Men et al.
Animal : an international journal of animal bioscience, 7(9), 1486-1492 (2013-06-15)
The objective of this study is to investigate the age-related changes of and the effects of dietary conjugated linoleic acid (CLA) on muscle-fibre types in commercial pigs. We divided 25 crossbred male pigs into five age groups (7, 30, 60
Ahmed Al-Dwairi et al.
PloS one, 7(10), e46716-e46716 (2012-10-12)
Obesity and associated hormonal disturbances are risk factors for colon cancer. Cytosolic Malic Enzyme (ME1) generates NADPH used for lipogenesis in gastrointestinal (GI), liver and adipose tissues. We have reported that inclusion of soy protein isolate (SPI) in the diet
Kwang Suk Lim et al.
Journal of controlled release : official journal of the Controlled Release Society, 171(2), 193-200 (2013-07-23)
Protein transduction domains (PTDs), also known as cell-penetrating peptides (CPPs), have been developed as effective systems for delivering bio-active cargos such as proteins, genes and particles. Further improvements on cell-specific targeting, intracellular organelle targeting and intracellular retention are still necessary
Allan E Strand et al.
PloS one, 7(9), e45138-e45138 (2012-10-11)
A common geographical pattern of genetic variation is the one-dimensional cline. Clines may be maintained by diversifying selection across a geographical gradient but can also reflect historical processes such as allopatry followed by secondary contact. To identify loci that may
Yan He et al.
PloS one, 8(3), e57118-e57118 (2013-03-28)
Maintaining metabolic homeostasis is critical for plant growth and development. Here we report proteome and metabolome changes when the metabolic homeostasis is perturbed due to gene-dosage dependent mutation of Arabidopsis isopropylmalate dehydrogenases (IPMDHs). By integrating complementary quantitative proteomics and metabolomics
Maaike Van Trimpont et al.
Haematologica (2022-08-19)
Asparagine is a non-essential amino acid since it can either be taken up via the diet or synthesized by asparagine synthetase (ASNS). Acute lymphoblastic leukemia (ALL) cells do not or minimally express ASNS which makes them completely dependent on extracellular
Kevork Hagopian et al.
Life sciences, 93(24), 941-948 (2013-10-22)
The purpose of the study was to establish if enzyme activities from key metabolic pathways and levels of markers of oxidative damage to proteins and lipids differed between distinct liver mitochondrial sub-populations, and which specific sub-populations contributed to these differences.
Xiaoting Ye et al.
Microbial cell factories, 11, 120-120 (2012-09-07)
The integration of biotechnology into chemical manufacturing has been recognized as a key technology to build a sustainable society. However, the practical applications of biocatalytic chemical conversions are often restricted due to their complexities involving the unpredictability of product yield
Eun Young Kim et al.
Biochemical and biophysical research communications, 441(1), 77-82 (2013-10-19)
Previously, we identified proteins showing a differential acetylation pattern during adipogenic differentiation. Here, we examined the role of malate dehydrogenase 2 (MDH2) acetylation in the adipogenesis of 3T3-L1 preadipocytes. The acetylation level of MDH2 showed a dramatic increase during adipogenesis.
I A Hassan et al.
Parasite immunology, 36(12), 674-683 (2014-09-23)
Toxoplasma gondii Malate dehydrogenase (TgMDH) plays an important role as part of the energy production cycle. In this investigation, immunological changes and protection efficiency of this protein delivered as a DNA vaccine have been evaluated. Mice were intramuscularly immunized with
Eva E R Philipp et al.
PloS one, 7(9), e44621-e44621 (2012-10-03)
The bivalve Arctica islandica is extremely long lived (>400 years) and can tolerate long periods of hypoxia and anoxia. European populations differ in maximum life spans (MLSP) from 40 years in the Baltic to >400 years around Iceland. Characteristic behavior
S Cyrus Khojasteh et al.
Chemical research in toxicology, 25(11), 2301-2309 (2012-10-31)
Pulegone is the major constituent of pennyroyal oil, a folkloric abortifacient that is associated with hepatotoxicity and, in severe cases, death. Cytochrome P450-mediated oxidation of pulegone generates menthofuran, which is further oxidized to form electrophilic reactive intermediates, menthofuran epoxide and
Morgan Kullberg et al.
Molecular biology and evolution, 23(8), 1493-1503 (2006-06-06)
The molecular relationship of placental mammals has attracted great interest in recent years. However, 2 crucial and conflicting hypotheses remain, one with respect to the position of the root of the eutherian tree and the other the relationship between the
Jesper V Olsen et al.
Science signaling, 3(104), ra3-ra3 (2010-01-14)
Eukaryotic cells replicate by a complex series of evolutionarily conserved events that are tightly regulated at defined stages of the cell division cycle. Progression through this cycle involves a large number of dedicated protein complexes and signaling pathways, and deregulation
D C Simcock et al.
Experimental parasitology, 132(2), 267-273 (2012-08-21)
Nematodes which have adapted to an anaerobic lifestyle in their adult stages oxidise phosphoenolpyruvate (PEP) to oxaloacetate rather than pyruvate as the final product of glycolysis. This adaptation involves selective expression of the enzyme phosphoenolpyruvate carboxykinase (PEPCK), instead of pyruvate
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