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Showing 1-30 of 472 results for "m3183" within Papers
Katelyn T Gause et al.
ACS nano, 9(3), 2433-2444 (2015-02-26)
The development of subunit antigen delivery formulations has become an important research endeavor, especially in cases where a whole cell vaccine approach has significant biosafety issues. Particle-based systems have shown particular efficacy due to their inherent immunogenicity. In some cases
David L Jakeman et al.
Journal of industrial microbiology & biotechnology, 33(9), 767-772 (2006-03-29)
The jadomycins are a unique family of benzoxazolophenanthridine antibiotics produced by Streptomyces venezuelae ISP5230 following heat or ethanol shock or phage infection. We have modified the culture conditions by altering the carbon source, buffer, inoculum size, and timing of ethanol
Claine L Snow et al.
Journal of inorganic biochemistry, 105(7), 972-977 (2011-05-13)
The buffer used during horse spleen ferritin iron loading significantly influences the mineralization process and the quantity of iron deposited in ferritin. Ferritin iron loading in imidazole shows a rapid hyperbolic curve in contrast to iron loading in 3-(N-morpholino)propanesulfonic acid
Go Atsumi et al.
The Journal of general virology, 96(Pt 2), 431-439 (2014-10-30)
In this study, we identified a novel virus from gentian (Gentiana triflora) that causes ring-spots on ovaries. Furthermore, the virus causes unusual symptoms, ring-spots that appear specifically on the outer surface of the ovarian wall after pollination. Pollen grains carrying
Vibhuti Vyas et al.
The American journal of pathology, 185(3), 862-869 (2015-01-13)
Premature delivery occurs in 12% of all births, and accounts for nearly half of long-term neurological morbidity, and 60% to 80% of perinatal mortality. Despite advances in obstetrics and neonatology, the rate of premature delivery has increased approximately 12% since
Christopher H Douse et al.
ChemMedChem, 10(1), 134-143 (2014-11-05)
Motility is a vital feature of the complex life cycle of Plasmodium falciparum, the apicomplexan parasite that causes human malaria. Processes such as host cell invasion are thought to be powered by a conserved actomyosin motor (containing myosin A or myoA)
Alyssa K Van Dreumel et al.
Journal of clinical microbiology, 53(6), 1797-1805 (2015-03-20)
An amino acid consensus sequence for the seven serotypes of foot-and-mouth disease virus (FMDV) nonstructural protein 3B, including all three contiguous repeats, and its use in the development of a pan-serotype diagnostic test for all seven FMDV serotypes are described.
Helena Kaihola et al.
PloS one, 10(1), e0116459-e0116459 (2015-01-23)
Depressive symptoms during pregnancy are common and may have impact on the developing child. Selective serotonin reuptake inhibitors (SSRIs) are the most prescribed antidepressant treatment, but unfortunately, these treatments can also negatively affect the behavioral development and health of a
Don L Tucker et al.
Journal of bacteriology, 184(23), 6551-6558 (2002-11-12)
Escherichia coli MG1655 acid-inducible genes were identified by whole-genome expression profiling. Cultures were grown to the mid-logarithmic phase on acidified glucose minimal medium, conditions that induce glutamate-dependent acid resistance (AR), while the other AR systems are either repressed or not
Changgui Li et al.
Human vaccines & immunotherapeutics, 11(6), 1351-1356 (2015-05-15)
The outbreak of human infections of a novel avian influenza virus A (H7N9) prompted the development of the vaccines against this virus. Like all types of influenza vaccines, H7N9 vaccine must be tested for its potency prior to being used
Shewit Kalayou et al.
Cell biology and toxicology, 30(6), 361-376 (2014-11-25)
The mycotoxin alternariol (AOH) is an important contaminant of fruits and cereal products. The current study sought to address the effect of a non-toxic AOH concentration on the proteome of the steroidogenic H295R cell model. Quantitative proteomics based on stable
Constantine Chrysostomou et al.
ACS chemical biology, 10(3), 875-882 (2014-12-18)
Microbial arsenate resistance is known to be conferred by specialized oxidoreductase enzymes termed arsenate reductases. We carried out a genetic selection on media supplemented with sodium arsenate for multicopy genes that can confer growth to E. coli mutant cells lacking
Djalila Mekahli et al.
Pflugers Archiv : European journal of physiology, 466(8), 1591-1604 (2013-11-07)
Autosomal dominant polycystic kidney disease (ADPKD) is caused by loss-of-function mutations in either PKD1 or PKD2 genes, which encode polycystin-1 (TRPP1) and polycystin-2 (TRPP2), respectively. Increased activity of the mammalian target of rapamycin (mTOR) pathway has been shown in PKD1
Jérémy A Ferreira Barbosa et al.
Virology journal, 12, 188-188 (2015-11-19)
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most important pathogens in the swine industry and causes important economic losses. No effective antiviral drugs against it are commercially available. We recently reported that the culture supernatant of
Fang Zhang et al.
PloS one, 10(7), e0132948-e0132948 (2015-07-22)
Bacteria predominantly reside in microbial communities known as biofilms, where cells are encapsulated and protected by the extracellular matrix (ECM). While all biofilm cells benefit from the ECM, only a subgroup of cells carries the burden of producing this public
Tivadar Orban et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(11), 4579-4588 (2015-07-19)
Age-related macular degeneration (AMD) is a neurodegenerative disease that causes adult-onset blindness. There are 2 forms of this progressive disease: wet and dry. Currently there is no cure for AMD, but several treatment options have started to emerge making early
María José Varela Liste et al.
