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New head louse repellent.
I Burgess
The British journal of dermatology, 128(3), 357-358 (1993-03-01)
Patricia Guerra-Diaz et al.
Analytical chemistry, 82(7), 2826-2835 (2010-03-09)
A preconcentration device that targets the volatile chemical signatures associated with illicit drugs and explosives (high and low) has been designed to fit in the inlet of an ion mobility spectrometer (IMS). This is the first reporting of a fast...
The inhibition of rat nasal cytochrome P-450-dependent mono-oxygenase by the essence heliotropin (piperonal).
A R Dahl
Drug metabolism and disposition: the biological fate of chemicals, 10(5), 553-554 (1982-09-01)
A M Verweij et al.
Archiv fur Kriminologie, 190(1-2), 24-28 (1992-07-01)
Some impurities of illegally synthesized 3.4-(methylenedioxy)amphetamine (MDA) are presented. These compounds were detected in laboratory glassware which had been used for the synthesis of MDA via phenyl nitropropene route.
G G Kasymova et al.
Morfologiia (Saint Petersburg, Russia), 120(6), 42-47 (2002-05-23)
Structural changes of thymus in heliotrin hepatitis were characterized by distinct dynamics which on the whole suggested the progressing hypoplasia of its cortex. Immunostimulants parandin and thymalin suppressed the extent of thymocyte destruction and stimulated their mitotic activity. Although these...
J Sekizawa et al.
Mutation research, 101(2), 127-140 (1982-04-01)
The genotoxicity of safrole, 9 compounds that are structurally similar to safrole (anethole, cinnamaldehyde, cinnamyl alcohol, estragole, methyl eugenol, eugenol, isoeugenol, isosafrole, piperonal), 5 essential oils, cassia oil, cinnamon bark oil, clove oil, fennel oil) which contain the chemicals tested...
L I Shevchenko et al.
Eksperimental'naia i klinicheskaia farmakologiia, 66(4), 53-55 (2003-10-16)
Succivil, a drug based on the blood substitute succinasol and containing 1,4-naphthoquinone, was studied as a means of restoring the living activity of cells occurring under extremal conditions of alcohol, heliotrin, or combined intoxication. A thorough investigation of the role...
S B Stanfill et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 41(2), 303-317 (2002-12-14)
Indian-made bidi cigarettes sold in the United States are available in a variety of exotic (e.g. clove, mango) and candy-like (e.g. chocolate, raspberry) flavors. Because certain tobacco flavorings contain alkenylbenzenes and other toxic or carcinogenic chemicals, we measured the concentration...
Head louse repellents.
J Ibarra et al.
Journal of the Royal Society of Health, 114(2), 108-108 (1994-04-01)
A R Dahl et al.
Biochemical pharmacology, 34(5), 631-636 (1985-03-01)
Eighteen methylenedioxyphenyl (MDP) compounds, including some commonly inhaled by people, were tested for the ability to inhibit rabbit nasal microsomal cytochrome P-450-dependent hexamethylphosphoramide (HMPA) N-demethylase. For comparison, liver microsomes were also used. Nasal cytochrome P-450 from rabbits metabolized MDP compounds...
S Peock et al.
Journal of the Royal Society of Health, 113(6), 292-294 (1993-12-01)
Piperonal, once used to kill lice in Australian hospitals, was acclaimed as an effective pediculicide (Corlette, 1925) by the standards of the day. It is unusual in also exhibiting a repellent action against lice, a property only recently realised. A...
Ariel Ceferino Toloza et al.
Memorias do Instituto Oswaldo Cruz, 101(1), 55-56 (2006-05-16)
New alternative insecticides are necessary for the chemical control of head lice. In this study the fumigant knockdown time 50% (KT50) and repellency index (RI) of three aliphatic lactones was compared with two essential oils and DDVP, against permethrin-resistance Pediculus...
S Yamauchi et al.
Bioscience, biotechnology, and biochemistry, 64(11), 2320-2327 (2001-02-24)
The threo-selective aldol condensation of (3R, 4S)-3-hydroxy-5-trityloxy-4-pentanolide, which was prepared from L-arabinose, with piperonal was applied to the stereoselective synthesis of the olivil type of lignan, (2R, 3R, 4R)-4-benzyl-4-hydroxy-3-hydroxymethyl-2-(3,4-methylenedioxyphenyl)tetrahydrofuran.
Hisashi Matsuda et al.
Bioorganic & medicinal chemistry, 17(20), 7313-7323 (2009-09-25)
The 80% aqueous acetone extract from the fruit of Piper chaba (Piperaceae) was found to have hepatoprotective effects on D-galactosamine (D-GalN)/lipopolysaccharide-induced liver injury in mice. From the ethyl acetate-soluble fraction, three new amides, piperchabamides E, G, and H, 33 amides...
K Kónya et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 8(6), 454-459 (2002-02-05)
A series of naturally occurring 8.0.4'-neolignans (1a-d, 1g, 2g, 2h) and their analogues (le-f, lh, 1i, 2a-f, 2i) have been synthesized in racemic form starting from commercially available phenols, such as eugenol, isoeugenol and 4-allyl-2,6-dimethoxyphenol and from aromatic aldehydes, such...
