Showing 1-20 of 20 results for "P7081"
Yozo Okazaki et al.
Nature communications, 4, 1510-1510 (2013-02-28)
Phosphorus supply is a major factor responsible for reduced crop yields. As a result, plants utilize various adaptive mechanisms against phosphorus depletion, including lipid remodelling. Here we report the involvement of a novel plant lipid, glucuronosyldiacylglycerol, against phosphorus depletion. Lipidomic...
Horia I Petrache et al.
Journal of lipid research, 47(2), 302-309 (2005-11-04)
Critical to biological processes such as membrane fusion and secretion, ion-lipid interactions at the membrane-water interface still raise many unanswered questions. Using reconstituted phosphatidylcholine membranes, we confirm here that multilamellar vesicles swell in salt solutions, a direct indication that salt...
Charles Banliat et al.
Theriogenology, 135, 65-72 (2019-06-17)
Sperm capacitation, fertilization and embryo development take place in the oviduct during the periovulatory period of the estrous cycle. Phospholipids are crucial metabolites for sperm capacitation and early embryo development. The aim of this study was to monitor the abundance...
M Röpke et al.
Comparative biochemistry and physiology. Part A, Physiology, 118(2), 211-214 (1997-11-20)
Ion transport in both the frog skin (a high-resistance epithelium) and the rabbit nasal airway epithelium (a low-resistance epithelium) are dominated by electrogenic Na+ absorption via apical membrane amiloride-sensitive Na+ channels, and short-circuit current (ISC) is essentially a measure of...
Jef L N Wolfs et al.
Molecular membrane biology, 20(1), 83-91 (2003-05-15)
Membrane-perturbing agents that cause transformation of biconcave erythrocytes into echinocytes or stomatocytes were used to investigate the influence of erythrocyte shape on the rate of Ca(2+)-induced scrambling of phospholipids. Erythrocytes were treated with a variety of lipid-soluble compounds to induce...
Kenichi Ishibashi et al.
Biochimie, 177, 98-107 (2020-08-22)
The dietary intake of elaidate (elaidic acid), a trans-fatty acid, is associated with the development of various diseases. Since elaidate is a C18 unsaturated fatty acid with a steric structure similar to that of a C18 saturated fatty acid (stearate)...
Cosmin L Pocanschi et al.
Journal of molecular biology, 355(3), 548-561 (2005-11-29)
Membrane protein insertion and folding was studied for the major outer membrane protein of Fusobacterium nucleatum (FomA), which is a voltage-dependent general diffusion porin. The transmembrane domain of FomA forms a beta-barrel that is predicted to consist of 14 beta-strands....
M Röpke et al.
The American journal of physiology, 271(4 Pt 1), L646-L655 (1996-10-01)
We investigated the mechanism of interference of mucosal application of the short-chain phospholipid didecanoyl-L-alpha-phosphatidylcholine (DDPC; 0.1-0.5%) with ion transport pathways in isolated rabbit nasal airway epithelium (RNAE). Transports of Na+ and Cl- were evaluated from tracer ion fluxes, short-circuit current...
C Vermehren et al.
Drug metabolism and disposition: the biological fate of chemicals, 25(9), 1083-1088 (1997-10-06)
The absorption enhancer, didecanoylphosphatidylcholine (DDPC), improves the nasal absorption of human growth hormone in rabbits. We elucidated the uptake and the metabolism of 1,2-di[1-14C]decanoyl-L-3-phosphatidylcholine and 1,2-didecanoyl-L-3-phosphatidyl[N-methyl-3H]choline in rabbit nasal mucosa in vivo. One minute after nasal application of DDPC, 4.4-7.5%...
Cécile Loudet et al.
Biochimica et biophysica acta, 1724(3), 315-323 (2005-06-18)
Mixtures of dicaproyl- (DC), dimyristoyl- (DM) and 1-tetradecanoyl-2-biphenylbutanoyl-(TBB) phosphatidylcholine (PC) in water produce bicelle membranes that are oriented by magnetic fields. DMPC/DCPC systems orient such that their membrane plane is parallel to the magnetic field, whereas for TBBPC/DCPC, the plane...
C Agerholm et al.
Journal of pharmaceutical sciences, 83(12), 1706-1711 (1994-12-01)
The transepithelial transport of biosynthetic human growth hormone (hGH) formulated with the absorption enhancers didecanoyl-L-alpha-phosphatidylcholine (DDPC) and alpha-cyclodextrin (alpha-CD) was studied after intranasal administration to rabbits. Plasma concentrations of the hormone were determined until 240 min post administration by ELISA...
Vivek S Purohit et al.
The AAPS journal, 8(2), E362-E370 (2006-06-27)
Replacement therapy with exogenous recombinant factor VIII (rFVIII) to control bleeding episodes results in the development of inhibitory antibodies in 15% to 30% of hemophilia A patients. The inhibitory antibodies are mainly directed against specific and universal immunodominant epitopes located...
Qunfeng Zhang et al.
Tree physiology, 41(2), 317-330 (2020-10-27)
It is well known that green tea made from fully developed leaves located at the base of young shoots is of lower quality than that made from the still developing leaves located on the top of the shoot. It has...
M A Unmack et al.
Pflugers Archiv : European journal of physiology, 434(3), 234-241 (1997-07-01)
The effects of mucosal application of the short-chain phospholipid didecanoyl-L-alpha-phosphatidylcholine (DDPC; with two saturated 10-carbon acyl chains) on active Na+ transport and transepithelial conductance (G) in the frog skin (Rana temporaria) were investigated. Active Na+ transport was measured as the...
S Carstens et al.
Diabetes, 42(7), 1032-1040 (1993-07-01)
To investigate the short-term effects of didecanoyl-L-alpha-phosphatidylcholine on the nasal mucosa and the mechanism by which didecanoyl-L-alpha-phosphatidylcholine enhances the nasal absorption of insulin, an in vitro model was developed. The mucosa from the posterior part of the rabbit nasal septum...
J Y Legendre et al.
Biochemical and biophysical research communications, 217(1), 179-185 (1995-12-05)
Addition of short-chain phospholipids to the gramicidin S-DNA-dioleoyl phosphatidylethanolamine complex enhanced up to 6-fold beta-galactosidase expression in several cell-lines in vitro. Among the compounds tested, the most potent in enhancing transfection were the dicapryl- and the dicapryloyl phosphatidylcholine. In contrast...
T Laursen et al.
The Annals of pharmacotherapy, 28(7-8), 845-848 (1994-07-01)
Current growth hormone (GH) therapy with daily subcutaneous injections results in elevated serum concentrations of GH lasting for several hours, whereas physiologic GH secretion is characterized by a short-duration peak and low basal concentrations. A closer imitation of this pattern...
Studies on the complex formed between glucagon and dicaprylphosphatidylcholine.
J R Ernandes et al.
Biochimica et biophysica acta, 733(1), 75-86 (1983-08-24)
Effect of absorption enhancers on ciliated epithelium: a novel in vivo toxicity screening method using rotifers.
E Adriaens et al.
Pharmaceutical research, 14(4), 541-545 (1997-04-01)

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