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Keyword:'minor'
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minor

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NR4A3
nuclear receptor subfamily 4, group A, member 3
Synonyms:
CHN, CSMF, MINOR, NOR1, TEC
Species:
Human NR4A3 (8013), Mouse Nr4a3 (18124), Rat Nr4a3 (58853), Zebrafish nr4a3 (548604), domestic cat NR4A3 (101094302), cow NR4A3 (528877), Horse NR4A3 (100063566), dog NR4A3 (100684628), chicken NR4A3 (420996), domestic guinea pig Nr4a3 (100715800), naked mole-rat Nr4a3 (101715548), Domestic Rabbit NR4A3 (100344785), sheep NR4A3 (101122759)
Summary:
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010
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HM13
histocompatibility (minor) 13
Synonyms:
H13, IMP1, IMPAS, IMPAS-1, MSTP086, PSENL3, PSL3, SPP, SPPL1, dJ324O17.1
Species:
Human HM13 (81502), Rat Hm13 (311545), sheep HM13 (101111384), Domestic Rabbit HM13 (100348554), domestic guinea pig Hm13 (100712676), naked mole-rat Hm13 (101715311), Zebrafish hm13 (259190), chicken HM13 (100859573), domestic cat HM13 (101097309), cow HM13 (512534), Horse HM13 (100053502), dog HM13 (608355)
Summary:
The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008
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HMHB1
histocompatibility (minor) HB-1
Synonyms:
HB-1, HLA-HB1
Species:
Human HMHB1 (57824)
Summary:
This gene encodes one of the minor histocompatibility antigens, which play an important role in the induction of cytotoxic T lymphocyte (CTL) reactivity against leukemia after human histocompatibility leukocyte antigen (HLA)-identical allogeneic bone marrow transplantation (BMT). This gene is only expressed in B cell acute lymphoblastic leukemia cells and Epstein-Barr virus-transformed B cells. The translation of this mRNA initiates at a non-AUG (CUG) codon. [provided by RefSeq, Jul 2008
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HMHA1
histocompatibility (minor) HA-1
Synonyms:
ARHGAP45, HA-1, HLA-HA1
Species:
Human HMHA1 (23526), Mouse Hmha1 (70719), Rat Hmha1 (314618), Zebrafish hmha1 (555849), chicken HMHA1 (420102), cow HMHA1 (512972), dog HMHA1 (612358), naked mole-rat Hmha1 (101709827), sheep HMHA1 (101112901)
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HMSD
histocompatibility (minor) serpin domain containing
Synonyms:
ACC-6, C18orf53, HSMD-v
Species:
Human HMSD (284293)
Summary:
This gene encodes a serpin-domain containing protein that may function as a serine protease inhibitor. This gene is primarily expressed in cells of myeloid lineage. A polymorphism in this gene may result in the expression a splice variant that encodes a minor histocompatibility antigen. [provided by RefSeq, Oct 2010
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Species:
Rat LOC100134871 (100134871)
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Mouse Hbb-b2 (15130)
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Species:
Mouse Hrs3 (110044)
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Mouse Bkm5 (107536)
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Human BKMA1 (7951)
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Mouse Bkm1 (12131)
Species:
Mouse Hrs2 (104324)
Synonyms:
HLA-HA2
Species:
Human D6S207E (7921)
Species:
Mouse Bkm6 (107548)
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Mouse Bkm2 (107534)
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Mouse Bkm3 (107535)
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Mouse Bkm4 (107547)
Species:
Mouse Hrs1 (108321), Thale Cress HRS1 (837890), Thale Cress HRS1 (823753)
NVL
nuclear VCP-like
Species:
Human NVL (4931), Mouse Nvl (67459), Rat Nvl (289323), Thale Cress NVL (837350), dog NVL (480117), cow NVL (532708), Horse NVL (100055652), domestic cat NVL (101101532), chicken NVL (421326), Zebrafish nvl (406805), sheep NVL (101108847), domestic guinea pig Nvl (100722919), naked mole-rat Nvl (101723576), Domestic Rabbit NVL (100355144)
Summary:
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. [provided by RefSeq, Aug 2011
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APOF
apolipoprotein F
Synonyms:
Apo-F, LTIP
Species:
Human APOF (319), Mouse Apof (103161), Rat Apof (500761), Zebrafish apof (793418), cow APOF (539595), domestic cat APOF (101086159), dog APOF (474405), naked mole-rat Apof (101719803), domestic guinea pig Apof (100719444), sheep APOF (101102138)
Summary:
The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with lipoproteins and may be involved in transport and/or esterification of cholesterol. [provided by RefSeq, Jul 2008
