Showing 1-30 of 44 results for "N2001"
H S Bawaskar et al.
Tropical doctor, 44(2), 82-85 (2014-02-20)
Between January 2005 and August 2011 141 victims of krait bite poisoning were admitted to the general hospital at Mahad. Clinical signs and symptoms preceding the development of neuroparalysis were analyzed. Fifty-six percent of patients were male. A total of...
Alex Menys et al.
Radiology, 269(2), 443-450 (2013-06-27)
To assess the repeatability in human volunteers of software-quantified small bowel motility captured with magnetic resonance (MR) imaging and to test the ability to detect changes in motility induced by pharmacologic agents. The study was approved by the Royal Free...
Lucia Manni et al.
Integrative and comparative biology, 58(2), 317-328 (2018-06-07)
Tunicates, the sister group of vertebrates, possess a mechanoreceptor organ, the coronal organ, which is considered the best candidate to address the controversial issue of vertebrate hair cell evolution. The organ, located at the base of the oral siphon, controls...
Michael Benatar et al.
The Cochrane database of systematic reviews, 12, CD005081-CD005081 (2012-12-14)
Approximately 50% of people with myasthenia gravis present with purely ocular symptoms, so called ocular myasthenia. Of these between 50% to 60% develop generalized disease, most within two years. Their management is controversial. This is an update of a review...
A reply.
G Geldner et al.
Anaesthesia, 68(3), 307-308 (2013-02-07)
Sara Rodrigues et al.
Drug and chemical toxicology, 38(2), 126-132 (2014-05-23)
In recent decades, scientific research about the effects of anthropogenic xenobiotics on non-target organisms has increased. Among the likely effects, some studies reported the evaluation of biochemical and morphological changes in specific tissues or organs of fishes, such as gills...
Anesthesiology in the era of drug shortages: use of a succinylcholine infusion for a laparoscopic sigmoid colectomy due to a shortage of neostigmine.
Stephen M McHugh et al.
Journal of clinical anesthesia, 25(1), 79-81 (2012-12-19)
Jorge E Nieto et al.
American journal of veterinary research, 74(4), 579-588 (2013-03-28)
To determine the response to neostigmine of the contractile activity of the jejunum and pelvic flexure and the effects of a continuous rate infusion (CRI) of neostigmine in horses. 7 adult horses and tissue from 12 adult horses. A CRI...
Shan Jin et al.
Journal of biomolecular screening, 18(1), 108-115 (2012-09-11)
Organophosphates are a class of highly toxic chemicals that includes many pesticides and chemical weapons. Exposure to organophosphates, either through accidents or acts of terrorism, poses a significant risk to human health and safety. Existing antidotes, in use for over...
Mehmet Koca et al.
Chemical & pharmaceutical bulletin, 63(3), 210-217 (2015-03-12)
A novel series of meta-substituted ethanediamide and 2-butenediamide derivatives were synthesized and tested for their ability to inhibit electric eel acetylcholinesterase (AChE) and equine serum butyrylcholinesterase (BuChE). The synthesized compounds were evaluated against ChE enzymes using the colorimetric method described...
Ute Burkhardt et al.
Neuroscience letters, 572, 48-52 (2014-05-13)
The phospholipases D (PLD1 and 2) are signaling enzymes that catalyze the hydrolysis of phosphatidylcholine to phosphatidic acid, a lipid second messenger involved in cell proliferation, and choline, a precursor of acetylcholine (ACh). In the present study, we investigated development...
Machika Moriya et al.
Masui. The Japanese journal of anesthesiology, 63(4), 418-422 (2014-05-03)
We experienced severe asthmatic crisis during general anesthesia in a 45-year-old man with IgG4-related disease, COPD and athma undergoing removal of submandibular gland. The ventilatiory failure was caused by the stimulation of the operation, sputum, and neostigmine. His serum IgG4...
Colonic perforation following neostigmine administration.
David Shi Hao Liu et al.
ANZ journal of surgery, 82(12), 951-952 (2012-11-29)
Babar Kayani et al.
International journal of surgery (London, England), 10(9), 453-457 (2012-09-19)
A best evidence topic was written according to a structured protocol. In [patients with acute colonic pseudo-obstruction] is [neostigmine] superior to [conservative treatment] with respect to [duration of symptoms and complications]. In total 51 papers were found using the reported...
Liza-Marie Johnson et al.
Journal of palliative medicine, 15(9), 1042-1046 (2012-09-06)
We present a case of severe refractory constipation in an adolescent oncology patient with widely metastatic clear cell osteosarcoma who was ultimately found to have Ogilvie syndrome, also known as acute colonic pseudo-obstruction (ACPO). Ogilvie syndrome is characterized by dilatation...