Hisashi Matsuda et al.
Bioorganic & medicinal chemistry letters, 18(6), 2038-2042 (2008-02-22)
The methanolic extract from the fruit of Piper chaba (Piperaceae) was found to have a hepatoprotective effect on D-galactosamine (D-GalN)/lipopolysaccharide (LPS)-induced liver injury in mice. From the ethyl acetate-soluble fraction, a new amide constituent named piperchabamide E together with twenty...
S R Deshpande et al.
Indian journal of pharmaceutical sciences, 77(1), 24-33 (2015-03-15)
A series of novel 3, 4-methylenedioxybenzene scaffold incorporated 1,3,5-trisubstituted-2-pyrazoline derivatives was synthesised as potent antitubercular agents via chalcone intermediates by reaction with hydrazines. The structures of the compounds were confirmed by IR, 1HNMR, 13CNMR and mass spectral data. The novel...
H Hatt et al.
Cellular and molecular biology (Noisy-le-Grand, France), 45(3), 285-291 (1999-07-01)
The human olfactory system can recognize and discriminate a large number of different odorant molecules. The detection of chemically distinct odorants begins with the binding of an odorant ligand to a specific receptor protein on the olfactory neuron cell surface....
W H Redd et al.
Journal of magnetic resonance imaging : JMRI, 4(4), 623-626 (1994-07-01)
Fifty-seven outpatients received either heliotropin (a vanillalike scent) with humidified air (n = 20) or humidified air alone (n = 37) via a nasal cannula during magnetic resonance imaging in the diagnostic workup for cancer. Delivery of heliotropin and air...
Floyd Beckford et al.
Journal of inorganic biochemistry, 105(8), 1019-1029 (2011-06-15)
The synthesis and characterization of a number of organometallic ruthenium(II) complexes containing a series of bidentate thiosemicarbazone ligands derived from piperonal is reported. The structure of compounds have been confirmed by spectroscopic analysis (IR and NMR) as well as X-ray...
Kh Ia Karimov et al.
Likars'ka sprava, (3-4)(3-4), 123-127 (2002-07-31)
Prominent features of heliotrin-related chronic toxical disorders of the liver developing in hepatic cirrohosis include hyperfermentemia, hypoproteinemia, intensification of lipid peroxidation (LPO), as evidenced by decrease in the activity of the antioxidant defence. In chronic active liver disorders, hyperfermentemia and...
K C Nicolaou et al.
Journal of the American Chemical Society, 130(39), 13110-13119 (2008-09-06)
The molecular design, chemical synthesis, and biological evaluation of two distinct series of platensimycin analogues with varying degrees of complexity are described. The first series of compounds probes the biological importance of the benzoic acid subunit of the molecule, while...
Michael S Macias et al.
Forensic science international, 195(1-3), 132-138 (2010-01-02)
Currently, in the field of odor detection, there is generally a wider variation in limit of detections (LODs) for canines than instruments. The study presented in this paper introduces an improved protocol for the creation of controlled odor mimic permeation...
M Abdurakhmanov et al.
Eksperimental'naia i klinicheskaia farmakologiia, 62(6), 66-68 (2000-01-29)
Long-term entry of the hepatotropic poison heliotropin induces the development of chronic active hepatitis attended with disturbance of the immune balance and hematologic disorders in it. Immunomodulin alleviates the destructive changes in the organs of the immune system, stimulates proliferation...
Metabolism of piperonal and piperonyl alcohol in the rat with special reference to the scission of the methylenedioxy group.
J Klungsøyr et al.
Acta pharmaceutica Suecica, 21(1), 67-72 (1984-01-01)
S B Stanfill et al.
Journal of agricultural and food chemistry, 48(4), 1298-1306 (2000-04-25)
Little is known about the possible health effects associated with inhaling alkenylbenzenes through cigarette smoking, even though these flavor-related compounds have known toxic effects in animals. We developed a rapid and sensitive solid-phase extraction (SPE) method to quantify seven alkenylbenzenes...
Alberdan Silva Santos et al.
Applied biochemistry and biotechnology, 105 -108, 649-657 (2003-05-02)
The biotransformation of isosafrole by Cladosporium sphaerospermum yielded piperonal, which is a compound of great commercial importance in the flavor and fragrance industries. The experiments were performed in 500-mL conical flasks containing 100 mL of Czapek-modified medium in an orbital...
F Sh Inoiatov
Eksperimental'naia i klinicheskaia farmakologiia, 63(2), 67-70 (2000-06-02)
Experiments on rats with heliotrine-induced acute liver damage showed the main parameters of biochemical detoxication to be inhibited. Treatment of the test animals with perftoran increased the initially low level of microsomal hemoproteins, the activity of enzymes participating at the...
Huilin Liu et al.
Journal of agricultural and food chemistry, 63(9), 2545-2549 (2015-02-24)
A novel optosensing chip was constructed by anchoring the fluorescence sensing material layer based on molecularly imprinted polymer (MIP) coated CdSe/ZnS quantum dots (QDs) on a chip for highly selective and sensitive optosensing of sesamol in sesame oil. Many factors...