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ASGR2
asialoglycoprotein receptor 2
Synonyms:
ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2
Species:
Human ASGR2 (433), Mouse Asgr2 (11890), Rat Asgr2 (29403), sheep ASGR2 (101115381), domestic guinea pig Asgr2 (100714463), naked mole-rat Asgr2 (101705711), domestic cat ASGR2 (101095292), cow ASGR2 (531519), dog ASGR2 (100687999)
Summary:
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011
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RNPC3
RNA-binding region (RNP1, RRM) containing 3
Synonyms:
RBM40, RNP, SNRNP65
Species:
Human RNPC3 (55599), Mouse Rnpc3 (67225), Rat Rnpc3 (691538), Zebrafish rnpc3 (565672), dog RNPC3 (490136), domestic cat RNPC3 (101092872), chicken RNPC3 (424458), cow RNPC3 (768060), sheep RNPC3 (101118319), naked mole-rat Rnpc3 (101703023), domestic guinea pig Rnpc3 (100723783)
Summary:
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008
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PDCD7
programmed cell death 7
Synonyms:
ES18, HES18
Species:
Human PDCD7 (10081), Mouse Pdcd7 (50996), Rat Pdcd7 (363082), cow PDCD7 (784973), sheep PDCD7 (101110945), domestic guinea pig Pdcd7 (100714705), naked mole-rat Pdcd7 (101724702), Zebrafish pdcd7 (445020), chicken PDCD7 (415528), domestic cat PDCD7 (101096237), dog PDCD7 (612964)
Summary:
This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010
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KDM5D
lysine (K)-specific demethylase 5D
Synonyms:
HY, HYA, JARID1D, SMCY
Species:
Human KDM5D (8284), Mouse Kdm5d (20592), Rat Kdm5d (100312983), dog KDM5D (100134936), Horse KDM5D (100034191), cow KDM5D (281491)
Summary:
This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009
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DPYS
dihydropyrimidinase
Synonyms:
DHP, DHPase
Species:
Human DPYS (1807), Mouse Dpys (64705), Rat Dpys (65135), Zebrafish dpys (100144569), cow DPYS (509241), domestic cat DPYS (101085020), dog DPYS (475067), chicken DPYS (420266), naked mole-rat Dpys (101723598), domestic guinea pig Dpys (100717795), sheep DPYS (101102070)
Summary:
Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria. [provided by RefSeq, Jul 2008
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STT3B
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
Synonyms:
SIMP, STT3-B
Species:
Human STT3B (201595), Mouse Stt3b (68292), Rat Stt3b (363160), domestic guinea pig Stt3b (100735712), naked mole-rat Stt3b (101708251), cow STT3B (504474), sheep STT3B (101111133), Thale Cress STT3B (840312), chicken STT3B (428444), domestic cat STT3B (101092883), dog STT3B (485628), Zebrafish stt3b (323918)
Summary:
The SIMP protein contains a highly immunogenic minor histocompatibility antigen epitope of 9 amino acids, B6(dom1). Like ITM1 (MIM 601134), SIMP is homologous to yeast STT3, an oligosaccharyltransferase essential for cell proliferation (McBride et al., 2002 [PubMed 12439619
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UPK3B
uroplakin 3B
Synonyms:
P35, UP3B, UPIIIB
Species:
Human UPK3B (80761), Mouse Upk3b (100647), Rat Upk3b (360790), cow UPK3B (282115), sheep UPK3B (101116795), naked mole-rat Upk3b (101720237), domestic guinea pig Upk3b (100730184), chicken UPK3B (101668319), chicken UPK3B (101749942), dog UPK3B (607577), domestic cat UPK3B (101083641)
Summary:
UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744
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UTY
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
Synonyms:
UTY1
Species:
Human UTY (7404), Mouse Uty (22290), dog UTY (100500941), cow UTY (100271759)
Summary:
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2012
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TOX3
TOX high mobility group box family member 3
Synonyms:
CAGF9, TNRC9
Species:
Human TOX3 (27324), Mouse Tox3 (244579), Rat Tox3 (291908), Zebrafish tox3 (555286), Horse TOX3 (100059910), domestic cat TOX3 (101097364), dog TOX3 (487281), chicken TOX3 (415724), cow TOX3 (539135), sheep TOX3 (101117611), domestic guinea pig Tox3 (100733069), naked mole-rat Tox3 (101704440)
Summary:
The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009
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NTF4
neurotrophin 4
Synonyms:
GLC10, GLC1O, NT-4, NT-4/5, NT-5, NT4, NT5, NTF5
Species:
Human NTF4 (4909), Rat Ntf4 (25730), sheep NTF4 (101104334), domestic guinea pig Ntf4 (100729889), cow NTF4 (506660), domestic cat NTF4 (101100428), dog NTF4 (611987)
Summary:
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008
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