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Showing 1-30 of 209 results for "P6744" within Papers
Anna Carnini et al.
PloS one, 7(5), e37755-e37755 (2012-06-06)
Heat shock proteins (Hsps) are a set of molecular chaperones involved in cellular repair. They provide protective mechanisms that allow cells to survive potentially lethal insults, In response to a conditioning stress their expression is increased. Here we examined the
Pablo J Giraudi et al.
Experimental and molecular pathology, 98(1), 85-92 (2014-12-24)
Non-alcoholic fatty liver disease is characterized by an initial accumulation of triglycerides that can progress to non-alcoholic steatohepatitis, which can ultimately evolve to cirrhosis and hepatocellular carcinoma. Hepatic stellate cells play a key role in liver fibrogenesis by an increased
Sujatha Kandasamy et al.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 46(3), 659-666 (2015-09-29)
Ten bacterial strains that utilize cyanide (CN) as a nitrogen source were isolated from cassava factory wastewater after enrichment in a liquid media containing sodium cyanide (1 mM) and glucose (0.2% w/v). The strains could tolerate and grow in cyanide
K M D'Souza et al.
American journal of physiology. Heart and circulatory physiology, 309(8), H1346-H1353 (2015-09-16)
Transient angiotensin-converting enzyme (ACE) inhibition induces persistent changes that protect against future nitric oxide synthase (NOS) inhibitor-induced cardiac fibrosis and inflammation. Given the role of fibroblasts in mediating these effects, the present study investigates whether prior ACE inhibition produced persistent
Qinglan Wang et al.
Life sciences, 266, 118819-118819 (2020-12-18)
To investigate the effects and mechanism of miR-322/424 in liver fibrosis. miR-322/424 expression in liver cirrhosis patients, mouse and rat liver fibrosis was determined by qPCR. Mice liver fibrosis was established by CCl4, and intervened by miR-322/424 agomir or antagomir.
Giuliana Magri et al.
Nature immunology, 15(4), 354-364 (2014-02-25)
Innate lymphoid cells (ILCs) regulate stromal cells, epithelial cells and cells of the immune system, but their effect on B cells remains unclear. Here we identified RORĪ³t(+) ILCs near the marginal zone (MZ), a splenic compartment that contains innate-like B
Histological and histochemical methods: Theory and practice (5th ed.)
JA Kiernan
Histological and Histochemical Methods: Theory and Practice (2015)
Ernesto Cortes et al.
EMBO reports, 20(1) (2018-12-13)
The mechanical properties of the tumor microenvironment are emerging as attractive targets for the development of therapies. Tamoxifen, an agonist of the G protein-coupled estrogen receptor (GPER), is widely used to treat estrogen-positive breast cancer. Here, we show that tamoxifen
Jia Qi et al.
Nature communications, 5, 5390-5390 (2014-11-13)
Electrical stimulation of the dorsal raphe (DR) and ventral tegmental area (VTA) activates the fibres of the same reward pathway but the phenotype of this pathway and the direction of the reward-relevant fibres have not been determined. Here we report
Charles T Putman et al.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 40(7), 671-682 (2015-06-04)
This study tested the hypothesis that elevating the intracellular phosphorylation potential (IPP = [ATP]/[ADP]free) within rat fast-twitch tibialis anterior muscles by creatine (Cr) loading would prevent fast-to-slow fibre transitions induced by chronic low-frequency electrical stimulation (CLFS, 10 Hz, 12 h/day).
Niina Dulova et al.
Environmental technology, 32(3-4), 439-446 (2011-07-26)
The efficiency of goethite, magnetite and iron powder (Fe0) in catalysing the Fenton-based oxidation of picric acid (PA) in aqueous solution was studied. The effect of pH, hydrogen peroxide concentration, and catalyst type and dosage on treatment efficacy was investigated.
Shuangping Zhao et al.
Nephrology (Carlton, Vic.), 20(9), 646-653 (2015-05-07)
The aim of this study was to investigate the effect of neutrophil gelatinase-associated lipocalin (NGAL) on the rat cecal ligation and puncture (CLP)-induced sepsis and the possible mechanism. Thirty male Sprague-Dawley rats underwent CLP as sepsis models and were randomized
Kenneth W Jackson et al.
Neoplasia (New York, N.Y.), 17(1), 43-54 (2015-01-28)
Tumor microenvironments (TMEs) are composed of cancer cells, fibroblasts, extracellular matrix, microvessels, and endothelial cells. Two prolyl endopeptidases, fibroblast activation protein (FAP) and prolyl oligopeptidase (POP), are commonly overexpressed by epithelial-derived malignancies, with the specificity of FAP expression by cancer
Keun-Yeong Jeong et al.
Journal of radiation research, 56(1), 37-45 (2014-09-17)
Existing therapies such as irradiation or sorafenib have limited success in the treatment of hepatocellular carcinoma (HCC) due to tumor recurrence and metastasis. Therefore, combination with other therapeutics is often considered. Macrophage inflammatory protein-1 alpha (MIP-1Ī±) is a member of
Benjamin Le CalvƩ et al.