Molecular pharmacology, 87(6), 936-953 (2015-03-15)
G protein-coupled receptors, including the M3 muscarinic acetylcholine receptor, can form homo-oligomers. However, the basis of these interactions and the overall organizational structure of such oligomers are poorly understood. Combinations of site-directed mutagenesis and homogenous time-resolved fluorescence resonance energy transfer
Lawrence Mok et al.
The Journal of general virology, 96(Pt 7), 1787-1794 (2015-03-10)
In recent years, bats have been identified as a natural reservoir for a diverse range of viruses. Nelson Bay orthoreovirus (NBV) was first isolated from the heart blood of a fruit bat (Pteropus poliocephalus) in 1968. While the pathogenesis of
Seyedeh Mahdieh Hashemi et al.
Bioorganic & medicinal chemistry, 23(7), 1481-1491 (2015-03-06)
In order to find new azole antifungals, we have recently designed a series of triazole alcohols in which one of the 1,2,4-triazol-1-yl group in fluconazole structure has been replaced with 4-amino-5-aryl-3-mercapto-1,2,4-triazole motif. In this paper, we focused on the structural
Jingqi Chen et al.
Microbial cell factories, 14, 92-92 (2015-06-27)
Secretory expression of valuable proteins by B. subtilis and its related species has attracted intensive work over the past three decades. Although very high yields can be achieved with homologous proteins, production of heterologous proteins by B. subtilis is unfortunately
Eduardo Padilla-Camberos et al.
BioMed research international, 2015, 837452-837452 (2015-06-17)
Cholesterol control is fundamental for prevention of cardiovascular disorders. In this work, the hypocholesterolemic activity of an aqueous Opuntia ficus-indica extract (AOE) was tested in triton-induced mice. The inhibitory activity on pancreatic lipase enzyme was evaluated in vitro by the
Ana Karina Rodrigues Abadio et al.
PloS one, 10(11), e0142926-e0142926 (2015-11-17)
The prevalence of invasive fungal infections worldwide has increased in the last decades. The development of specific drugs targeting pathogenic fungi without producing collateral damage to mammalian cells is a daunting pharmacological challenge. Indeed, many of the toxicities and drug
Priyadarsini Kumar et al.
PloS one, 10(8), e0135089-e0135089 (2015-08-13)
Trophoblast differentiation during early placental development is critical for successful pregnancy and aberrant differentiation causes preeclampsia and early pregnancy loss. During the first trimester, cytotrophoblasts are exposed to low oxygen tension (equivalent to~2%-3% O2) and differentiation proceeds along an extravillous
Ashraf Ahmad et al.
Bioscience, biotechnology, and biochemistry, 71(8), 1970-1978 (2007-08-11)
Real-time PCR is a potent technique for nucleic acid quantification for research and diagnostic purposes, the wide dynamic range being one of the advantages over other techniques like the microarray. Several additives and enhancers have been studied to expand the
Jukka Pätsi et al.
Mitochondrion, 22, 23-30 (2015-03-10)
Effects of Complex I mutations were studied by modeling in NuoH, NuoJ or NuoK subunits of Escherichia coli NDH-1 by simultaneous optical monitoring of deamino-NADH oxidation and proton translocation and fitting to the data a model equation of transmembrane proton
Timothy A Vickers et al.
PloS one, 9(10), e108625-e108625 (2014-10-10)
Antisense oligonucleotides (ASOs) are most commonly designed to reduce targeted RNA via RNase H1-dependent degradation. In this paper we demonstrate that cellular proteins can compete for sites targeted by RNase H1-dependent ASOs. We further show that some ASOs designed to
Devashish Rath et al.
Nucleic acids research, 43(1), 237-246 (2014-12-02)
Methods that permit controlled changes in the expression of genes are important tools for biological and medical research, and for biotechnological applications. Conventional methods are directed at individually changing each gene, its regulatory elements or its mRNA's translation rate. We
Karen Vernau et al.
Brain pathology (Zurich, Switzerland), 25(4), 441-453 (2014-08-15)
Alaskan Husky encephalopathy (AHE(1) ) is a fatal brain disease associated with a mutation in SLC19A3.1 (c.624insTTGC, c.625C>A). This gene encodes for a thiamine transporter 2 with a predominately (CNS) central nervous system distribution. Considering that brain is particularly vulnerable
Elleke F Bosma et al.
Microbial cell factories, 14, 99-99 (2015-07-08)
Microbial conversion of biomass to fuels or chemicals is an attractive alternative for fossil-based fuels and chemicals. Thermophilic microorganisms have several operational advantages as a production host over mesophilic organisms, such as low cooling costs, reduced contamination risks and a
Sandy G Y Szeto et al.
Experimental cell research, 330(2), 248-266 (2014-12-03)
In cell culture, many adherent mammalian cells undergo substantial actin cytoskeleton rearrangement prior to mitosis as they detach from the extracellular matrix and become spherical. At the end of mitosis, the actin cytoskeleton is required for cytokinesis and the reassembly
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