Victor B Tsirline et al.
American journal of surgery, 204(6), 849-855 (2012-10-02)
Colonic pseudo-obstruction in critically ill patients may lead to devastating colonic perforation. Neostigmine is often the first-line intervention, because colonoscopy is more invasive and labor intensive. A retrospective 10-year review at a tertiary medical center identified 100 patients with Ogilvie's...
Neostigmine reversal doesn't improve postoperative respiratory safety.
Matthew J Meyer et al.
BMJ (Clinical research ed.), 346, f1460-f1460 (2013-03-21)
Xiang Xu et al.
The Journal of biological chemistry, 285(24), 18139-18143 (2010-04-28)
Histone deacetylases (HDACs) are best known as transcription corepressors through deacetylating histone tails. Here we show that HDAC2 is also involved in cap-dependent mRNA translation by promoting sumoylation of eukaryotic translation initiation factor 4E (eIF4E), which is independent of its...
Zhenyu Wu et al.
Evidence-based complementary and alternative medicine : eCAM, 2016, 5616905-5616905 (2016-07-19)
This study was designed to investigate the effect of Aurantii fructus immaturus flavonoid (AFIF) on the contraction of isolated gastric smooth muscle in rats and explore its underlying mechanisms. Isolated antral longitudinal smooth muscle strip (ALSMS) and pyloric circular smooth...
Nadine Pinder et al.
Clinical chemistry and laboratory medicine, 53(8), 1259-1264 (2015-01-08)
Physostigmine, commonly used as an antidote in anticholinergic poisoning, is reported to have additional pharmacological effects, such as activation of the cholinergic anti-inflammatory pathway in sepsis models. Due to the narrow therapeutic range of physostigmine and its metabolite eseroline, however...
M O Akinwale et al.
African journal of medicine and medical sciences, 41(2), 231-237 (2012-11-29)
The spinal route of analgesia has consolidated its place as a major modality in the management of both acute and chronic pain. The search for ideal additives to local anaesthetic agents to prolong the analgesic effects poses a challenge to...
Tetsufumi Sato et al.
Masui. The Japanese journal of anesthesiology, 62(1), 19-26 (2013-02-26)
Anticholinesterase, such as neostigmine, was used to be a standard drug at the end of surgery for reversal of nondepolarizing neuromuscular block. Neostigmine decreases the metabolism of acetylcholine (ACh) at the neuromuscular junction and allows its concentration to increase and...
Sugammadex in a parturient with myotonic dystrophy.
P Stourac et al.
British journal of anaesthesia, 110(4), 657-658 (2013-03-20)
Gabriel Mak et al.
Tumori, 99(5), e225-e228 (2013-12-24)
Paralytic ileus is a recognised side effect of the oral agent capecitabine. We present this report on a patient with metastatic colorectal cancer who was treated with capecitabine and presented with persistent paralytic ileus which did not respond to standard...
Modified carbon paste sensor for the potentiometric determination of neostigmine bromide in pharmaceutical formulations, human plasma and urine
Khorshid, A F and Issa, Y M
Biosensors And Bioelectronics, 51, 143-149 (2014)
Comparing sugammadex and neostigmine reversal of neuromuscular blockade in laparoscopic surgery.
D Jain et al.
Anaesthesia, 68(3), 306-307 (2013-02-07)
Ai-Jun Liu et al.
CNS neuroscience & therapeutics, 18(11), 918-926 (2012-10-31)
Decreased baroreflex sensitivity is associated with poor outcome in many cardiovascular diseases including stroke, but the molecular mechanism underlying this relationship is unclear. This work was designed to test the hypothesis that acetylcholine (ACh) and α7 nicotinic ACh receptor (α7nAChR)...
Jessica Kåhlin et al.
Experimental physiology, 99(8), 1089-1098 (2014-06-03)
Studies on experimental animals established that the carotid bodies are sensory organs for detecting arterial blood O2 levels and that the ensuing chemosensory reflex is a major regulator of cardiorespiratory functions during hypoxia. However, little information is available on the...
Differentiation and induced sensorial alteration of the coronal organ in the asexual life of a tunicate
Manni L, et al.
Integrative and Comparative Biology, 58(2), 317-328 (2018)
Emilie Øberg et al.
Ugeskrift for laeger, 175(7), 428-432 (2013-02-14)
Neuromuscular blockers (NMBs) provide good conditions for endotracheal intubation and surgery. NMBs have been associated with higher morbidity and mortality, mainly due to post-operative residual neuromuscular block. This may become history with the advent of sugammadex - an antidote to...

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