Oncotarget, 7(22), 32100-32112 (2016-04-07)
Solid tumors often display chemotherapy resistance. Pancreatic ductal adenocarcinoma (PDAC) is the archetype of resistant tumors as current chemotherapies are inefficient. The tumor stroma and extracellular matrix (ECM) are key contributors to PDAC aggressiveness and to limiting the efficacy of
Carla Luana Dinardo et al.
American journal of physiology. Heart and circulatory physiology, 306(4), H505-H516 (2013-12-18)
Vascular smooth muscle cells (VSMCs) are thought to assume a quiescent and homogeneous mechanical behavior after arterial tree development phase. However, VSMCs are known to be molecularly heterogeneous in other aspects and their mechanics may play a role in pathological
Omer Ziv et al.
PLoS computational biology, 11(10), e1004453-e1004453 (2015-10-17)
Neural stem cells (NSCs) are progenitor cells for brain development, where cellular spatial composition (cytoarchitecture) and dynamics are hypothesized to be linked to critical NSC capabilities. However, understanding cytoarchitectural dynamics of this process has been limited by the difficulty to
Abigail L Mackey et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(6), 2266-2281 (2016-03-05)
With this study we investigated the role of nonsteroidal anti-inflammatory drugs (NSAIDs) in human skeletal muscle regeneration. Young men ingested NSAID [1200 mg/d ibuprofen (IBU)] or placebo (PLA) daily for 2 wk before and 4 wk after an electrical stimulation-induced
Vanessa Reame et al.
Biology of reproduction, 91(6), 151-151 (2014-10-24)
This study compares the impact of obesogenic environment (OE) in six different periods of development on sperm parameters and the testicular structure of adult rats and their correlations with sex steroid and metabolic scenario. Wistar rats were exposed to OE
Munevver Acikkol et al.
Journal of AOAC International, 98(3), 760-766 (2015-06-19)
A highly specific and selective analytical method using LC/MS/MS for the quantitative determination of ethyl glucuronide (EtG) in urine was developed and fully validated. Since the determination of EtG in urine may be possible days after the elimination of alcohol
Secil Koseoglu et al.
Blood, 126(5), 651-660 (2015-05-23)
Platelet activation results in profound morphologic changes accompanied by release of granule contents. Recent evidence indicates that fusion of granules with the plasma membrane during activation provides auxiliary membrane to cover growing actin structures. Yet little is known about how
Martin Burdel et al.
Journal of separation science, 36(5), 932-938 (2013-02-06)
Three modes of liquid-liquid based microextraction techniques--namely auxiliary solvent-assisted dispersive liquid-liquid microextraction, auxiliary solvent-assisted dispersive liquid-liquid microextraction with low-solvent consumption, and ultrasound-assisted emulsification microextraction--were compared. Picric acid was used as the model analyte. The determination is based on the reaction
Andre Picot, P. Grenouillet
Safety in the Chemistry and Biochemistry Laboratory (1994)
Meadhbh Ć Brennan et al.
Biomedical materials (Bristol, England), 10(4), 045019-045019 (2015-08-05)
A major limitation of the 2D culture systems is that they fail to recapitulate the in vivo 3D cellular microenvironment whereby cell-cell and cell-extracellular matrix (ECM) interactions occur. In this paper, a biomaterial scaffold that mimics the structure of collagen
To Carlos Fung et al.
Forensic science international, 212(1-3), 143-149 (2011-07-09)
Cyanoacrylate fuming is one of the most common techniques employed for the detection of latent fingermarks on non-porous surfaces such as plastic and glass. The technique is generally applied by exposing items of interest to the vapours generated by heating
Lynn Yap et al.
Cell reports, 26(12), 3231-3245 (2019-03-21)
Regeneration of injured human heart muscle is limited and an unmet clinical need. There are no methods for the reproducible generation of clinical-quality stem cell-derived cardiovascular progenitors (CVPs). We identified laminin-221 (LN-221) as the most likely expressed cardiac laminin. We
Tom Flossmann et al.
Cell reports, 26(12), 3173-3182 (2019-03-21)
Synchronized activity is a universal characteristic of immature neural circuits that is essential for their developmental refinement and strongly depends on GABAergic neurotransmission. A major subpopulation of GABA-releasing interneurons (INs) expresses somatostatin (SOM) and proved critical for rhythm generation in
Charoen Kaitwatcharachai et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 94 Suppl 4, S135-S139 (2011-11-03)
Previous studies showed that high glucose in dialysate could interfere with creatinine measurement. This error might produce some mistakes in peritoneal dialysis (PD) treatment. The correction of creatinine is essentially needed. Creatinine powder diluted in 0.1 N HCl was used
Jeremy V Camp et al.
Journal of virology, 89(17), 8733-8748 (2015-06-13)
Infection of the lower respiratory tract by influenza A viruses results in increases in inflammation and immune cell infiltration in the lung. The dynamic relationships among the lung microenvironments, the lung, and systemic host responses during infection remain poorly understood.
K M Fernandes et al.
Medical and veterinary entomology, 29(3), 245-254 (2015-05-15)
The mosquito Stegomyia aegypti (=Aedes aegypti) (Diptera: Culicidae) is a vector for the dengue and yellow fever viruses. As blood digestion occurs in the midgut, this organ constitutes the route of entry of many pathogens. The effects of the insecticide
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