Showing 1-16 of 16 results for "O601"
S-S Li et al.
European review for medical and pharmacological sciences, 23(9), 3940-3950 (2019-05-23)
The aim of the study was to investigate the endogenous metabolites of patients with psoriasis vulgaris which will be helpful for the diagnosis of the disease and to provide the evidence of pathogenesis and the formulation for the individualized dosage...
Pengchao Sun et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 86, 612-619 (2016-12-28)
Submicron emulsions (SEs) is an advanced formulation that possesses good biocompatibility, high loading of hydrophobic drugs, and good stability through autoclave sterilization. To enhance tumor targeting and tumor cell uptake, SEs could be modified with positive charge and targeting moieties....
Monika Zbucka-Kretowska et al.
Chemosphere, 203, 387-392 (2018-04-09)
Bisphenol A (BPA) is a synthetic chemical widely used in the industry, which may potentially evoke negative effects on human health, especially on reproductive processes and fetal development. BPA has been reported to act on estrogen, estrogen-related, androgen, thyroid hormone...
Bo Yuan et al.
Journal of food and drug analysis, 26(2), 751-760 (2018-03-24)
African indigenous vegetables (AIVs) because of their nutrient density have the unique potential to reduce micronutrient deficiencies in sub-Saharan Africa, yet some may also contain anti-nutritive compounds. Vegetable nightshades from Solanum americanum, Solanum nigrum, Solanum scabrum and Solanum villosum are...
Sachiko Yamamoto et al.
Biochimica et biophysica acta, 1861(1 Pt A), 3399-3405 (2016-09-07)
SERCA maintains intracellular Ca2+ homeostasis by sequestering cytosolic Ca2+ into SR/ER stores. Two primary fatty acid amides (PFAAs), oleamide (18:19-cis) and linoleamide (18:29,12-cis), induce an increase in intracellular Ca2+ levels, which might be caused by their inhibition of SERCA. Three...
Sachiko Yamamoto et al.
Biochemical and biophysical research communications, 477(2), 266-270 (2016-06-15)
To identify specific inhibitors of the human secretary pathway Ca(2+)-ATPase 2 (hSPCA2), a recombinant hSPCA2 was expressed in Saccharomyces cerevisiae, and purified by Co(2+)-chelating chromatography. The isolated hSPCA2 catalyzed ATP hydrolysis in the presence of Ca(2+) ions. The Ca(2+) dissociation...
Aljona Saleh et al.
Journal of pharmaceutical and biomedical analysis, 104, 1-11 (2014-12-03)
MTH1 is a protein that is required for cancer cell survival and is overexpressed in cancer cells. TH588 and TH287 are two new compounds that inhibit the MTH1 protein. The inhibitors were tested in pharmacokinetic studies on mice. A bioanalytical...
Mark Gelmont et al.
Polymers, 12(2) (2020-02-12)
In the view of many national and international human health and environmental regulations, polymeric flame retardants are sustainable products. In this work, a series of high molecular weight and polymeric brominated flame retardants are synthesized by the alkylation of aromatic...
Jazmín Osorio et al.
Journal of chromatography. A, 1599, 215-222 (2019-04-13)
The rapid growth of polymer technology in the field of food contact materials (FCMs) needs to be supported by continuous improvement in material testing, in order to ensure the safety of foodstuff. In this work, a range of different starch-based...
Kosuke Saito et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1055-1056, 20-28 (2017-04-26)
In this study, we delineated the importance of MS resolving power on the ion-peak quantification of lipids using an Orbitrap Fusion instrument and established a liquid chromatography-based, high-performance lipidomics platform. The ion-peak recognition of several lipids in human plasma, such...
Jidong Ru et al.
Scientific reports, 8(1), 13045-13045 (2018-08-31)
The main aim of this investigation was to promote the dyeing and level-dyeing effect of reactive dyes on cotton-fiber dyeing by encapsulating reactive dyes in liposomes as an alternative to sodium chloride. The results obtained indicated that liposomes, especially cationic...
Paula Vera et al.
Talanta, 188, 750-762 (2018-07-22)
Migration of non volatile compounds from twenty six PP films used as food contact materials has been studied in four simulants (ethanol 95% and 10%, acetic acid 3% and Tenax ®) and analyzed by UPLC-MS/QTOF. Seventy six compounds have been...
Ling Li et al.
Molecular cell, 80(3), 525-540 (2020-10-18)
Well-balanced and timed metabolism is essential for making a high-quality egg. However, the metabolic framework that supports oocyte development remains poorly understood. Here, we obtained the temporal metabolome profiles of mouse oocytes during in vivo maturation by isolating large number of...
Yong Guo et al.
Materials (Basel, Switzerland), 12(6) (2019-03-20)
The thermal performance of wood⁻plastic composites (WPCs) with different fiber, different fiber contents, and different lubricants were investigated in this paper. The results show that the thermal degradation temperature, melting temperature, crystallization temperature, crystallinity, and viscosity of WPCs with wood...
Fan C Wang et al.
Journal of cosmetic science, 68(2), 159-172 (2018-04-06)
A petroleum-free skin cream was developed using food-grade ingredients. The rheological and sensorial properties of this petroleum-free skin cream were compared to a commercially available petroleum-based skin cream. Specifically, large-amplitude oscillatory shear (LAOS) characterization of the two skin creams was...
Qi-Zhi Su et al.
Talanta, 202, 285-296 (2019-06-07)
Atmospheric pressure gas chromatography (APGC) coupled to quadrupole time-of-flight (QTOF) and electron ionization mass spectrometry together with commercial library search are two complementary techniques for non-target screening of volatile and semi-volatile compounds. Optimization was first conducted to achieve easier search...

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon


Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.